Aminophenols
Medchemexpress LLC Ski V | 24418-86-8 | MFCD07772193 | 99.0% | 254.24 g/mol | C15H10O4 | 5 MG
SKI V is a small-molecule sphingosine kinase inhibitor reported to induce apoptosis and exhibit antitumor activity in vitro. The compound is supplied as a powder for laboratory research, with molecular formula C15H10O4 and molecular weight 254.24 g/mol. Solubility and activity data support formulation in DMSO and mixed aqueous vehicles for cell-based studies.
- Inhibits sphingosine kinase and PI3K signaling.
- Demonstrates in vitro activity (IC50 ≈ 2 μM for GST-hSK).
- Reported IC50 values for additional targets provide selectivity context.
- Supplied as a powder suitable for laboratory handling and storage.
- Soluble in DMSO (~50 mg/mL) and formulatable in aqueous vehicles with co-solvents.
- Molecular weight 254.24 g/mol; chemical formula C15H10O4.
- Intended for research use only.
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | 99.9% | 1 ML
Metixene hydrochloride hydrate is supplied as a 10 mM solution in DMSO for research use. It is the hydrochloride salt of metixene, an anticholinergic and antiparkinsonian agent, provided in a 1 mL vial.
- Ready-to-use 10 mM solution in DMSO.
- Compact 1 mL vial for small-scale assays.
- High purity suitable for research applications.
- Molecular formula C20H26ClNOS, molecular weight 363.94 g/mol.
- Suitable for in vitro pharmacology and receptor studies.
Medchemexpress LLC PZ703b hydrochloride | 2471970-56-4 | 99.2% | 1636.90 | 1 MG
PZ703b hydrochloride | 2471970-56-4 | 99.2% | 1636.90 | 1 MG
Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.2% | 516.42 | 25 MG
CX-6258 hydrochloride hydrate is a potent and selective pan-Pim kinases inhibitor. It effectively inhibits Pim-1, Pim-2, and Pim-3, making it suitable for research into cancer and metabolic diseases.
- Potent and kinase selective pan-Pim kinases inhibitor
- Inhibits Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM), and Pim-3 (IC50: 16 nM)
- Causes dose-dependent inhibition of phosphorylation of pro-survival proteins, Bad and 4E-BP1
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells
- Exhibits robust in vivo efficacy in Pim kinases driven tumor models
- Achieves 45% tumor growth inhibition at 50 mg/kg and 75% at 100 mg/kg in vivo
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 50MG
Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 50MG
Medchemexpress LLC LY266097 hydrochloride | 172895-39-5 | 99.6% | 407.33 g/mol | C21H24Cl2N2O2 | 1 ML
A selective 5-HT2B receptor antagonist supplied as the hydrochloride salt for laboratory research applications. It is used in vitro and in vivo to study 5-HT2B-mediated signaling and neurotransmitter modulation. For research use only.
- High purity, 99.6%.
- Molecular weight 407.33 g/mol.
- Molecular formula C21H24Cl2N2O2.
- Available as 10 mM 1 mL solution in DMSO or as solid vials (5-100 mg).
- Recommended storage: sealed at -80°C up to 6 months or at -20°C up to 1 month.
Medchemexpress LLC Melatonin-d7 | 615251-68-8 | 98.0% | C13H9D7N2O2 | 1 MG
Melatonin-d7 is a deuterium-labeled version of melatonin, a hormone produced by the pineal gland. It activates melatonin receptors and is involved in sleep, exhibiting significant antioxidative and anti-inflammatory properties. Melatonin-d7 also acts as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells through endoplasmic reticulum stress.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Rs 17053 hydrochloride | 169505-93-5 | 99.9% | 449.41 g/mol | C24H30Cl2N2O2 | 10 MG
RS 17053 hydrochloride is a potent, selective α1A adrenoceptor antagonist for pharmacological research. It exhibits high affinity in native membranes (pKi 9.1) and functional potency (pA2 9.8), with marked selectivity versus α1B and α1D subtypes. The material is supplied as a high-purity solid and is provided in multiple sizes and a DMSO solution format for laboratory use.
- Potent, selective α1A adrenoceptor antagonist with reported pKi 9.1 and pA2 9.8.
- Substantial selectivity versus α1B and α1D receptor subtypes.
- High purity suitable for sensitive pharmacology assays.
- Available as a solid and as a ready-to-use DMSO solution for convenience.
- Intended for research use in receptor binding and functional studies.
eMolecules 6291-01-6 | Cyclobutanamine hydrochloride | ChemScene | MFCD00034953 | 107.580 | C4H10ClN | 97.000 | Cl.NC1CCC1 | 5g | 536772990
Cyclobutanamine hydrochloride | ChemScene | 6291-01-6 | MFCD00034953 | 107.580 | C4H10ClN | 97.000 | Cl.NC1CCC1 | 5g | 536772990
Medchemexpress LLC L-NAME (hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 25 G
L-NAME hydrochloride inhibits NOS with an IC50 of 70 μM. It is a precursor to the NOS inhibitor L-NOARG, which has an IC50 value of 1.4 μM. This product is intended for research use only and can be used to induce hypertension and preeclampsia models.
- Inhibits NOS with an IC50 of 70 μM.
- Functions as a precursor to the NOS inhibitor L-NOARG.
- Suitable for inducing hypertension models.
- Suitable for inducing preeclampsia models.
- Exhibits a purity of 99.89%.
