Aminophenols
Medchemexpress LLC CX-6258 (hydrochloride) | 1353859-00-3 | 99.0% | 498.40 | 1 ML
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. It is for research use only and not sold to patients.
- Potent and kinase selective pan-Pim kinases inhibitor
- Inhibits Pim-1 with an IC50 of 5 nM, Pim-2 with an IC50 of 25 nM, and Pim-3 with an IC50 of 16 nM
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites (S112, S65, T37/46)
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells and reduces NKX3.1 half-life
- Exhibits robust in vivo efficacy in two Pim kinases driven tumor models, with 50 mg/kg producing 45% tumor growth inhibition (TGI) and 100 mg/kg producing 75% TGI
eMolecules 103-90-2 | Acetaminophen | Combi-Blocks | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 5g | 335345644
Acetaminophen | Combi-Blocks | 103-90-2 | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 5g | 335345644
eMolecules 1338545-07-5 | Medchem Express | OTS964 (hydrochloride) | 5mg | 446261301 | HY-12467 | MFCD28386220 | 428.98 | C23H25ClN2O2S
1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate | Ambeed | 161491-24-3 | MFCD08752608 | 257.286 | C12H19NO5 | 97.000 | COC(=O)C1CN(CCC1=O)C(=O)OC(C)(C)C | 10g | 525075769
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eMolecules 51-78-5 | 4-Aminophenol hydrochloride | Combi-Blocks | MFCD00012996 | 145.590 | C6H8ClNO | 97.000 | Cl.Nc1ccc(O)cc1 | 25g | 537622500
4-Aminophenol hydrochloride | Combi-Blocks | 51-78-5 | MFCD00012996 | 145.590 | C6H8ClNO | 97.000 | Cl.Nc1ccc(O)cc1 | 25g | 537622500
eMolecules 263717-53-9 | Medchem Express | Propyl pyrazole triol | 5mg | 475641433 | HY-100689 | MFCD03453628 | 386.451 | C24H22N2O3
Ambeed | 1245-Tetrabromobenzene | 1g | 642080428 | A248034 | 636-28-2 | MFCD00000063 | 393.698 | C6H2Br4
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Medchemexpress LLC RS 67333 (hydrochloride) | 168986-60-5 | MFCD00938576 | 99.7% | 389.36 | C19H30Cl2N2O2 | 25 MG
RS 67333 hydrochloride is a research-grade, selective 5-HT4 receptor partial agonist used in preclinical and in vitro neuroscience studies to investigate serotonergic signaling and neuroprotective mechanisms.
- Potent, selective 5-HT4 receptor partial agonist for neuroscience research.
- High purity, 99.7% (as listed by manufacturer).
- Molecular weight 389.36 g/mol; formula C19H30Cl2N2O2.
- Solid, light yellow to yellow appearance supplied as a dry powder.
- Storage: 4°C, sealed and away from moisture; in solvent store at -80°C for long-term.
- Available as a 25 MG vial for laboratory use.
- CAS number 168986-60-5.
Medchemexpress LLC Pirmenol hydrochloride | 61477-94-9 | MFCD01691662 | 98.8% | 374.95 g·mol⁻¹ | C22H31ClN2O | 100 MG
Pirmenol hydrochloride is an orally active antiarrhythmic research compound used in pharmacology and electrophysiology studies. It inhibits IK.ACh currents by blocking muscarinic acetylcholine receptors and is provided as a high-purity solid for laboratory research use.
- Orally active compound suitable for cellular and in vivo studies.
- Reported to inhibit IK.ACh with IC50 ≈ 0.1 μM.
- High purity solid for reproducible experimental results.
- Available in small-quantity packages appropriate for research workflows.
- Intended for laboratory research; not for human or diagnostic use.
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 100 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This compound is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Exhibits high potency and selectivity for PAD2.
- Effectively inhibits H3 citrullination.
- Has shown low cytotoxicity in HEK293T/PAD2 cells.
- Can suppress NLRP3 signaling, decreasing airway remodeling in PAD2-/- transgenic mice.