Aminophenols
Medchemexpress LLC AZD9056 hydrochloride | 345303-91-5 | 98.2% | 455.46 | 5 MG
AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases. It is for research use only.
- Selective orally active inhibitor of P2X7
- Plays a significant role in inflammation and pain-causing diseases
- Has a clear inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells
- Exerts pain-relieving and anti-inflammatory effects
- Reverses the upregulated expression of interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), matrix metalloproteinase-13 (MMP-13), substance P (SP) and prostaglandin E2 (PGE2) which is induced by MIA in cartilage tissues
Cayman Chemical Acetaminophen Inhibitors
An analgesic and antipyretic compound; an inhibitor of COX-2 that is selective over COX-1 (IC50s = 113.7 and 25.8 µM, respectively, in human blood ex vivo); induces ferroptotic cell death in primary mouse hepatocytes; has a metabolite that depletes glutathione reserves in the liver
Medchemexpress LLC NNC 92-1687 | 1MG
NNC 92-1687 is a non-peptide competitive human glucagon receptor antagonist (IC50 20 M Ki 9 1 M) NNC 92-1687 can be used in the research of type 2 diabetes[1]
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 100 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This compound is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Exhibits high potency and selectivity for PAD2.
- Effectively inhibits H3 citrullination.
- Has shown low cytotoxicity in HEK293T/PAD2 cells.
- Can suppress NLRP3 signaling, decreasing airway remodeling in PAD2-/- transgenic mice.
Selleck Chemical LLC OTS514 hydrochloride-2mg
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2.6 nM. OTS514 induces cell cycle arrest and apoptosis.
eMolecules AstaTech / (R)-1-(35-DICHLOROPHENYL)ETHYLAMINE / 0.25g / 200619803 / SC1347 / 95.000 / 617710-53-9 / MFCD07772552 / 190.070 / C8H9Cl2N
AstaTech / (R)-1-(35-DICHLOROPHENYL)ETHYLAMINE / 0.25g / 200619803 / SC1347 / 95.000 / 617710-53-9 / MFCD07772552 / 190.070 / C8H9Cl2N
![Medchemexpress LLC 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride | 131780-48-8 | MFCD00911718 | 99.0% | 351.83 g/mol | C17H22ClN3O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242163.png-250.jpg)
Medchemexpress LLC 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride | 131780-48-8 | MFCD00911718 | 99.0% | 351.83 g/mol | C17H22ClN3O3 | 5 MG
DAU 5884 hydrochloride is a potent, selective muscarinic M3 receptor antagonist provided as the hydrochloride salt for research use. It is used in vitro to study muscarinic receptor-mediated signaling, including methacholine-dependent cell proliferation and smooth muscle contractility.
- Potent M3 receptor antagonist suitable for in vitro pharmacology.
- Inhibits methacholine-dependent cell proliferation and muscle contractility.
- High reported purity for reliable experimental results.
- Available in small milligram quantities for screening and characterization.
- Soluble in water and DMSO for diverse assay formats.
- Provided as a hydrochloride salt for improved stability and handling.
Medchemexpress LLC Imiloxan hydrochloride | 81167-22-8 | 98.5% | 280.75 g/mol | C14H17ClN2O2 | 50 MG
Imiloxan hydrochloride is a research chemical that acts as a selective α2B-adrenoceptor antagonist, supplied as a solid and characterized for laboratory pharmacology studies. It is used to probe adrenergic receptor subtype function in vitro and in vivo, and is accompanied by analytical and safety documentation for research use only.
- Selective α2B-adrenoceptor antagonist for receptor subtype studies.
- High purity suitable for in vitro and in vivo experiments.
- Available in small milligram pack sizes for flexible dosing and formulation.
- Supplied with a product data sheet and safety data sheet for laboratory handling.
- Solid form enables precise weighing and preparation of solutions.
Medchemexpress LLC Mt-7716 hydrochloride | 1215859-93-0 | MFCD07778657 | 99.1% | 477.00 g·mol⁻¹ | C27H29ClN4O2 | 100 MG
MT-7716 hydrochloride is a selective non-peptide nociceptin receptor (NOP) agonist supplied as the hydrochloride salt for research use. It is investigated for reducing alcohol-seeking behavior and relapse, and is provided as a solid reagent for in vitro and in vivo pharmacology studies.
- Selective non-peptide nociceptin (NOP) receptor agonist.
- Investigated for reduction of alcohol seeking and relapse prevention.
- Provided as the hydrochloride salt in solid form for research applications.
- High purity (≈99.1%) suitable for analytical and pharmacology studies.
- Molecular formula C27H29ClN4O2, molecular weight 477.00 g·mol⁻¹.
- Storage: 4°C sealed, away from moisture; in solvent, -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC PD153035 hydrochloride | 183322-45-4 | 99.5% | 50 MG
PD153035 hydrochloride is the hydrochloride salt of a potent epidermal growth factor receptor (EGFR) inhibitor used in biochemical and cellular research. It is supplied as a high-purity, well-characterized small-molecule reagent with defined solubility and storage recommendations.
- Potent EGFR inhibitor with reported Ki = 6 pM and IC50 = 25 pM.
- High purity: 99.48%.
- Molecular formula C16H15BrClN3O2; molecular weight 396.67 g/mol.
- Soluble in DMSO (4 mg/mL); insoluble in water (< 0.1 mg/mL).
- Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
- Supplied as a 50 mg package for research use.