Aminophenols
Medchemexpress LLC HY-15373 100mg , Fenretinide 4-HPR;(4-Hydroxyphenyl)retinamide CAS:65646-68-6 Purity:98%
Medchemexpress, HY-15373 100mg Fenretinide 4-HPR;(4-Hydroxyphenyl)retinamide CAS:65646-68-6 Formula:C26H33NO2 Purity:98% Fenretinide is a synthetic retinoid deriverative, binding to the retinoic acid receptors ( RAR ) at concentrations necessary to induce cell death. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ethylenediaminetetraacetic acid sodium hydrate | 85715-60-2 | MFCD00149675 | 97.0% | 376.20 g/mol | C10H15N2Na3O9 | 25 G
EDTA sodium hydrate (ethylenediaminetetraacetic acid trisodium salt hydrate) is a sodium salt hydrate of EDTA used as a metal chelating agent and laboratory reagent. It binds divalent and trivalent metal ions to stabilize solutions and remove trace metals during buffer preparation, sample cleanup, and analytical assays. Supplied as a crystalline powder for research use.
- High purity (97.0%).
- Effective chelator of Ca2+ and Mg2+.
- Stable crystalline powder, easy to weigh and dissolve.
- Suitable for buffer preparation and analytical assays.
- Available in multiple pack sizes, including 25 g.
- Identified by CAS number 85715-60-2 for traceability.
TARGETMOL CHEMICALS INC ECOPLADIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ecopladib (PLA 725) is a sub-micromolar inhibitor of cytosolic phospholipase A2(alpha) (cPLA2(alpha)) with IC50s of 0.15 uM and 0.11 uM in the GLU micelle and rat whole blood assays respectively. purity: 99%
TARGETMOL CHEMICALS INC JHU395 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA) 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo resulting in significant antitumor activity in MPNST. Additionally JHU395 exhibits plasma stability. purity: 99%
Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 99.2% | C16H18Cl3N5O2 | 1 ML
AT7519 Hydrochloride is a potent inhibitor of cyclin-dependent kinases (CDKs), with low nanomolar IC50s for CDK1, CDK2, CDK4-CDK6, and CDK9. It induces cytotoxicity and apoptosis in multiple myeloma (MM) cells, linked to GSK-3β activation and inhibition of RNA polymerase II. The compound inhibits tumor growth in MM xenograft mouse models and has been involved in clinical trials for various cancers.
- Potent inhibitor of CDKs (CDK1, CDK2, CDK4-CDK6, CDK9)
- Induces cytotoxicity and apoptosis in MM cells
- Overcomes cytokine and BMSC protective effects
- Inhibits RNA polymerase II CTD phosphorylation and RNA synthesis
- Inhibits cell cycle progression and reduces antiapoptotic protein levels
- Inhibits tumor growth in MM xenograft mouse models
eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 40mg | 564356423
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 40mg | 564356423
Medchemexpress LLC NS8593 (hydrochloride) | 875755-24-1 | 99.8% | 299.80 | 25 MG
NS8593 hydrochloride is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels). It reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. It also inhibits SK1-3 subtypes in a Ca2+-dependent manner (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), but it does not affect intermediate and large conductance Ca2+-activated K+ channels (hIK and hBK channels).
- Potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor.
- Reversibly inhibits SK3-mediated currents.
- Active on apamin-insensitive SK3 channels.
- Affects firing rate and pattern of dopaminergic neurons in vivo.
Apexbio Technology LLC MOG (35-55) 149635-73-4 1mg
MOG (35-55) (CAS 149635-73-4) is a truncated peptide derived from human myelin oligodendrocyte glycoprotein (MOG) MOG an immunoglobulin superfamily glycoprotein specifically expressed in the central nervous system serves as a target antigen in experimental autoimmune encephalomyelitis (EAE) an animal model resembling multiple sclerosis (MS) The MOG (35-55) peptide induces strong inflammatory responses via activation of autoreactive T cells and promotion of autoantibody production leading to extensive demyelination Due to its prominent encephalitogenic properties it is widely utilized in preclinical research for studying MS pathogenesis and therapeutic interventions
eMolecules 127818-58-0 | 3-METHYL-5-NITROPHENOL | MFCD09038591 | 1g
Ambeed | 13-Benzenedimethanamine | 25g | 600851593 | A566345 | 1477-55-0 | MFCD00008119 | 136.198 | C8H12N2
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Medchemexpress LLC DMT-dI Phosphoramidite | 141684-35-7 | >98.1% | 754.81 | 1 ML
DMT-dI Phosphoramidite is a modified phosphoramidite monomer specifically utilized for oligonucleotide synthesis. It is presented as a solid, appearing in a white to off-white color. The product should be stored at 4°C in a sealed container, away from moisture and light. If stored in solvent, it maintains stability at -80°C for 6 months or at -20°C for 1 month under sealed conditions, also away from moisture and light.
- Appearance: Solid
- Color: White to off-white
- Storage:
- 4°C, sealed storage, away from moisture and light.
- In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture and light).
- Solubility: Soluble in DMSO at 125 mg/mL (165.60 mM), requiring ultrasonication.
Medchemexpress LLC V-0219 hydrochloride | 2922283-73-4 | 99.4% | C20H26ClF3N4O2 | 1 ML
V-0219 hydrochloride is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). This compound is suitable for research related to obesity-associated diabetes.
- Orally active GLP-1R positive allosteric modulator
- Useful for obesity-associated diabetes research
- Purity of 99.39%
- Molecular weight of 446.89
- Chemical formula: C20H26ClF3N4O2
- CAS number: 2922283-73-4
- Appearance: White to off-white solid
- Target: GLP-1R
Ambeed 2 1HImidazol4yl ethan1amine di
2-(1H-Imidazol-4-yl)ethan-1-amine dihydrochloride, 56-92-8, 98%
Medchemexpress LLC 4-tert-Octylphenol | 140-66-9 | 99.7% | 1000 G
4-tert-Octylphenol is an endocrine-disrupting chemical and an estrogenic agent, also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. It induces apoptosis in neuronal progenitor cells in offspring mouse brain, reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), which leads to a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice.
- Endocrine-disrupting chemical
- Estrogenic agent
- Biodegradation product of non-ionic surfactants alkylphenol polyethoxylates
- Induces apoptosis in neuronal progenitor cells in offspring mouse brain
- Reduces neuronal progenitor proliferation by affecting BrdU, Ki67, and phospho-histone H3
- Disrupts brain development and behavior in mice
- Promising for research of immune response, neuro-related diseases and ethology