RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. It significantly suppresses the growth of multiple cancer types in animals, including lung cancer, melanoma, glioblastoma, ovarian, renal cell, triple-negative breast, and colon cancer, with some instances showing partial or complete tumor regression.
- Small-molecule LXR agonist.
- Modulates innate immunity via transcriptional activation of the ApoE gene.
- Significantly suppresses the growth of multiple cancer types in animals.
- Treatment causes partial or complete tumor regression in some instances.
- Available in solid form and in solution.