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Filtered Search Results
Medchemexpress LLC Chlorprothixene hydrochloride | 6469-93-8 | 99.91% | 1 ML
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Chlorprothixene hydrochloride is an antagonist of dopamine and histamine receptors, exhibiting antipsychotic activity. It demonstrates specific Ki values for hD1, hD2, hD3, hD5, and hH1 receptors, and binds to 5-HT receptors with distinct pKis.
- Antagonist of dopamine and histamine receptors
- Exhibits antipsychotic activity
- Binds to 5-HT receptors
- Purity of 99.91%
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Medchemexpress LLC Benserazide (hydrochloride) | 14919-77-8 | MFCD00078571 | >98.0% | 5 G
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Benserazide hydrochloride, also known as Serazide, is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. It also acts as a PKM2 inhibitor by directly binding to and blocking PKM2 enzyme activity, which leads to the inhibition of aerobic glycolysis and concurrent up-regulation of OXPHOS. This compound is valuable in the study of Parkinson's disease and melanoma.
- Inhibits L-amino acid decarboxylase and L-DOPA decarboxylase.
- Acts as a PKM2 inhibitor by directly binding to and blocking its enzyme activity.
- Leads to inhibition of aerobic glycolysis and concurrent up-regulation of OXPHOS.
- Valuable in the study of Parkinson's disease.
- Applicable in melanoma studies.
- Target: Pyruvate kinase.
- Pathway: Metabolic enzyme/protease.
- Soluble in DMSO (100 mg/mL) and water (≥ 50 mg/mL).
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Medchemexpress LLC Venlafaxine hydrochloride | 99300-78-4 | 99.8% | 5 MG
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Venlafaxine hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. This compound acts as an antidepressant, effectively blocking the reuptake of both serotonin and norepinephrine in the brain, which contributes to its therapeutic effects. It is a well-characterized chemical with known molecular properties.
- Potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor
- Functions as an antidepressant
- Available in various quantities for research applications
- Recommended storage conditions for solid form: 4°C, sealed, away from moisture
- Recommended storage conditions for in-solvent form: -80°C for 2 years or -20°C for 1 year, sealed, away from moisture
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Medchemexpress LLC Venlafaxine (hydrochloride) | 99300-78-4 | 99.76% | 1 ML
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Venlafaxine hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor and an antidepressant.
- Potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor
- Antidepressant properties
- 99.76% purity
- Recommended storage at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 2 years or -20°C for 1 year
- Orally active
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Medchemexpress LLC Rimantadine (hydrochloride) | 1501-84-4 | 98.0% | 100 G
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Rimantadine hydrochloride is an orally active inhibitor for M2 protein, blocking hydrogen ion channel activity, preventing virus entry and replication, and exhibiting broad-spectrum antiviral activity. It is intended for research use only.
- Inhibits RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells.
- Increases LC3 expression and promotes autophagy in HAV-infected Huh7 cells.
- Exhibits anti-infectious activity in H3N2-infected mouse models, lowering lung virus titer.
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Medchemexpress LLC Rimantadine hydrochloride | 1501-84-4 | 98.0% | 1 G
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Rimantadine hydrochloride (Flumadine hydrochloride) is an orally active inhibitor for M2 protein that blocks hydrogen ion channel activity, preventing virus entry and replication. It exhibits broad-spectrum antiviral activity. It is for research use only and not sold to patients.
- Inhibits RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells with IC50 values of 6.7 and 1.6 μg/mL
- Increases expression of the autophagy marker LC3 and promotes autophagy in HAV-infected Huh7 cells
- Exhibits anti-infectious activity when combined with Oseltamivir in H3N2-infected mouse models
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Medchemexpress LLC Naratriptan hydrochloride | 143388-64-1 | 100 MG
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Naratriptan hydrochloride is an analytical standard intended for research and analytical applications. It is a selective 5-HT1B/1D receptor agonist that is peripherally active and exhibits good oral bioavailability. It induces cranial artery vasoconstriction by activating 5-HT1B/1D receptors, inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation, and reduces sterile inflammation.
- Analytical standard for research and analytical applications
- Selective 5-HT1B/1D receptor agonist
- Peripherally active with good oral bioavailability
- Induces cranial artery vasoconstriction
- Inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation
- Reduces sterile inflammation
- Used in research of acute migraine
- Commonly used in qualitative, quantitative, and methodological research experiments
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Medchemexpress LLC Naratriptan hydrochloride | 143388-64-1 | 99.7% | 5 MG
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Naratriptan hydrochloride (GR-85548A) is a selective 5-HT1B/1D receptor agonist. It is peripherally active and exhibits good oral bioavailability, causing cranial artery vasoconstriction by activating 5-HT1B/1D receptors. It also suppresses trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. It is primarily used in acute migraine research, targeting cranial vascular and neuroinflammatory mechanisms.
- Selective 5-HT1B/1D receptor agonist
- Peripherally active with good oral bioavailability
- Causes cranial artery vasoconstriction
- Suppresses trigeminal nerve-mediated dural neurogenic plasma extravasation
- Reduces sterile inflammation
- Targets human recombinant 5-HT1B and 5-HT1D receptors
- Inhibits plasma protein extravasation in rat dural neurogenic inflammation model
- High oral bioavailability in rats and dogs
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Medchemexpress LLC Venlafaxine (hydrochloride) | 99300-78-4 | MFCD03658865 | 99.99% | 5 MG
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Venlafaxine hydrochloride (Standard) is an analytical standard of Venlafaxine hydrochloride, intended for research and analytical applications. It is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor with antidepressant properties.
- Analytical standard for research and analytical applications
- Orally active
- Potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor
- Antidepressant properties
- Suitable for qualitative research experiments
- Suitable for quantitative research experiments
- Suitable for methodological research experiments
- Used in HPLC, GC, and MS applications
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Medchemexpress LLC Todralazine (hydrochloride) | 3778-76-5 | 99.9% | 1 ML
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Todralazine hydrochloride, also known as Ecarazine hydrochloride, is an anti-hypertensive agent. It functions as a β2AR blocker and exhibits antioxidant and free radical scavenging properties. This product is intended for research use only.
- Functions as a β2AR blocker
- Exhibits antioxidant activity
- Has free radical scavenging activity
- Recommended storage for solid form: -20°C, sealed, away from moisture
- Recommended storage for in-solvent form: -80°C for 6 months, or -20°C for 1 month, sealed, away from moisture
- Soluble in DMSO and water for in vitro use
- Suitable for various in vivo protocols
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Medchemexpress LLC Propafenone hydrochloride | 34183-22-7 | 98.5% | 1 ML
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Propafenone hydrochloride is an anti-arrhythmic medication primarily used to treat rapid heartbeats, including atrial and ventricular arrhythmias. It functions by slowing the influx of sodium ions into cardiac muscle cells, thereby reducing their excitability. This compound is notably more selective for cells exhibiting a high heart rate and also possesses beta-adrenergic blocking activity.
- Treats rapid heartbeats like atrial and ventricular arrhythmias.
- Slows sodium ion influx into cardiac muscle cells.
- Decreases cellular excitability.
- Selective for cells with high heart rates.
- Exhibits beta-adrenergic blocking activity.
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Medchemexpress LLC Cefmenoxime hydrochloride | 75738-58-8 | 99.3% | 5 G
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Cefmenoxime hydrochloride is a new semisynthetic cephalosporin antibiotic. It demonstrates antibacterial activity against a broad range of gram-positive and gram-negative bacteria.
- Acts as a β-lactam antibiotic.
- Exhibits broad-spectrum activity against various bacteria.
- Inhibits at least 90% of tested Enterobacteriaceae strains (MIC90 0.06 to 8 μg/mL) in vitro.
- Effective against Streptococcus pneumoniae (MIC90 0.015 μg/mL), Streptococcus pyogenes (MIC90 ≤0.008 μg/mL), and S. aureus (MIC90 2 μg/mL) in vitro.
- Shows activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis (MIC90 ≤0.008 to 0.25 μg/mL) in vitro.
- Improves survival rate in mice infected with lung bacteria (40 mg/kg, daily for 7 days, 60% mortality reduction) in vivo.
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Medchemexpress LLC Bupivacaine hydrochloride | 18010-40-7 | 99.85% | 1 ML
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Bupivacaine hydrochloride is an NMDA receptor inhibitor. It blocks sodium, L-calcium, and potassium channels, and potently blocks SCN5A channels with an IC50 of 69.5 μM. This product is used for research related to chronic pain.
- NMDA receptor inhibitor
- Blocks sodium, L-calcium, and potassium channels
- Potently blocks SCN5A channels with an IC50 of 69.5 μM
- Used for chronic pain research
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Medchemexpress LLC Perospirone hydrochloride | 129273-38-7 | 99.9% | 10 MM * 1 ML
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Perospirone hydrochloride (SM-9018) is an orally active antagonist of the 5-HT2A receptor (Ki of 0.6 nM) and dopamine D2 receptor (Ki of 1.4 nM). It also acts as a partial agonist of the 5-HT1A receptor (Ki of 2.9 nM). This compound is classified as an atypical antipsychotic agent and has potential for research related to schizophrenic disease. It is for research use only and not sold to patients.
- Orally active antagonist of the 5-HT2A receptor (Ki of 0.6 nM)
- Antagonist of the dopamine D2 receptor (Ki of 1.4 nM)
- Partial agonist of the 5-HT1A receptor (Ki of 2.9 nM)
- Classified as an atypical antipsychotic agent
- Potential for research into schizophrenic disease
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Medchemexpress LLC Hydralazine (hydrochloride) | 304-20-1 | 99.9% | 500 MG
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Hydralazine hydrochloride is an antihypertensive agent. It can inhibit mitochondrial fission and human peritoneal mesothelial cell proliferation. It also demonstrates immunomodulation and anti-migratory effects, and activates the intrinsic pathway of apoptosis, causing DNA damage.
- Antihypertensive agent
- Inhibits mitochondrial fission
- Inhibits human peritoneal mesothelial cell proliferation
- Demonstrates immunomodulation and anti-migratory effects
- Activates the intrinsic pathway of apoptosis
- Causes DNA damage
- Induces caspase-dependent apoptosis
- Prevents H2O2-induced mitochondrial fragmentation and depolarization
- Plays a pro-regeneration role in spinal cord injury mice
- Reduces leukocyte migration
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