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Filtered Search Results
Medchemexpress LLC GM-CSF 100ug | 100ug
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GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2 GM-CSF R alpha binds to the cytokine with high specificity and low affinity[1] GM-CSF R alpha binds to GM-CSF and induces cell differentiation[2] GM-CSF R alpha monoclonal antibody decreases GM-CSFR expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA)[3] GM-CSF R alpha Protein Human (Biotinylated HEK293 His-Avi) is a biotinylated recombinant protein with a C-Terminal His label and a C-Terminal Avi label It consists of 298 amino acids (E23-G320) and is produced in HEK293 cells
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Medchemexpress LLC (-)-Isopulegol | 89-79-2 | 99.8% | 100 G
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Isopulegol is a chiral monoterpene alcohol used as a research reagent and intermediate in antiviral and synthetic chemistry studies. It is supplied in laboratory pack sizes and used as a building block for further chemical transformations.
- Chiral monoterpene alcohol suitable for research applications.
- Cas number 89-79-2 for unambiguous identification.
- Purity typically around 99.8% (reported values vary by batch).
- Molecular weight 154.25 g/mol.
- Soluble in DMSO for experimental use.
- Available in 100 G pack sizes for synthesis and scale-up.
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Medchemexpress LLC Bromo-PEG1-C2-azide | 1144106-65-9 | 99.45% | C4H8BrN3O | 50 MG
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Bromo-PEG1-C2-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It also serves as a click chemistry reagent, featuring an azide group.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Medchemexpress LLC Sesamol | 533-31-3 | 138.12 | 100 G
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Sesamol, a constituent of sesame oil, exhibits potent free radical scavenging, anti-oxidant, and anticancer activities, acting as a classical inhibitor of lipid peroxidation. It effectively induces apoptosis in human liver hepatocellular carcinoma (HepG2) cells by impairing mitochondrial function and suppressing autophagy. Sesamol also suppresses cell proliferation and triggers both intrinsic and extrinsic apoptosis pathways.
- Free radical scavenger
- Anti-oxidant and anticancer properties
- Inhibits lipid peroxidation
- Induces apoptosis in HepG2 cells
- Suppresses cell proliferation
- Triggers intrinsic and extrinsic apoptosis pathways
- Impairs mitochondrial function
- Inhibits mitophagy and autophagy
- Reduces anti-apoptotic protein Bcl-2
- Activates extrinsic apoptosis (Fas/FasL, tBid, caspase-8)
- Inhibits M-HeLa cell growth
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Medchemexpress LLC Cathepsin C/DPPI protein, mouse (inactive, His-Myc) | >95.0% | 250UG
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Recombinant inactive mouse Cathepsin C/DPPI protein fragment expressed in E. coli and supplied lyophilized with N-terminal 10xHis and C-terminal Myc tags. The product corresponds to residues D25-W134, is provided at high purity, and is intended for biochemical, structural, and antibody development applications.
- Inactive recombinant mouse Cathepsin C fragment for nonenzymatic studies.
- N-terminal 10xHis and C-terminal Myc tags for detection and purification.
- >95.0% purity by reducing SDS-PAGE.
- Lyophilized from 10 mM Tris-HCl, 1 mM EDTA, 6% trehalose (pH 8.0).
- Stable when stored lyophilized at -20°C; reconstituted stability: 4°C for 1 week or -20°C with carrier.
- Approximate molecular weight 16-20 kDa.
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Medchemexpress LLC Cloxiquine (5-Chloro-8-quinolinol) | 130-16-5 | 99.9% | 25 G
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Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal, and antiamoebic agent. It can be used for the research of tuberculosis and dermatoses, and suppresses the growth and metastasis of melanoma cells through the activation of PPARγ.
- Antibacterial, antifungal, and antiamoebic properties
- Suitable for tuberculosis and dermatoses research
- Suppresses growth and metastasis of melanoma cells
- Exhibits antituberculosis activities with low MICs
- Inhibits migration of B16F10 and A375 cells
- Suppresses glycolysis in B16F10 cells
- Proven to suppress tumor growth in mouse models
- Demonstrated to suppress tumor metastasis in mouse models
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Medchemexpress LLC Veratrole | 91-16-7 | 99.5% | 500 G
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Veratrole (1,2-Dimethoxybenzene) is a compound found in plants that attracts pollinators, playing a vital role in plant reproduction and interactions. It can also be demethylated by cytochrome P-450 in *Streptomyces setonii*. This product is for research use only.
- Molecular weight: 138.17
- Formula: C8H10O2
- Appearance: solid below 15°C, liquid above 15°C
- Color: colorless to light yellow
- SMILES: COC1=CC=CC=C1OC
- Structure classification: others
- Initial source: plants including Leguminosae Glycine soya, Leguminosae Cyamopsis tetragonoloba (L.) Taub., and Compositae
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: store at room temperature for 3 years; in solvent: -80°C for 2 years, -20°C for 1 year
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Medchemexpress LLC Cathepsin Z (mouse) recombinant protein, C-terminal His tag | >95.0% | 10 UG
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Recombinant mouse Cathepsin Z (CTSZ) produced in HEK293 cells with a C-terminal His tag. Supplied as a lyophilized powder for biochemical assays and reagent applications; the proenzyme requires activation in acid reducing buffer for functional studies.
- Expression system: HEK293 cells.
- Tag: C-terminal His tag for purification and detection.
- Purity greater than 95% by reducing SDS-PAGE.
- Form: lyophilized powder formulated from PBS, pH 7.4.
- Endotoxin less than 1 EU/μg.
- Molecular weight approximately 38 kDa and glycosylated.
- Activity measured at 715.46 pmol/min/μg after activation.
- Storage: stable at -20°C; aliquot and store at -80°C for long term.
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Alkali Scientific Benzamidine Hydrochloride, 100 G
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Benzamidine Hydrochloride is a high-purity protease inhibitor provided in a 100g package, ideal for use in biochemical and molecular biology applications. As a potent inhibitor of serine proteases, it is frequently used to prevent enzymatic degradation in protein purification and enzyme activity assays. Benzamidine Hydrochloride is commonly employed in laboratory workflows to inhibit trypsin, thrombin, and other proteases during protein analysis, ensuring that protein samples remain intact and active. This reagent is widely used in cell culture, biochemical research, and the preparation of cell lysates and other protein-rich samples where protease activity must be suppressed.
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Ambeed 1HInden2 3H one
1H-Inden-2(3H)-one, 615-13-4, 98%
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Medchemexpress LLC 4-[[[4-[5-chloro-2-[[4-(2-methoxyethylamino)cyclohexyl]amino]-4-pyridinyl]-1,3-thiazol-2-yl]amino]... | 2247481-21-4 | MFCD31807311 | 98.7% | 505.08 | C24H33ClN6O2S | 1mg
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JSH-150 is a highly selective and potent CDK9 inhibitor with an IC50 of 1 nM
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Medchemexpress LLC Bromophenol blue | 115-39-9 | MFCD00005875 | 5 G
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Bromophenol blue is an acid phthalein dye utilized as a tracking dye for electrophoresis. It serves as a pH indicator with a transition range of pH 3 to 4.6. Moreover, it is used as a sensor for the determination of various compounds, including ammonia, drugs, proteins, and amino acids.
- Functions as a pH indicator with a transition range of pH 3 to 4.6.
- Serves as a sensor for determining compounds like ammonia, drugs, proteins, and amino acids.
- Exhibits strong absorbance at 610 nm when bound to proteins.
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Medchemexpress LLC Chitobiose dihydrochloride | 115350-24-8 | 10 MG
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Chitobiose dihydrochloride is an orally active chitosan oligosaccharide with a degree of polymerization of 2. It demonstrates hepatoprotective activity and can counteract CCl4-induced elevation of plasma aspartate transaminase and alanine transaminase activities in rats, making it useful in the research of carbon tetrachloride-induced acute hepatotoxicity.
- Orally active chitosan oligosaccharide
- Demonstrates hepatoprotective activity
- Can counteract CCl4-induced elevation of plasma aspartate transaminase and alanine transaminase activities
- Used in research of carbon tetrachloride-induced acute hepatotoxicity
- Significantly reduces CCl4-induced acute hepatotoxicity in male Wistar rats
- Suppresses lipid peroxidation and hepatic transaminase elevation
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Medchemexpress LLC Slingshot inhibitor D3 | 1715076-35-9 | 99.5% | 461.55 g·mol⁻¹ | C25H19NO4S2 | 10MM 1ML
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Slingshot inhibitor D3 is a potent, selective, reversible, and competitive inhibitor of Slingshot phosphatases (SSH family) used in biochemical and cell-based assays to probe SSH function. It is supplied as a ready-to-use 10 mM solution in DMSO and is intended for inhibition studies, mechanistic assays, and compound screening.
- Potent inhibition of Slingshot 1 (IC50 = 3 μM) and activity against Slingshot 2 (Ki = 3.9 μM).
- Supplied as a 10 mM solution in DMSO, 1 mL vial ready for use.
- High purity (~99.5%) suitable for research applications.
- Molecular weight 461.55 g·mol⁻¹ and formula C25H19NO4S2.
- Useful for biochemical and cell-based assays to study Slingshot-mediated dephosphorylation pathways.
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Medchemexpress LLC Phospho-p95/NBS1 (Ser343) Antibody (YA165) | 10 UL
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This product is an antibody named Phospho-p95/NBS1 (Ser343) Antibody (YA165), identified by the catalog number HY-P80473. It is a Rabbit-derived, non-conjugated IgG monoclonal antibody that targets Phospho-p95/NBS1 (Ser343). The antibody is suitable for applications such as Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunohistochemistry-Paraffin (IHC-P), and Immunoprecipitation (IP), and shows reactivity with Human and Mouse samples.
- Targets Phospho-p95/NBS1 (Ser343).
- Rabbit-derived, non-conjugated IgG monoclonal antibody.
- Suitable for WB, ICC/IF, IHC-P, and IP.
- Reacts with human and mouse samples.
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