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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784832 Z-GLYCINOL 500G
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Medchemexpress LLC 1-Heptadecanoyl-2-hy | 25MG
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1-Heptadecanoyl-2-hy | 25MG
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Medchemexpress LLC 4-Piperidinone, 2,2,6,6-tetramethyl- | 826-36-8 | 155.24 | 10 G
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Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides, and photostabilizers for polymers. It has oral activity and can induce acute liver failure (ALF) in rats.
- Used as an intermediate in chemical synthesis.
- Exhibits oral activity.
- Can induce acute liver failure in rats.
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eMolecules 77-86-1 | Tris(hydroxymethyl)aminomethane | Combi-Blocks | MFCD00004679 | 121.136 | C4H11NO3 | 95.000 | NC(CO)(CO)CO | 100g | 290698042
Tris(hydroxymethyl)aminomethane | Combi-Blocks | 77-86-1 | MFCD00004679 | 121.136 | C4H11NO3 | 95.000 | NC(CO)(CO)CO | 100g | 290698042
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eMolecules 13139-17-8 | N-(Benzyloxycarbonyloxy)succinimide | Combi-Blocks | MFCD00005513 | 249.222 | C12H11NO5 | 98.000 | O=C(OCc1ccccc1)ON1C(=O)CCC1=O | 100g | 290689119
N-(Benzyloxycarbonyloxy)succinimide | Combi-Blocks | 13139-17-8 | MFCD00005513 | 249.222 | C12H11NO5 | 98.000 | O=C(OCc1ccccc1)ON1C(=O)CCC1=O | 100g | 290689119
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784542 BMIMCL 25G
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eMolecules EMOLECULES INC
5000841787 CYTARABINE 25G
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eMolecules EMOLECULES INC
5000841654 N-HYDROXYSULFOSUCCINIMIDE 5G
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Bioss CDV Fusion glycoprotein F0 Mon
CDV Fusion glycoprotein F0 Monoclonal Antibody
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Ambeed AMBEED
5000847145 CHLORPHENESIN 500G
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Ambeed AMBEED
5000847144 BROMO TRIPHENYLPHOSPHIN 100MG
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Medchemexpress LLC PROTAC BCR-ABL1 ligand 1 | 2489876-34-6 | 99.2% | 250 MG
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PROTAC BCR-ABL1 ligand 1, also known as compound GMB-475, is a PROTAC ligand that allosterically targets the BCR-ABL1 protein. It recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1. It demonstrates cell proliferation inhibition with IC50 values ranging from 0.37 μM to 1.98 μM for different BCR-ABL1 cell types and induces the degradation of BCR-ABL1 and c-ABL1, inhibiting downstream signaling via the STAT5 pathway in a dose- and time-dependent manner.
- Targets the BCR-ABL1 protein allosterically
- Recruits the E3 ligase Von Hippel-Lindau
- Leads to ubiquitination and degradation of BCR-ABL1
- Induces degradation of BCR-ABL1 and c-ABL1
- Inhibits downstream signaling via the STAT5 pathway
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Medchemexpress LLC BSJ-02-162 | 2139329-47-6 | 98.1% | C43H49N11O7 | 1 ML
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BSJ-02-162, also known as CDK4/6-IN-11, is a potent PROTAC CDK4/6 degrader. It is specifically designed with a thalidomide-based E3 ligase ligand, Palbociclib as a target protein ligand, and a PROTAC linker, making it suitable for targeted protein degradation studies.
- Potent PROTAC CDK4/6 degrader
- Composed of a thalidomide-based E3 ligase ligand
- Includes a target protein ligand
- Features a PROTAC linker
- Available in solid and solution formats
- Soluble in DMSO
- Store powder at -20°C for 3 years, 4°C for 2 years
- Store in solvent at -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784543 N-BENZOYLIMIDAZOLE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784535 5-BROMO-3-FLUOROPICO 25G
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