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Filtered Search Results
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | ≥97.0% | 1 G
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Bromo-PEG1-CH2COOH is a PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTAC linker for synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000693145 NAPHTHORESORCINOL 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000693033 SCOPOLAMINE HYDROCH 25MG
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STA PHARMACEUTICAL US LLC Fmoc-(S)-2-amino-6,6,6-Triflurohexanoic acid | 50 g | CAS 2230472-61-2 | InChIKey RVXLFAQYYCBCAT-SFHVURJKSA-N
Fmoc-(S)-2-amino-6,6,6-Triflurohexanoic acid is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2230472-61-2
- MDL: No data
- InChIKey: RVXLFAQYYCBCAT-SFHVURJKSA-N
- Molecular Weight: 407.389
- Molecular Formula: C21H20F3NO4
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6,6,6-trifluorohexanoic acid
- SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@H](C(O)=O)CCCC(F)(F)F
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Medchemexpress LLC 3,4-(Methylenedioxy)benzonitrile | 4421-09-4 | MFCD00005820 | 99.9% | 25g
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Piperonylonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]
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Medchemexpress LLC Melamine | 108-78-1 | MFCD00006055 | 100.0% | 126.12 g/mol | C3H6N6 | 100g
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Melamine is an orally active inducer of Apoptosis Melamine induces animal disease models Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function Melamine also has neurotoxicity and nephrotoxicity Melamine induces cognitive impairment and acute kidney injury models Melamine can also be used to induce bladder cancer and urinary stone models[1][2][3][4][5][6]
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Medchemexpress LLC Melamine | 108-78-1 | MFCD00006055 | 99.9% | 126.12 g/mol | C3H6N6 | 25g
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Melamine is an orally active inducer of Apoptosis Melamine induces animal disease models Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function Melamine also has neurotoxicity and nephrotoxicity Melamine induces cognitive impairment and acute kidney injury models Melamine can also be used to induce bladder cancer and urinary stone models[1][2][3][4][5][6]
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Medchemexpress LLC Bis-NH2-PEG2 | 929-59-9 | 99.8% | 1 G
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Bis-NH2-PEG2, also known as PROTAC Linker 19, is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This product is strictly for research purposes and is not intended for patient use. PROTACs are innovative molecules that function by recruiting target proteins to E3 ubiquitin ligases, leading to their ubiquitination and subsequent degradation by the proteasome system.
- Used in the synthesis of PROTACs
- For research purposes only
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC OARV-771 | 2683008-37-7 | 98.8% | C49H59ClN8O8S2 | 10MG
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OARV-771 is a VHL-based BET degrader (PROTAC) that induces proteasomal degradation of BET family proteins BRD2, BRD3, and BRD4. It demonstrates low-nanomolar degradation potency in cellular assays and is supplied as a solid with high chemical purity for research use.
- Low-nanomolar degradation potency (DC50: Brd2 ~1 nM, Brd3 ~4 nM, Brd4 ~6 nM).
- VHL-based PROTAC mechanism for targeted protein degradation.
- Improved cell permeability for cellular studies.
- High chemical purity suitable for biochemical and cell-based assays.
- Solid form for convenient handling and formulation.
- Recommended sealed cold storage to maintain stability.
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eMolecules EMOLECULES INC
5000490733 3-BROMO-2 5-DIFLUOROPYRIDIN 5G
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Accela Chembio Inc 3 | 5-dibromo-4-hydroxybenzoic Acid | 100g | 3337-62-0 | MFCD00002548 | 97+% | Shelf Life: 1440 Days | Light Sensitive
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3 | 5-dibromo-4-hydroxybenzoic Acid | 100g | 3337-62-0 | MFCD00002548 | 97+% | Shelf Life: 1440 Days | Light Sensitive
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Medchemexpress LLC Todralazine hydrochloride | 3778-76-5 | 99.9% | 5 MG
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Todralazine hydrochloride is an anti-hypertensive agent that acts as a β2AR blocker, possessing antioxidant and free radical scavenging activity. It is intended for research use only and not for sale to patients.
- Anti-hypertensive agent
- Acts as a β2AR blocker
- Possesses antioxidant activity
- Possesses free radical scavenging activity
- Intended for research use only
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Medchemexpress LLC Novobiocin (Sodium) | 1476-53-5 | 99.1% | 1 ML
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Novobiocin sodium is a potent and orally active antibiotic that functions as a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. It shows potential for research into highly beta-lactam-resistant pneumococcal infections and demonstrates anti-orthopoxvirus activity. This product is intended for research use only.
- Potent and orally active antibiotic
- Acts as a DNA gyrase inhibitor
- Functions as a heat shock protein 90 (Hsp90) antagonist
- Useful in research for highly beta-lactam-resistant pneumococcal infections
- Exhibits anti-orthopoxvirus activity
- Inhibits ATP binding to gyrase B
- Induces caspase-3/7 enzyme-dependent apoptosis in K562, HL60, and Mutz-2 cells
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Medchemexpress LLC GSK 3008348 hydrochloride | 1629249-40-6 | 99.9% | 524.11 | 50 MG
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GSK 3008348 hydrochloride is a small molecule antagonist of integrin αvβ6. It targets the αvβ6 integrin, inhibits TGF-β activation, and can alleviate the fibrotic process. It also prevents the binding of the foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor, inhibiting virus entry. GSK 3008348 hydrochloride can be used for research on pulmonary fibrosis and various types of cancer.
- Small molecule antagonist of integrin αvβ6.
- Inhibits TGF-β activation.
- Alleviates the fibrotic process.
- Prevents binding of foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor.
- Inhibits viral entry.
- Used for research on pulmonary fibrosis and various types of cancer.
- Antagonizes integrin αvβ6 with high affinity.
- Suppresses FMDV RNA replication and virus production.
- Decreases TGF-β1-activated procollagen I production.
- Inhibits TGF-β-induced phosphorylation of ERK1/2 and STAT3.
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eMolecules EMOLECULES INC
5000490836 POTASSIUM TRIMETHYLSILANO 100G
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