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Filtered Search Results
Medchemexpress LLC Norverapamil (hydrochloride) | 67812-42-4 | MFCD00078605 | 99.8% | 477.04 g·mol⁻¹ | C26H37ClN2O4 | 1 MG
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Norverapamil hydrochloride is the monohydrochloride salt of an N-demethylated metabolite of verapamil. It acts as an L-type calcium channel blocker and an inhibitor of P-glycoprotein (P-gp), and is used in pharmacological and transporter research.
- Acts as an L-type calcium channel blocker.
- Inhibits P-glycoprotein (P-gp) function.
- Suitable for in vitro pharmacology and transporter studies.
- Supplied as a solid or as a DMSO solution for experimental use.
- High reported purity (99.8%).
- Molecular weight 477.04 g·mol⁻¹; formula C26H37ClN2O4.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429057 CHO MAGNETIC BEADS 1ML
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eMolecules N-3-BUTYNYLPHTHALIMIDE 25G
5000166041 N-3-BUTYNYLPHTHALIMIDE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000366440 CITRONELLOL 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000362296 XP-524 10MM 1ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000363316 MTR-106 25MG
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Apexbio Technology LLC NPS-1034 1221713-92-3 25mg
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NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000447380 N-BENZYLHYDROXYLAMIN 1KG
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Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 528.56 g/mol | C30H39Cl2N3O | 50 MG
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(1S,2S)-2-PCCA hydrochloride is the hydrochloride salt of the (1S,2S) diastereomer of 2-PCCA, a small-molecule ligand used to probe GPR88 receptor biology. It is intended for research use in biochemical and cell-based assays. Physical data: C30H39Cl2N3O; MW 528.56; CAS 1609563-70-3.
- Hydrochloride salt form for improved solubility in DMSO.
- Tool compound for investigating GPR88 receptor signaling in vitro.
- Reported activity: related compound inhibits GPR88-mediated cAMP production (EC50 116 nM in HEK293 cells).
- High solubility in DMSO (100 mg/mL; may require ultrasonic).
- Suitable for biochemical, cellular, and analytical applications.
- Recommended storage to preserve stability: 4°C for solid; in solution, -80°C up to 6 months.
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Cambridge Isotope Laboratories 2 2 3 3 4 5 5 6 6-NonaBDE (BDE-208) (13C12 99%) 50 ug/mL in nonane 1 2 mL
2 2 3 3 4 5 5 6 6-NonaBDE (BDE-208) (13C12 99%) 50 ug/mL in nonane 1 2 mL
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eMolecules Ambeed / 236-Trifluorophenol / 5g / 552763582 / A984572 / / 113798-74-6 / MFCD00061214 / 148.084 / C6H3F3O
Ambeed / 236-Trifluorophenol / 5g / 552763582 / A984572 / / 113798-74-6 / MFCD00061214 / 148.084 / C6H3F3O
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429825 ANTICANCER AGENT 265 10G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000425641 PHM-27 HUMAN 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000385220 ATOMOXETINE HYDROCH 50MG
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Apexbio Technology LLC Bazedoxifene HCl 198480-56-7 10mM (in 1mL DMSO)
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Bazedoxifene HCl (198480-56-7) is a non-steroidal selective estrogen receptor modulator (SERM) targeting estrogen receptor subtypes ER and ER It is designed to bind ERs thereby modulating estrogen receptor-mediated signaling pathways Bazedoxifene HCl exerts its biological activity primarily by antagonizing ER -mediated transcriptional activity thereby inhibiting estradiol-induced cell proliferation In cell-based studies Bazedoxifene HCl demonstrates inhibition of cell proliferation in human breast cancer (MCF-7) ovarian (CHO) hepatic (HepG2) and neuronal (GT1-7) cell lines The compound exhibits binding affinities (Ki) of 26 nM for ER and 99 nM for ER Based on these pharmacological properties Bazedoxifene HCl holds research potential in osteoporosis and estrogen receptor-mediated diseases including breast ovarian and uterine cancers
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