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Filtered Search Results
Apexbio Technology LLC Methenamine 1g
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B1972 is a small molecule designed for biomedical research applications It modulates specific cellular signaling pathways thereby influencing target protein function at the molecular level B1972 has been utilized in studies investigating pathway regulation cell proliferation and disease models where pathway dysregulation occurs Its application enables the elucidation of signaling mechanisms and supports the development of targeted therapeutic strategies in preclinical research contexts
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Medchemexpress LLC Pf-07038124 hydrochloride | 2415317-57-4 | 99.3% | 363.64 g/mol | C18H23BClNO4 | 5 MG
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PF-07038124 hydrochloride is the hydrochloride salt of a selective phosphodiesterase 4 (PDE4) inhibitor supplied for laboratory research into inflammatory skin diseases and immune signaling pathways. Intended for research use only; not for human or clinical use.
- High purity suitable for biochemical and cellular assays.
- Potent inhibition of PDE4B2 (IC50 ≈ 0.5 nM).
- Demonstrated cytokine inhibition of IL-13, IL-4, and IFN-γ in reported assays.
- Available in small milligram quantities for early-stage studies.
- Hydrochloride salt form improves solubility for aqueous assays.
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eMolecules EMOLECULES INC
5000189504 METHOXYMETHYLTRIPHENYLPHO 5G
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eMolecules EMOLECULES INC
5000189502 METHOXYMETHYLTRIPHENYLP 100G
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eMolecules EMOLECULES INC
5000189503 METHOXYMETHYLTRIPHENYLP 500G
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eMolecules 1-METHYLCYCLOPROPANAMINE H 10G
5000189524 1-METHYLCYCLOPROPANAMINE H 10G
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Cambridge Isotope Laboratories 2 2 4 4 5-PentaBDE (BDE-99) (13C12 99%) 50 ug/mL in nonane 1 2 mL
2 2 4 4 5-PentaBDE (BDE-99) (13C12 99%) 50 ug/mL in nonane 1 2 mL
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Medchemexpress LLC L-citronellol | 7540-51-4 | MFCD00063214 | 99.5% | 156.27 | C10H20O | 100 G
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L-citronellol is an analytical standard of the monoterpenoid alcohol (S)-3,7-dimethyloct-6-en-1-ol supplied for research and analytical applications. The material is provided with supporting documentation (COA, SDS) and should be stored under the conditions specified in the certificate of analysis. For research use only.
- Purity 99.5%.
- Molecular formula C10H20O.
- Molecular weight 156.27 g/mol.
- CAS number 7540-51-4.
- Intended for research and analytical applications.
- Supplied with certificate of analysis and safety data sheet.
- Available sizes listed by manufacturer up to 5 g (see COA for batch packaging).
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Medchemexpress LLC EPIGEN HUMAN E. CO 10UG
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5000176720 EPIGEN HUMAN E. CO 10UG
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Medchemexpress LLC N'-[3-[[5-bromo-2-[3-(pyrrolidine-1-carbonylamino)anilino]pyrimidin-4-yl]amino]propyl]-2,2-dimethylpropanediamide | 702676-93-5 | MFCD12922516 | 99.4% | 547.45 g·mol⁻1 | C23H31BrN8O3 | 1 MG
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BX-320 is a selective, ATP-competitive, orally active small-molecule inhibitor of PDK1 for preclinical research. It inhibits PDK1 with an IC50 of 30 nM, blocks PDK1/Akt signaling, induces apoptosis in tumor cells, and has demonstrated antiproliferative and antitumor activity in cell-based and animal models.
- Selective ATP-competitive PDK1 inhibitor (IC50 30 nM).
- Blocks PDK1/Akt signaling and induces apoptosis in tumor cells.
- Demonstrates antiproliferative activity in cell assays and efficacy in in vivo tumor models.
- Exhibits off-target activity against Chk1, c-Kit, KDR, PKA, CDK2, GSK3β, and PKC at micromolar concentrations.
- High purity (99.4%).
- Molecular weight 547.45 g·mol⁻1; formula C23H31BrN8O3.
- Store solid at -20°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC Apolipoprotein E/APOE3 protein, human (HEK293, hFc) | >95.0% | 50UG
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Recombinant human apolipoprotein E (APOE3) with an N-terminal human Fc tag, expressed in HEK293 cells and supplied lyophilized. The protein is formulated in PBS with 8% trehalose, has >95% purity, and a reported molecular weight of 60-70 kDa. It is intended for research use and has demonstrated binding to human TREM2 in SPR assays.
- Recombinant human APOE3 with N-terminal hFc tag.
- Expressed in HEK293 cells for human-like post-translational modifications.
- Lyophilized from PBS with 8% trehalose for improved stability.
- Purity >95% as determined by reducing SDS-PAGE.
- Demonstrated binding to human TREM2 in SPR assays.
- Stable when stored frozen; aliquot and store at -20°C or -80°C for long-term storage.
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Apexbio Technology LLC Difloxacin HCl 91296-86-5 10mM (in 1mL DMSO)
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Difloxacin HCl (CAS 91296-86-5) is a small-molecule inhibitor targeting DNA gyrase and topoisomerase IV It is designed to interfere with DNA gyrase-mediated DNA synthesis thereby inhibiting bacterial DNA replication and cell division Difloxacin HCl exerts its biological activity primarily through inhibition of DNA gyrase and topoisomerase IV In cultured human neuroblastoma cells exhibiting multidrug resistance associated protein (MRP)-mediated chemoresistance difloxacin HCl (50 g/ml) increases cell sensitivity to MRP substrates including doxorubicin vincristine daunorubicin and potassium antimony tartrate indicating reversal of the drug-resistance phenotype Based on these pharmacological properties difloxacin HCl holds research potential in antimicrobial susceptibility testing and studies of multidrug resistance reversal
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Medchemexpress LLC Dibenzylamine | 103-49-1 | MFCD00004770 | 99.9% | 197.28 g/mol | C14H15N | 500g
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Dibenzylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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Cambridge Isotope Laboratories Octabromodibenzofuran (13C12 99%) 5 ug/mL in nonane toluene (70 30) 1 2 mL
Octabromodibenzofuran (13C12 99%) 5 ug/mL in nonane toluene (70 30) 1 2 mL
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Cambridge Isotope Laboratories Octabromodibenzofuran (13C12 99%) 5 ug/mL in nonane toluene (70 30) 4 x 1 2 mL
Octabromodibenzofuran (13C12 99%) 5 ug/mL in nonane toluene (70 30) 4 x 1 2 mL
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