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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378143 SSRNA42 SODIUM 1MG
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Medchemexpress LLC N,N'-Carbonyldiimidazole | 530-62-1 | 99.9% | C7H6N4O | 100 G
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N,N'-Carbonyldiimidazole is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. It is also used as a coupling agent and a peptide synthesis reagent.
- Functions as a highly reactive carboxylating reagent
- Activates hydroxyl groups to form reactive carbonyl groups
- Can be used as a coupling agent
- Can be used as a peptide synthesis reagent
- Mediates conjugation of ovalbumin with magnetite nanoparticles for vaccine delivery
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Aobchem AOBCHEM
5000865323 2-BROMO-3 4-DIFLUOROPHENOL 1G
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Medchemexpress LLC Neurotoxin Inhibitor | 951571-70-3 | 99.0% | 346.41 | 1 ML
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Neurotoxin Inhibitor is a neurotoxin inhibitor that promotes the expression of DJ-1 protein, reduces the level of oxidative stress, and thereby protects dopaminergic neurons. It can be used for the study of Parkinson's disease.
- Promotes the expression of DJ-1 protein.
- Reduces the level of oxidative stress.
- Protects dopaminergic neurons.
- Can be used for the study of Parkinson's disease.
- Dose-dependently upregulates the expression of DJ-1 protein in SH-SY5Y cells and primary cortical neurons of mice.
- Effectively alleviates excessive oxidative stress in SH-SY5Y cells treated with MPP⁺.
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eMolecules O-DIPHENYLPHOSPHINYLHYD 100G
5000223652 O-DIPHENYLPHOSPHINYLHYD 100G
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Medchemexpress LLC Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) | FZD7 receptors antagonist | 2247635-23-8 | 99.6% | 1796.05 | 1 MG
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Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors. It selectively binds to the FZD7 CRD subclass, altering the conformation of the CRD and the architecture of its lipid-binding groove. This compound impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids.
- Potent peptide antagonist of FZD7 receptors
- Selectively binds to FZD7 CRD subclass
- Alters CRD conformation and lipid-binding groove architecture
- EC50 values: 58 nM (human FZD7 CRD) and 34 nM (mouse FZD7 CRD)
- Impairs Wnt signaling with an IC50 value of 100 nM in HEK293-TB cells
- Blocks WNT3A-mediated stabilization of β-catenin in mouse L cells with an IC50 value of 50 nM
- Disrupts LGR5+ stem cell function in LGR5-GFP+ stem cells at 200 μM over 48 hours
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703126 N N-DIETHYLBENZAMIDE 25G
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5000703150 DSP CROSSLINKER 25G
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5000703422 QUERCETIN 100G
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Medchemexpress LLC Hexacosanoic acid-d4-1 | 1194984-85-4 | 98.0% | 400.71 | 10 MG
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Hexacosanoic acid-d4 is the deuterium-labeled version of Hexacosanoic acid. It is a very long-chain fatty acid. Abnormally elevated levels of Hexacosanoic acid are closely associated with various diseases, such as X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for quantitation during drug development process.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369770 ELLIPTICINE HYDROCH 100MG
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5000376961 ILORASERTIB HYDROCH 10MM 1ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369769 TUG-770 100MG
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5000369665 ELLIPTICINE HYDROCH 50MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369427 CRT0066101 DIHYDROC 10MM 1ML
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