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Filtered Search Results
Bioss Bad Ser-26 Phosphospecific An
Bad Ser-26 Phosphospecific Antibody
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TARGETMOL CHEMICALS INC SKLB-163 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SKLB-163 acts by downregulating RhoGDI activating JNK-1 signaling pathway and caspase-3 and reducing phosphorylated Akt and p44/42 MAPK. purity: 98%
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Apexbio Technology LLC Butenafine HCl 101827-46-7 10mM (in 1mL DMSO)
Butenafine HCl (CAS 101827-46-7) is a small-molecule inhibitor targeting squalene epoxidase It is designed to inhibit this enzyme thereby disrupting fungal sterol biosynthesis Butenafine HCl exerts its biological activity primarily through inhibition of squalene epoxidase leading to impaired ergosterol synthesis and accumulation of squalene which disrupts fungal cell membrane integrity and results in cell death In biochemical studies Butenafine HCl demonstrates inhibitory activity with reported IC50 values ranging from approximately 0 03 M to 0 1 M depending on fungal species and experimental conditions Based on these pharmacological properties Butenafine HCl holds research potential in biomedical antifungal studies including investigations into fungal physiology antifungal efficacy and drug resistance mechanisms
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Apexbio Technology LLC Amitriptyline HCl 549-18-8 10mM (in 1mL DMSO)
Amitriptyline HCl (CAS 549-18-8) is a tricyclic compound that modulates multiple neurotransmitter systems It acts as an inhibitor at serotonin and norepinephrine receptors demonstrating potent activity with IC50 values of 3 45 nM and 13 3 nM respectively Amitriptyline also exhibits notable affinity for 5-HT4 (IC50 7 31 nM) 5-HT2 (IC50 235 nM) and sigma-1 receptors (IC50 287 nM) indicating a broad spectrum of receptor interactions This pharmacological profile supports its application in neuropharmacological research including studies of synaptic transmission antidepressant mechanisms and receptor signaling pathways
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eMolecules 100868-49-3 | 5-AMINO-2,3-DICHLOROPHENOL | AstaTech | MFCD28786401 | 178.010 | C6H5Cl2NO | 95.000 | Nc1cc(O)c(Cl)c(Cl)c1 | 1g | 495722671
5-AMINO-2,3-DICHLOROPHENOL | AstaTech | 100868-49-3 | MFCD28786401 | 178.010 | C6H5Cl2NO | 95.000 | Nc1cc(O)c(Cl)c(Cl)c1 | 1g | 495722671
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Apexbio Technology LLC L-798,106 244101-02-8 10mg
L-798 106 (CAS 244101-02-8) is a highly selective antagonist of the prostaglandin E2 (EP3) receptor Binding studies demonstrate a strong affinity for the EP3 receptor with a Ki of 0 3 nM while showing substantially reduced affinity for EP1 ( 5000 nM) EP2 ( 5000 nM) and EP4 (916 nM) receptors By selectively inhibiting EP3 receptor-mediated signaling L-798 106 is utilized to investigate the physiological and pathological roles of EP3 in various disease models and serves as a molecular tool in the preclinical evaluation of EP3-targeted therapeutic strategies
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Apexbio Technology LLC Diphenidol HCl 3254-89-5 10mM (in 1mL DMSO)
Diphenidol hydrochloride (CAS 3254-89-5) is a small molecule that acts as a nonselective antagonist of muscarinic acetylcholine receptors targeting subtypes M1 through M4 It also inhibits multiple voltage-gated ion channels including sodium (Na ) potassium (K ) and calcium (Ca ) channels thereby modulating neuronal excitability Diphenidol hydrochloride has demonstrated antiarrhythmic activity and is frequently employed in studies investigating the neurophysiological mechanisms underlying vertigo and the pathways involved in antiemetic responses Its polypharmacological profile makes it a suitable tool for research into neural signaling and emesis modulation
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Apexbio Technology LLC Terazosin HCl 70024-40-7 10mM (in 1mL DMSO)
Terazosin hydrochloride (CAS 70024-40-7) is a selective antagonist of alpha1-adrenergic receptors By inhibiting these receptors terazosin induces relaxation of smooth muscle in the prostate and bladder neck thereby reducing urinary outflow resistance It is widely utilized in biomedical research to study the modulation of alpha1-adrenergic signaling pathways and the pathophysiology of lower urinary tract symptoms particularly in the context of benign prostatic hyperplasia (BPH) Its mechanism supports investigations into autonomic regulation of smooth muscle function and the pharmacological management of urological disorders
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Selleck Chemical LLC VY-3-135-E1147-10MM/1ML
VY-3-135 a potent ACSS2 inhibitor with IC50 of 44 3 85 nM potently inhibits ACSS2 dependent fatty acid metabolism but has no effect on gene expression in tumors
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eMolecules 185804-34-6 | 5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid | Apollo Scientific | MFCD06409135 | 225.151 | C10H5F2NO3 | 95.000 | OC(=O)c1cnc2cc(F)cc(F)c2c1O | 1g | 562462449
5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid | Apollo Scientific | 185804-34-6 | MFCD06409135 | 225.151 | C10H5F2NO3 | 95.000 | OC(=O)c1cnc2cc(F)cc(F)c2c1O | 1g | 562462449
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eMolecules 84225-95-6 | Raclopride | Combi-Blocks, Inc. | MFCD02179386 | 347.240 | C15H20Cl2N2O3 | 95.000 | CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC | 1g | 603145042
Raclopride | Combi-Blocks, Inc. | 84225-95-6 | MFCD02179386 | 347.240 | C15H20Cl2N2O3 | 95.000 | CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC | 1g | 603145042
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Selleck Chemical LLC PS-48
PS-48 is an allosteric activator of phosphoinositide-dependent protein kinase-1 (PDK1)
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Pfaltz & Bauer Tetrachlorobisphenol A 500G | 79-95-8
Tetrachlorobisphenol A 500G | 79-95-8
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Bioss Enterococcus sp.
Enterococcus sp
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Bioss Xin Actin-binding Repeat-conta
Xin Actin-binding Repeat-containing Protein 1 XIRP1 Ser295 Antibody
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