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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703304 N-METHYLISATOIC ANHY 100G
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5000701014 N N-DIPHENYLACETAMID 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377402 MARTINOSTAT HYDROCH 100MG
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Medchemexpress LLC IITZ-01 | 1807988-47-1 | 98.18% | 482.51 | 1 ML
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IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ. For research use only.
- Potent lysosomotropic autophagy inhibitor.
- Single-agent antitumor activity.
- IC50 of 2.62 μM for PI3Kγ.
- Enhances autophagosomes formation in triple-negative breast cancer (TNBC) cell lines (MDA-MB-231 and MDA-MB-453) by increasing LC3-II levels time- and dose-dependently.
- Demonstrates potent autophagy inhibitory activity in other breast, lung, and colon cancer cells.
- Inhibits average breast tumor growth in triple-negative breast tumor models in mice.
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Ambeed AMBEED
5000867106 PHENYL GHB SODIUM 5GR
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eMolecules 107496-54-8 | 3,3-Difluorocyclobutanecarboxylic acid | Combi-Blocks, Inc. | MFCD08705857 | 136.098 | C5H6F2O2 | 97.000 | OC(=O)C1CC(F)(F)C1 | 500g | 848837360
3,3-Difluorocyclobutanecarboxylic acid | Combi-Blocks, Inc. | 107496-54-8 | MFCD08705857 | 136.098 | C5H6F2O2 | 97.000 | OC(=O)C1CC(F)(F)C1 | 500g | 848837360
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BIOHIPPO
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5000858835 HUMAN CYAD-02 BIOSIMILAR
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![Apexbio Technology LLC HBcAg [Hepatitis B virus] (18-27) 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096656.png-250.jpg)
Apexbio Technology LLC HBcAg [Hepatitis B virus] (18-27) 1mg
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HBcAg Hepatitis B virus 18-27 is a viral antigen derived from the hepatitis B virus (HBV) core region HBcAg is produced during active viral replication and serves as a marker for intracellular HBV presence Detection and quantitation of HBcAg enable investigation of viral replication mechanisms and monitoring of HBV infection status Based on these properties HBcAg Hepatitis B virus 18-27 holds research potential in immunological assays vaccine studies antiviral agent evaluation and studies of host-virus interactions and immune modulation
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Apexbio Technology LLC Diphenidol HCl 3254-89-5 10mM (in 1mL DMSO)
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Diphenidol hydrochloride (CAS 3254-89-5) is a small molecule that acts as a nonselective antagonist of muscarinic acetylcholine receptors targeting subtypes M1 through M4 It also inhibits multiple voltage-gated ion channels including sodium (Na ) potassium (K ) and calcium (Ca ) channels thereby modulating neuronal excitability Diphenidol hydrochloride has demonstrated antiarrhythmic activity and is frequently employed in studies investigating the neurophysiological mechanisms underlying vertigo and the pathways involved in antiemetic responses Its polypharmacological profile makes it a suitable tool for research into neural signaling and emesis modulation
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Apexbio Technology LLC Valnemulin HCl 133868-46-9 10mM (in 1mL DMSO)
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Valnemulin HCl (CAS 133868-46-9) is a small-molecule inhibitor targeting bacterial protein synthesis It is designed to inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit thereby disrupting peptide bond formation and bacterial growth Valnemulin HCl exerts its biological activity primarily through specific binding to the peptidyl transferase region within the 50S ribosomal subunit In experimental animal models valnemulin HCl demonstrates inhibitory effects on Mycoplasma bovis proliferation in calf lung tissues with reported IC50 values against various bacterial isolates ranging from approximately 0 03 to 0 5 g/mL depending on the bacterial strain Based on these pharmacological properties valnemulin HCl holds research potential in the management of bacterial infections including applications in epizootic rabbit enteropathy and respiratory diseases in livestock
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Apexbio Technology LLC Butenafine HCl 101827-46-7 10mM (in 1mL DMSO)
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Butenafine HCl (CAS 101827-46-7) is a small-molecule inhibitor targeting squalene epoxidase It is designed to inhibit this enzyme thereby disrupting fungal sterol biosynthesis Butenafine HCl exerts its biological activity primarily through inhibition of squalene epoxidase leading to impaired ergosterol synthesis and accumulation of squalene which disrupts fungal cell membrane integrity and results in cell death In biochemical studies Butenafine HCl demonstrates inhibitory activity with reported IC50 values ranging from approximately 0 03 M to 0 1 M depending on fungal species and experimental conditions Based on these pharmacological properties Butenafine HCl holds research potential in biomedical antifungal studies including investigations into fungal physiology antifungal efficacy and drug resistance mechanisms
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587220 OMP25/SYNJ2BP F5X5O RABBIT MON
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587950 E-CADHERIN 24E10 RABBIT MONOCL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369770 ELLIPTICINE HYDROCH 100MG
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Medchemexpress LLC Pirarubicin hydrochloride | 95343-20-7 | MFCD01713157 | 99.1% | 664.10 g/mol | C32H38ClNO12 | 5 MG
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Pirarubicin hydrochloride is an anthracycline antineoplastic agent and a topoisomerase II inhibitor supplied as the hydrochloride salt. It is used in oncology research, particularly studies of solid tumors, and is provided as a high-purity solid or as a DMSO solution for laboratory applications.
- High purity 99.14%.
- Topoisomerase II inhibitor mechanism of action.
- Hydrochloride salt in solid form.
- Molecular weight 664.10 g/mol; formula C32H38ClNO12.
- Available in small research pack sizes and in DMSO solution.
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