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Filtered Search Results
Medchemexpress LLC G0-C14 | 1510653-27-6 | C106H216N10O10 | 25 MG
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G0-C14 is a cationic lipid-like compound, an alkyl-modified polyamidoamine (PAMAM) dendrimer. It is utilized in the preparation of macrophage-targeted nanoparticles (NPs) for agent and vaccine delivery.
- Strong entrapment of mRNA and pDNA with over 95% encapsulation efficiency.
- Appears as an oil.
- Colorless to light yellow in appearance.
- Purity of 98.0%.
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Medchemexpress LLC Cariprazine hydrochloride | 1083076-69-0 | 99.71% | 463.87 | 1 ML
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Cariprazine hydrochloride is a novel antipsychotic agent candidate that exhibits high affinity for D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). It is currently being investigated in various clinical trials for conditions such as Bipolar Disorder, Schizophrenia, and Major Depressive Disorder.
- High affinity for D3 (0.085 nM) and D2 (0.49 nM) receptors
- Moderate affinity for 5-HT1A receptor (2.6 nM)
- Antimanic properties
- Interferes with dopamine D2 receptor β-arrestin interactions
- Reduces ouabain-induced hyperactivity
- Available as a solution in DMSO
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Medchemexpress LLC 5-bromo-3-phenyl salicylic acid | 99514-99-5 | 98.0% | 293.11 g/mol | C13H9BrO3 | 5 MG
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5-Bromo-3-phenyl salicylic acid is a salicylic acid derivative for research use that acts as a selective inhibitor of human 20α-hydroxysteroid dehydrogenase (AKR1C1), with a reported Ki of 140 nM. The compound is supplied as a solid (off-white to light yellow) with a reported purity of about 98% and includes downloadable product documents (COA, SDS).
- Selective AKR1C1 inhibitor with Ki = 140 nM.
- Reported purity approximately 98.0%.
- Off-white to light yellow solid suitable for laboratory handling.
- Soluble in common organic solvents such as DMSO, ethanol, and DMF.
- Recommended storage: -20°C sealed; in solution -80°C up to 6 months or -20°C up to 1 month.
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Medchemexpress LLC ODN 4084-F sodium | 1934318-44-1 | DNA, d(P-thio)(C-C-T-G-G-A-T-G-G-G-A-A）, sodium salt | 1 MG
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ODN 4084-F sodium is a class B ('broadly-active') inhibitory ODN. It acts as a potent inhibitor of TLR9-induced B cells and macrophages. This product is a white to off-white solid.
- Class B ('broadly-active') inhibitory ODN
- Potent inhibitor of TLR9-induced B cells and macrophages
- Solid appearance
- White to off-white color
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eMolecules TRISHYDROXYMETHYLAMINOM 100G
5000169204 TRISHYDROXYMETHYLAMINOM 100G
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Medchemexpress LLC PF-06446846 hydrochloride | 1632250-50-0 | 99.4% | 470.35 | 25 MG
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PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). It inhibits PCSK9 by inducing the ribosome to stall around codon 34. This product is intended for research use only and is not sold to patients.
- Orally active and highly selective inhibitor of PCSK9 translation.
- Inhibits PCSK9 by inducing ribosome stalling.
- Lowers plasma PCSK9 and total cholesterol levels in a dose-dependent manner in animal models.
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Medchemexpress LLC Dorzolamide hydrochloride | 130693-82-2 | MFCD00884659 | 99.9% | C10H17ClN2O4S3 | 5 MG
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Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor. It effectively inhibits red blood cell CA-II with an IC50 value of 0.18 nM and CA-I with an IC50 of 600 nM. This compound also exhibits anti-tumor activity.
- Potent carbonic anhydrase II inhibitor
- IC50 values of 0.18 nM for red blood cell CA-II
- IC50 values of 600 nM for CA-I
- Exhibits anti-tumor activity
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eMolecules 5,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid | 171850-30-9 | MFCD00219832 | 1g
Combi-Blocks | 5,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid | 1g | 117560222 | SS-5536 | 97.000 | 171850-30-9 | MFCD00219832 | 258.050 | C10H5Cl2NO3
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Medchemexpress LLC Chloroneb 100g | 2675-77-6 | 100 G
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Chloroneb is an analytical/reference standard of the fungicide chloroneb (CAS 2675-77-6) supplied for laboratory use in qualitative and quantitative analyses by HPLC, GC, and MS. The 100 g laboratory pack is listed at 95.0% purity.
- Analytical reference standard for HPLC, GC, and MS.
- Intended for pesticide residue analysis and method development.
- Offered at 95.0% purity for the 100 g laboratory pack.
- Available in multiple lab-scale packaging to match analytical needs.
- Molecular weight 207.05 g/mol; chemical formula C8H8Cl2O2.
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Medchemexpress LLC HIF-1a-IN-2 hydroch 25mg | 25MG
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HIF-1a-IN-2 hydroch 25mg | 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370557 TOOS 25G
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Apexbio Technology LLC β-Interleukin I (163-171), human 106021-96-9 25mg
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beta-Interleukin I 163-171 human is a peptide fragment derived from human interleukin-1 (IL-1 ) It is utilized to investigate immune signaling pathways particularly those involved in inflammatory responses and T cell activation beta-Interleukin I 163-171 human exerts its biological activity by participating in the modulation of inflammatory signaling cascades relevant to immune system regulation Based on these pharmacological properties beta-Interleukin I 163-171 human holds research potential in the study of immune activation inflammation and associated signaling mechanisms in biomedical research
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Medchemexpress LLC 4-(3-chloro-4-cyanophenyl)-2-(2-((1R,2R)-2-hydroxy-2-methylcyclopropyl)amino)pyrimidi. | 1610677-37-6 | 99.6% | 535.04 g·mol⁻1 | C28H31ClN6O3 | 1 ML
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Luvixasertib hydrochloride is a potent, selective inhibitor of the TTK/Mps1 kinase with low-nanomolar biochemical potency and demonstrated in vitro anticancer activity. Supplied as the hydrochloride salt in a ready-to-use 10 mM DMSO solution, it is intended for preclinical kinase assays and cellular studies probing mitotic checkpoint biology.
- High potency: IC50 1.7 nM for TTK in vitro.
- Hydrochloride salt suitable for formulation and storage.
- Provided as a 10 mM solution in DMSO, 1 mL ready to use.
- High purity (99.63% by supplier analysis).
- Well characterized: CAS 1610677-37-6; molecular weight 535.04 g·mol⁻1.
- Applications: preclinical kinase inhibition and cellular mitotic checkpoint studies.
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Medchemexpress LLC Luvixasertib hydrochloride | 1610677-37-6 | 99.6% | 535.04 g/mol | C28H31ClN6O3 | 50 MG
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Luvixasertib hydrochloride is a selective, orally bioavailable small-molecule inhibitor of TTK/Mps1 used for preclinical research. It inhibits TTK/Mps1 with an in vitro IC50 of 1.7 nM and has demonstrated anticancer activity in cell-based studies.
- Selective TTK/Mps1 inhibition with IC50 of 1.7 nM.
- Orally bioavailable scaffold suitable for in vivo studies.
- Hydrochloride salt form improves solubility and handling.
- High reported purity (≈99.6%) for research reproducibility.
- Supplied in small research quantities for assay development and compound characterization.
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Medchemexpress LLC 2,4,5-trimethoxybenzaldehyde | 4460-86-0 | MFCD00003312 | 99.8% | 196.20 g/mol | C10H12O4 | 100 G
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Asaraldehyde (2,4,5-trimethoxybenzaldehyde) is a natural small-molecule reported to inhibit cyclooxygenase-2 (COX-2). It is supplied as a research/analytical standard with reported purity 99.83%, molecular weight 196.20 g/mol, and molecular formula C10H12O4. Literature cited by the supplier reports COX-2 inhibition with an IC50 of 100 μg/mL.
- Acts as a COX-2 inhibitor (reported IC50 100 μg/mL).
- High reported purity of 99.83%.
- Molecular weight 196.20 g/mol; formula C10H12O4.
- Provided as a research standard for biochemical and pharmacological assays.
- Available in laboratory-scale quantities, including 100 g packaging.
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