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Filtered Search Results
Apexbio Technology LLC Benzydamine HCl 132-69-4 10mM (in 1mL DMSO)
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Benzydamine hydrochloride (132-69-4) is a small-molecule inhibitor targeting cyclooxygenase (COX) enzymes It is designed to inhibit COX activity thereby reducing prostaglandin synthesis and regulating inflammatory pathways Benzydamine hydrochloride exerts its biological activity primarily through COX enzyme modulation and sodium channel blockade In cell-based assays benzydamine hydrochloride demonstrates prostaglandin production inhibition with an IC50 ranging from approximately 10 to 50 M depending on the experimental model Based on these pharmacological properties benzydamine hydrochloride holds research potential in investigating inflammatory pathways analgesic mechanisms and local anesthetic activity in vitro and in animal models
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Apexbio Technology LLC Cromolyn sodium 15826-37-6 5g
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Cromolyn sodium (CAS 15826-37-6) is a small molecule that functions as a mast cell membrane stabilizer It inhibits antigen-induced histamine release by preventing degranulation of sensitized mast cells Due to minimal gastrointestinal absorption cromolyn sodium is typically administered via inhalation in powder form Preclinical studies have demonstrated that cromolyn sodium suppresses both immediate and late-phase asthmatic responses and reduces the release of non-histamine chemical mediators Additionally it prevents ciliary transport impairment associated with bronchial provocation and can mitigate symptoms in exercise-induced asthma models These properties make cromolyn sodium a useful tool for investigating allergic and inflammatory mechanisms in respiratory research
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eMolecules EMOLECULES INC
5000192213 3-PYRIDINECARBOXALDEHYDE 50G
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Medchemexpress LLC Norverapamil hydrochloride ((±)-norverapamil hydrochloride) | 67812-42-4 | 99.8% | 477.04 g/mol | C26H37ClN2O4 | 25 MG
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Norverapamil hydrochloride is the N-demethylated metabolite of verapamil that functions as an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. It is provided as a high-purity research reagent for pharmacology, transporter studies, and drug-metabolism investigations.
- N-demethylated metabolite of verapamil.
- L-type calcium channel blocker activity.
- P-glycoprotein (P-gp) function inhibitor.
- High purity suitable for research applications.
- Soluble in water and DMSO, facilitating assay formulation.
- Recommended sealed storage at 4°C; solution stability at -80°C and -20°C.
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Medchemexpress LLC Aprinocarsen sodium | 331257-53-5 | 98.4% | 6435.2 (free acid) | 1 MG
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Aprinocarsen sodium (ISIS 3521) is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-α). This 20-mer oligonucleotide regulates cell differentiation and proliferation, showing potential as a chemotherapeutic compound for human cancers by inhibiting the growth of tumor cell lines in nude mice.
- Specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-α).
- Regulates cell differentiation and proliferation.
- Inhibits growth of human tumor cell lines in nude mice.
- Dose-dependently inhibits PKC-alpha in human bladder carcinoma (T-24) cells.
- Shows an IC50 value of 50-100 nM for PKC-α mRNA reduction.
- Well-tolerated in in vivo studies with no apparent acute toxicity.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428790 PENTAFLUOROPHENOL 100G
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Medchemexpress LLC Ecteinascidin 770 | 114899-80-8 | 99.8% | 770.85 g·mol⁻¹ | C40H42N4O10S | 25 MG
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Ecteinascidin 770 (ET-770) is a marine-derived tetrahydroisoquinoline alkaloid with potent cytotoxic and anticancer activity, commonly used as a research reagent for in vitro pharmacology and cell biology studies. The compound is supplied as a solid (white to yellow) and is typically prepared as DMSO stock solutions for cellular assays.
- Potent cytotoxic activity against multiple cancer cell lines (low nanomolar IC50s).
- High reported chemical purity suitable for research applications.
- Available in multiple small-scale quantities for assay development and screening.
- Stable when stored cold and protected from light; specific storage recommendations for solids and solutions.
- Provided with chemical identifiers and safety documentation for laboratory handling.
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Cambridge Isotope Laboratories EDTA (D16 98%) 0 1 g
EDTA (D16 98%) 0 1 g
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eMolecules CYCLOBUTANONE 100G
5000226094 CYCLOBUTANONE 100G
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eMolecules N-BENZYLOXYCARBONYLOXYS 100G
5000161524 N-BENZYLOXYCARBONYLOXYS 100G
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eMolecules Medchem Express / SKF-83566 / 5mg / 533802220 / HY-103430A / / 99295-33-7 / MFCD04975449 / 332.241 / C17H18BrNO
Medchem Express / SKF-83566 / 5mg / 533802220 / HY-103430A / / 99295-33-7 / MFCD04975449 / 332.241 / C17H18BrNO
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Medchemexpress LLC Carm1-in-3 dihydrochloride | C24H34Cl2N4O2 | 5 MG
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CARM1-IN-3 dihydrochloride (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07 μM for CARM1 and >25 μM for CARM3. This compound is a solid with a white to off-white appearance.
- Potent and selective CARM1 inhibitor
- IC50 for CARM1: 0.07 μM
- IC50 for CARM3: >25 μM
- Soluble in DMSO and H2O
- Appearance: solid, white to off-white
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Medchemexpress LLC 6-(4-methylpiperazin-1-yl)-3-naphthalen-2-yl-4-pyridin-4-ylpyridazine | 1628502-91-9 | 99.9% | 1 ML
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MW-150 is a selective, CNS-penetrant inhibitor of p38α mitogen-activated protein kinase (p38α MAPK). Supplied as a 10 mM solution in DMSO (1 mL), it has formula C24H23N5, molecular weight 381.47 g/mol, and high purity suitable for research applications.
- Selective inhibition of p38α MAPK.
- CNS penetrant and orally active in preclinical studies.
- High purity (99.9%) suitable for research.
- Supplied as a 10 mM solution in DMSO, 1 mL volume.
- Commonly used in neuroscience and inflammation research.
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eMolecules N-IODOSUCCINIMIDE 100G
5000169353 N-IODOSUCCINIMIDE 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428223 SDS-PAGE SAMPLE LOAD 5ML
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