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Filtered Search Results
Medchemexpress LLC 8-bromo-cAMP sodium salt | 76939-46-3 | MFCD00005844 | 99.9% | 430.08 | C10H10BrN5NaO6P | 25MG
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8-Bromo-cAMP sodium salt is a membrane-permeable analog of cyclic adenosine monophosphate (cAMP) that activates cyclic AMP-dependent protein kinase (PKA). It is used in biochemical and cell biology research to mimic cAMP signaling and probe PKA-mediated pathways involved in regulation of proliferation, differentiation, and apoptosis. Supplied as a sodium salt powder with high purity suitable for in vitro assays.
- Cell-permeable cAMP analog for intracellular signaling studies.
- Activates cyclic AMP-dependent protein kinase (PKA).
- High purity suitable for biochemical and cellular assays.
- Stable sodium salt form for convenient handling and solution preparation.
- Available in small quantities for lab-scale experiments (e.g., 25 mg).
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Medchemexpress LLC Melamine | 108-78-1 | MFCD00006055 | 100.0% | 126.12 g/mol | C3H6N6 | 100g
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Melamine is an orally active inducer of Apoptosis Melamine induces animal disease models Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function Melamine also has neurotoxicity and nephrotoxicity Melamine induces cognitive impairment and acute kidney injury models Melamine can also be used to induce bladder cancer and urinary stone models[1][2][3][4][5][6]
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Medchemexpress LLC CYCLOHEXYLDIPHENYLPH 500G | 500G
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CYCLOHEXYLDIPHENYLPH 500G | 500G
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Medchemexpress LLC E/Envelope Dengue v 50ug
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E/Envelope Protein Dengue virus 2 (102a a P pastoris His) is the recombinant Virus-derived E/Envelope protein expressed by P pastoris with C-His labeled tag
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Apexbio Technology LLC (±)-Acetylcarnitine chloride 2504-11-2 100mg
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( )-Acetylcarnitine chloride (CAS 2504-11-2) is a cholinergic agonist and a metabolic intermediate involved in lipid metabolism It interacts with acetylcholine receptors including nicotinic and muscarinic subtypes and demonstrates the ability to modulate neurotransmitter systems In retinal ganglion cells both acetylcarnitine and acetylcholine suppress GABAergic responses indicating an influence on inhibitory synaptic transmission In animal models acetylcarnitine derivatives reduce ventricular arrhythmia following coronary artery ligation and enhance mitochondrial function Additionally acetyl-L-carnitine exhibits antinociceptive effects dependent on activation of the phospholipase C-IP3 signaling pathway This compound is frequently utilized in studies of neuromodulation cardiac function and pain signaling mechanisms
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Apexbio Technology LLC Piperacillin Sodium 59703-84-3 10mM (in 1mL DMSO)
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Piperacillin Sodium (CAS 59703-84-3) is a small-molecule inhibitor targeting bacterial penicillin-binding proteins (PBPs) It is designed to inhibit cell wall biosynthesis thereby disrupting peptidoglycan cross-linking in bacteria Piperacillin Sodium exerts its biological activity primarily through irreversible binding to bacterial transpeptidases (PBPs) In in vitro studies Piperacillin Sodium demonstrates antibacterial inhibition with IC50 values typically ranging from 2 to 16 g/ml depending on microorganism sensitivity and experimental conditions Based on these pharmacological properties Piperacillin Sodium holds research potential in microbiological studies and the investigation of Pseudomonas aeruginosa infections
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Apexbio Technology LLC Rabeprazole sodium 117976-90-6 10mM (in 1mL DMSO)
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Rabeprazole sodium (CAS 117976-90-6) is a small-molecule inhibitor targeting gastric H /K -ATPase It is designed to irreversibly inhibit this proton pump enzyme thereby suppressing gastric acid secretion Rabeprazole sodium exerts its biological activity primarily through irreversible inhibition of H /K -ATPase It also induces apoptosis and inhibits uridine nucleoside hydrolase (UNH) with an IC50 value of 0 3 M Based on these pharmacological properties Rabeprazole sodium holds research potential in studies of gastric ulcer gastroesophageal reflux disease and the investigation of proton pump inhibition apoptosis induction and nucleoside metabolism regulation
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Medchemexpress LLC N-lauryldiethanolamine | 1541-67-9 | MFCD00059002 | >95.0% | 273.45 g/mol | C16H35NO2 | 100 G
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N-Lauryldiethanolamine is an aliphatic tertiary amine used as an antistatic agent and surfactant. Supplier listings report bioactivity including inhibitory effects on cell growth and lysosomotropic behavior; consult safety data sheets for handling and toxicity information.
- Antistatic agent and surfactant
- Aminodiol structure; molecular formula C16H35NO2
- Molecular weight 273.45 g/mol
- CAS number 1541-67-9
- Typically supplied in 100 G packages
- Common purity: >95.0% (GC)
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Medchemexpress LLC Bromo-PEG1-C2-azide | 1144106-65-9 | 99.5% | C4H8BrN3O | 100 MG
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Bromo-PEG1-C2-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Click chemistry reagent with Azide group
- Reacts with Alkyne groups via CuAAc
- Reacts with DBCO or BCN groups via SPAAC
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Medchemexpress LLC Ponceau S, sodium salt | 6226-79-5 | MFCD00003892 | 75.0% | 760.57 g/mol | C22H12N4Na4O13S4 | 25G
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Ponceau S (sodium salt) is a water-soluble azo dye used for rapid, reversible staining of proteins on nitrocellulose, PVDF, and cellulose acetate membranes. Supplied as a powder for solution preparation, it is commonly used to visualize protein bands during membrane transfer checks and prior to immunodetection workflows, and can be removed without affecting downstream analyses.
- Provides rapid, reversible staining of protein bands on membranes.
- Compatible with nitrocellulose, PVDF, and cellulose acetate membranes.
- Water-soluble dye formulated for acidic staining solutions.
- Supplied as a powder for on-demand solution preparation and storage.
- Typical dye content 75% for routine visualization.
- Removes easily to permit subsequent immunodetection steps.
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Medchemexpress LLC Nicotinohydrazide | 553-53-7 | 99.35% | 137.14 | 100 G
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Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound used for research purposes. It exhibits cytotoxic activity and trypanosomicidal activity, making it suitable for various biological studies.
- Exhibits cytotoxic activity against human HeLa cells (CC50 of 153 μg/mL after 24 hours incubation).
- Shows trypanosomicidal activity against the amastigote stage of Trypanosoma cruzi Tulahuen C4 in Vero cells (IC50 > 73 μM after 5 days of incubation).
- Can be stored as powder at -20°C for 3 years or 4°C for 2 years.
- Can be stored in solvent at -80°C for 2 years or -20°C for 1 year.
- Soluble in DMSO (100 mg/mL).
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Medchemexpress LLC 2-BROMO-2 -METHOXYAC 10G | 10G
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2-BROMO-2 -METHOXYAC 10G | 10G
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Medchemexpress LLC Methylisothiazolinone hydrochloride | 26172-54-3 | 99.4% | 151.61 | 25 G
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Methylisothiazolinone hydrochloride is a bacterial and fungal inhibitor and preservative, also acting as a sensitizer. It activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells, leading to apoptosis and inflammatory responses. This compound can also promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses and cause mitochondrial damage in the endothelium of rat cerebral blood vessels.
- Acts as a bacterial and fungal inhibitor and preservative
- Induces cell apoptosis and inflammatory response
- Activates matrix metalloproteinases (MMPs)
- Promotes atopic dermatitis development in mice
- Causes mitochondrial damage in endothelium of rat cerebral blood vessels
- Decreases cell viability in bronchial epithelial cells
- Increases susceptibility of rat cerebral vascular endothelium to pathological stimuli
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Medchemexpress LLC GM-CSF Feline M36I 10ug | 10ug
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The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages including granulocytes macrophages eosinophils and erythrocytes Structurally GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex GM-CSF Protein Feline (M36I T56A K126N) is the recombinant GM-CSF protein expressed by E coli with tag free
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Medchemexpress LLC NIMA-related kinase 2 (NEK2) protein, human | >80.0% | 50UG
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Recombinant active human NEK2 kinase fragment (residues M1-I271) expressed in E. coli and supplied as a filtered solution formulated for stability. Intended for biochemical kinase assays, inhibitor screening, and research applications that require active NEK2 enzymatic activity.
- Active human NEK2 fragment (M1-I271).
- Produced in E. coli for recombinant expression.
- Approximate molecular weight 32.3 kDa.
- Supplied as a 0.22 μm filtered solution in 50 mM HEPES, pH 7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.
- Purity >80% by reducing SDS-PAGE.
- Tag free to avoid interference in assays.
- Available in small unit sizes suitable for assay development.
- Store at -80°C and avoid repeated freeze-thaw cycles.
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