Halophenols
Apexbio Technology LLC ZM 39923 HCl 1021868-92-7 10mM (in 1mL DMSO)
ZM 39923 HCl (CAS 1021868-92-7) is a small molecule that selectively inhibits Janus kinases JAK1 and JAK3 displaying pIC50 values of 4 4 and 7 1 respectively As JAK family kinases play a pivotal role in cytokine-mediated signaling via the JAK-STAT pathway ZM 39923 HCl is frequently employed to investigate signal transduction mechanisms linked to hematological malignancies autoimmune conditions and inflammatory disorders The compound also inhibits tissue transglutaminase 2 (TGM2) with an IC50 of 10 nM and exhibits equivalent inhibition of EGFR In cellular studies ZM 39923 HCl modulates T cell proliferation and apoptosis and affects pathways involving VEGF and TGF 2 underscoring its utility in cytokine oncology and cell biology research
Medchemexpress LLC 5-nitro-2-furaldehyde diacetate | 92-55-7 | MFCD00003244 | 1kg
IITR01324 is an antimicrobial agent IITR01324 has antimicrobial activity against Escherichia coli (MIC 3 58 mg/L) and other Gram-negative bacteria (Shigella flexneri MIC 3 58 mg/L Cronobacter sakazakii MIC 28 63 mg/L) IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases IITR01324 can be used to study the development of new antimicrobial drugs especially against multidrug-resistant (MDR) pathogens[1]
Medchemexpress LLC 5-nitro-2-furaldehyde diacetate | 92-55-7 | MFCD00003244 | 100g
IITR01324 is an antimicrobial agent IITR01324 has antimicrobial activity against Escherichia coli (MIC 3 58 mg/L) and other Gram-negative bacteria (Shigella flexneri MIC 3 58 mg/L Cronobacter sakazakii MIC 28 63 mg/L) IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases IITR01324 can be used to study the development of new antimicrobial drugs especially against multidrug-resistant (MDR) pathogens[1]
Medchemexpress LLC Methanediol, 1-(5-nitro-2-furanyl)-, 1,1-diacetate | 92-55-7 | MFCD00003244 | >98.0% | 500g
IITR01324 is an antimicrobial agent IITR01324 has antimicrobial activity against Escherichia coli (MIC 3 58 mg/L) and other Gram-negative bacteria (Shigella flexneri MIC 3 58 mg/L Cronobacter sakazakii MIC 28 63 mg/L) IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases IITR01324 can be used to study the development of new antimicrobial drugs especially against multidrug-resistant (MDR) pathogens[1]
Apexbio Technology LLC NPS-1034 1221713-92-3 5mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 10mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 25mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 50mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 100mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting