Halophenols
Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 5g
Chlorprothixene hydrochloride (CAS 6469-93-8) is a small-molecule antagonist targeting dopamine (D1 D2 D3 D5) and histamine H1 receptors It modulates neurotransmission by blocking these receptors thereby regulating dopaminergic and histaminergic pathways Chlorprothixene hydrochloride exerts its biological activity primarily through receptor antagonism In in vitro studies it demonstrates nanomolar affinity with Ki values of 18 nM (D1) 2 96 nM (D2) 4 56 nM (D3) 9 nM (D5) and 3 75 nM (H1) Additionally it reduces SARS-CoV viral replication (IC50 13 0 18 5 M depending on strain) Based on these pharmacological properties chlorprothixene hydrochloride holds research potential in antipsychotic therapy antiviral investigation and modulation of inflammation in cystic fibrosis models
Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 25g
Chlorprothixene hydrochloride (CAS 6469-93-8) is a small-molecule antagonist targeting dopamine (D1 D2 D3 D5) and histamine H1 receptors It modulates neurotransmission by blocking these receptors thereby regulating dopaminergic and histaminergic pathways Chlorprothixene hydrochloride exerts its biological activity primarily through receptor antagonism In in vitro studies it demonstrates nanomolar affinity with Ki values of 18 nM (D1) 2 96 nM (D2) 4 56 nM (D3) 9 nM (D5) and 3 75 nM (H1) Additionally it reduces SARS-CoV viral replication (IC50 13 0 18 5 M depending on strain) Based on these pharmacological properties chlorprothixene hydrochloride holds research potential in antipsychotic therapy antiviral investigation and modulation of inflammation in cystic fibrosis models
Medchemexpress LLC Chlorprothixene hydrochloride | 6469-93-8 | 99.91% | 1 ML
Chlorprothixene hydrochloride is an antagonist of dopamine and histamine receptors, exhibiting antipsychotic activity. It demonstrates specific Ki values for hD1, hD2, hD3, hD5, and hH1 receptors, and binds to 5-HT receptors with distinct pKis.
- Antagonist of dopamine and histamine receptors
- Exhibits antipsychotic activity
- Binds to 5-HT receptors
- Purity of 99.91%
Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 10mM (in 1mL DMSO)
Chlorprothixene hydrochloride (CAS 6469-93-8) is a small-molecule antagonist targeting dopamine (D1 D2 D3 D5) and histamine H1 receptors It modulates neurotransmission by blocking these receptors thereby regulating dopaminergic and histaminergic pathways Chlorprothixene hydrochloride exerts its biological activity primarily through receptor antagonism In in vitro studies it demonstrates nanomolar affinity with Ki values of 18 nM (D1) 2 96 nM (D2) 4 56 nM (D3) 9 nM (D5) and 3 75 nM (H1) Additionally it reduces SARS-CoV viral replication (IC50 13 0 18 5 M depending on strain) Based on these pharmacological properties chlorprothixene hydrochloride holds research potential in antipsychotic therapy antiviral investigation and modulation of inflammation in cystic fibrosis models
Medchemexpress LLC N-Fmoc-8-aminooctanoic acid | 126631-93-4 | 98.95% | 381.46 | 25 G
N-Fmoc-8-aminooctanoic acid is a PROTAC linker used in the synthesis of PROTACs. It is an alkane chain featuring terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic conditions to yield a free amine, which is suitable for further conjugations. The terminal carboxylic acid can form a stable amide bond by reacting with primary amine groups in the presence of activators like EDC or HATU. This product is for research use only.
- Can be used as a PROTAC linker.
- Contains an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups.
- Fmoc group can be deprotected for further conjugations.
- Terminal carboxylic acid can form stable amide bonds with primary amine groups.
Medchemexpress LLC N-Fmoc-8-aminooctanoic acid | 126631-93-4 | 99.0% | 381.46 | 5 G
N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. It is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic conditions to obtain a free amine for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g., EDC or HATU) to form a stable amide bond.
- Can be used as a PROTAC linker
- Alkane chain with terminal Fmoc-protected amine and carboxylic acid groups
- Fmoc group can be deprotected under basic conditions
- Terminal carboxylic acid can react with primary amine groups to form a stable amide bond
Medchemexpress LLC 4-Amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboxamide | 942436-93-3 | 99.1% | 366.41 | 25 MG
AZD-6280 is a selective GABAA(α2/3) receptor modulator, used for the treatment of generalized anxiety disorder.
- Selective GABAA(α2/3) receptor modulator
- Used for the treatment of generalized anxiety disorder