Nitrophenols
Sigma Aldrich methyldodecylbenzyl trimethyl ammonium chloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 3,5-Dinitrosalicylic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC FHD-609 | 2676211-64-4 | C47H56N8O6 | 250 MG
FHD-609 is a PROTAC degrader and inhibitor of BRD9 (Bromodomain-containing protein 9). It targets ncBAF and is used for research in various cancers with mutations in a BAF complex subunit. It may also play a role in adrenocortical carcinoma (ACC) treatment when combined with Telomelysin or INO5401.
- Targets BRD9 (Bromodomain-containing protein 9)
- Functions as a PROTAC degrader and inhibitor
- Useful for research on various cancers with BAF complex subunit mutations
- Shows anti-tumor activities in vivo
- High purity of 98.95%
- Appearance is solid, white to off-white
Apexbio Technology LLC STO-609 acetate 1173022-21-3 5mg
STO-609 acetate (CAS 1173022-21-3) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase kinase (CaM-KK) demonstrating Ki values of 80 ng/ml for CaM-KK and 15 ng/ml for CaM-KK This compound exhibits marked specificity for CaM-KK isoforms with minimal activity against downstream CaM kinases such as CaM-KI and CaM-KIV and an IC50 of approximately 10 g/ml for CaM-KII In cell-based studies STO-609 suppresses Ca2 -induced activation of CaM-KIV and reduces endogenous CaM-KK activity In vivo STO-609 administration enhances osteoblast formation and inhibits osteoclast differentiation in mouse models highlighting its utility in studies of calcium signaling and bone metabolism
Medchemexpress LLC Fhd-609 | 2676211-64-4 | 99.2% | 829.00 | C47H56N8O6 | 10 MG
FHD-609 is a selective heterobifunctional degrader (PROTAC) of bromodomain-containing protein 9 (BRD9). It induces targeted proteasomal degradation via CRBN recruitment and is used in research to study BRD9 biology, ncBAF complex function, and oncology-related applications. The compound is supplied as a high-purity material for laboratory use and formulation work.
- Selective BRD9 degrader and inhibitor.
- High purity (>99%) suitable for research use.
- Applicable to in vitro and preclinical studies.
- Facilitates study of ncBAF complex and BRD9-related cancers.
- Molecular weight 829.00 and formula C47H56N8O6.
Medchemexpress LLC FHD-609 | 2676211-64-4 | C47H56N8O6 | 500 MG
FHD-609 is a PROTAC degrader and inhibitor of BRD9 (Bromodomain-containing protein 9), targeting ncBAF. It can be utilized for research into various cancers featuring mutations in a BAF complex subunit. This compound has demonstrated sustained BRD9 degradation and anti-tumor activities in preclinical models. In combination with Telomelysin or INO5401, FHD-609 may contribute to the treatment of adrenocortical carcinoma (ACC).
- Targets ncBAF
- Used for research into cancers with BAF complex subunit mutations
- Exhibits anti-tumor activities in preclinical models
- May be useful in adrenocortical carcinoma (ACC) treatment when combined with other agents
Pfaltz & Bauer p-Nitrophenol sodium salt Tech 100G | 824-78-2
p-Nitrophenol sodium salt Tech 100G | 824-78-2
TARGETMOL CHEMICALS INC STO-609 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKalpha/KKbeta (Ki 80/15 ng/mL). Purity 98.95%
Medchemexpress LLC FHD-609 | 2676211-64-4 | C47H56N8O6 | 1 G
FHD-609 is a PROTAC degrader and inhibitor of BRD9 (Bromodomain-containing protein 9). It targets ncBAF and can be used for research on a wide range of cancers that contain a mutation in a BAF complex subunit. When combined with Telomelysin or INO5401, FHD-609 may have a role in adrenocortical carcinoma (ACC) treatment.
- PROTAC degrader and inhibitor of BRD9 (Bromodomain-containing protein 9).
- Targets ncBAF.
- Applicable for research into cancers with a mutation in a BAF complex subunit.
- Potential for adrenocortical carcinoma (ACC) treatment in combination with Telomelysin or INO5401.
- Purity: 98.95%.
- Molecular weight: 829.00.
- Formula: C47H56N8O6.
- Appearance: Solid, white to off-white.
Medchemexpress LLC STO-609 | 52029-86-4 | 98.2% | 314.29 | 1 ML
STO-609 is a selective and cell-permeable inhibitor of Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), exhibiting Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. It inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates (IC50 ~0.02 g/ml) and is highly selective for CaM-KK, with no significant effect on downstream CaM-KI and -IV. It also inhibits both constitutively active and wild-type CaM-KKα, and suppresses Ca2+-induced activation of CaM-KIV. The inhibition mechanism is ATP-competitive.
- Selective and cell-permeable CaM-KK inhibitor.
- Inhibits AMPKK activity.
- High selectivity for CaM-KK.
- Suppresses Ca2+-induced activation of CaM-KIV.
- ATP-competitive inhibition mechanism.
Medchemexpress LLC 3,5-Dinitrosalicylic acid | 609-99-4 | 100.0% | 228.12 | 100 G
3,5-Dinitrosalicylic acid is a derivative of salicylic acid and is used in the α-amylase assay, carbohydrase assay, and for the colorimetric determination of reducing substances. It is a commonly used reducing sugar detection reagent that undergoes an oxidation-reduction reaction with reducing sugars to generate derivatives, producing a color change for quantitative detection of reducing sugar content.
- Used in α-amylase assay.
- Used in carbohydrase assay.
- Used for colorimetric determination of reducing substances.
- Commonly used reducing sugar detection reagent.
- Undergoes oxidation-reduction reaction with reducing sugars.
- Enables quantitative detection of reducing sugar content via color change.
Medchemexpress LLC FHD-609 | 2676211-64-4 | C47H56N8O6 | 25 MG
FHD-609 is a PROTAC degrader and inhibitor of BRD9 (Bromodomain-containing protein 9). It targets ncBAF and is intended for research related to various cancers that possess a mutation in a BAF complex subunit. This compound, when combined with Telomelysin or INO5401, may be instrumental in the treatment of adrenocortical carcinoma (ACC).
- PROTAC degrader and inhibitor of BRD9
- Targets ncBAF
- Used for research on cancers with BAF complex subunit mutations
- May play a role in adrenocortical carcinoma (ACC) treatment in combination with Telomelysin or INO5401
- Demonstrated sustained BRD9 degradation and anti-tumor activities in SYO-1 xenograft mouse models
- Involved in a Phase 1 clinical trial for advanced synovial sarcoma
- Purity is 98.95%
- Appears as a white to off-white solid
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC FHD-609 | 2676211-64-4 | C47H56N8O6 | 100 MG
FHD-609 is a PROTAC degrader and inhibitor of Bromodomain-containing protein 9 (BRD9). It targets ncBAF and is used for research on various cancers with mutations in a BAF complex subunit. This compound, when combined with Telomelysin or INO5401, may be useful in adrenocortical carcinoma (ACC) treatment.
- Purity: 98.95%
- Appearance: Solid, white to off-white
- Target: BRD9, epigenetic reader domain, PROTACs
- Demonstrates maintained BRD9 degradation levels and anti-tumor activities in SYO-1 xenograft mouse models
- In vitro solubility: Soluble in DMSO at 100 mg/mL (120.63 mM), requires ultrasonication
- In vivo solubility: Forms clear solutions in 10% DMSO with 90% (20% SBE-β-CD in saline) or 90% corn oil at ≥ 2.5 mg/mL (3.02 mM)
Sigma Aldrich Fine Chemicals Biosciences 3 5-DINITROSALICYLIC ACID
NC2754830 3 5-DINITROSALICYLIC ACID