Nitrophenols
Medchemexpress LLC FHD-609 | 2676211-64-4 | C47H56N8O6 | 100 MG
FHD-609 is a PROTAC degrader and inhibitor of Bromodomain-containing protein 9 (BRD9). It targets ncBAF and is used for research on various cancers with mutations in a BAF complex subunit. This compound, when combined with Telomelysin or INO5401, may be useful in adrenocortical carcinoma (ACC) treatment.
- Purity: 98.95%
- Appearance: Solid, white to off-white
- Target: BRD9, epigenetic reader domain, PROTACs
- Demonstrates maintained BRD9 degradation levels and anti-tumor activities in SYO-1 xenograft mouse models
- In vitro solubility: Soluble in DMSO at 100 mg/mL (120.63 mM), requires ultrasonication
- In vivo solubility: Forms clear solutions in 10% DMSO with 90% (20% SBE-β-CD in saline) or 90% corn oil at ≥ 2.5 mg/mL (3.02 mM)
Chem-Impex International, Inc. 3,5-Dinitrosalicylic acid | 609-99-4 | MFCD00007104 | 100G
3,5-Dinitrosalicylic acid, 609-99-4, MFCD00007104, 100G
Medchemexpress LLC STO-609 | 52029-86-4 | 98.2% | 314.29 | 1 ML
STO-609 is a selective and cell-permeable inhibitor of Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), exhibiting Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. It inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates (IC50 ~0.02 g/ml) and is highly selective for CaM-KK, with no significant effect on downstream CaM-KI and -IV. It also inhibits both constitutively active and wild-type CaM-KKα, and suppresses Ca2+-induced activation of CaM-KIV. The inhibition mechanism is ATP-competitive.
- Selective and cell-permeable CaM-KK inhibitor.
- Inhibits AMPKK activity.
- High selectivity for CaM-KK.
- Suppresses Ca2+-induced activation of CaM-KIV.
- ATP-competitive inhibition mechanism.
Chem-Impex International, Inc. 3,5-Dinitrosalicylic acid | 609-99-4 | MFCD00007104 | 250G
3,5-Dinitrosalicylic acid, 609-99-4, MFCD00007104, 250G
Sigma Aldrich Fine Chemicals Biosciences 3 5-DINITROSALICYLIC ACID
NC2754830 3 5-DINITROSALICYLIC ACID
![Medchemexpress LLC 7-oxo-7H-benzimidazo[2,1-a]benzo[de]isoquinoline-3-carboxylic acid | 52029-86-4 | MFCD30685721 | 98.2% | 314.29 | C19H10N2O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000297549.png-250.jpg)
Medchemexpress LLC 7-oxo-7H-benzimidazo[2,1-a]benzo[de]isoquinoline-3-carboxylic acid | 52029-86-4 | MFCD30685721 | 98.2% | 314.29 | C19H10N2O3 | 10 MG
STO-609 is a selective, cell-permeable inhibitor of calmodulin-dependent protein kinase kinase (CaMKK) used as a research tool to probe CaMKK/CaMK and AMPK signaling pathways in biochemical and cell-based studies. The compound is supplied as a solid research reagent with documented purity, solubility, and storage recommendations for laboratory use.
- Selective inhibitor of CaMKK with activity against CaMKKα and CaMKKβ.
- Cell-permeable small molecule suitable for cellular assays.
- Useful probe for AMPK and autophagy pathway studies.
- Purity 98.2% by HPLC.
- Molecular weight 314.29; formula C19H10N2O3; CAS 52029-86-4.
- Available in small research sizes, including 10 mg.
- Solubility varies by vehicle; soluble in DMSO and PEG-containing formulations.
- Store sealed at 4°C; in solvent, store at -80°C for long-term stability.
Medchemexpress LLC Fhd-609 | 2676211-64-4 | 99.2% | 829.00 | C47H56N8O6 | 10 MG
FHD-609 is a selective heterobifunctional degrader (PROTAC) of bromodomain-containing protein 9 (BRD9). It induces targeted proteasomal degradation via CRBN recruitment and is used in research to study BRD9 biology, ncBAF complex function, and oncology-related applications. The compound is supplied as a high-purity material for laboratory use and formulation work.
- Selective BRD9 degrader and inhibitor.
- High purity (>99%) suitable for research use.
- Applicable to in vitro and preclinical studies.
- Facilitates study of ncBAF complex and BRD9-related cancers.
- Molecular weight 829.00 and formula C47H56N8O6.
Medchemexpress LLC 3,5-Dinitrosalicylic acid | 609-99-4 | 100.0% | 228.12 | 25 G
3,5-Dinitrosalicylic acid is a derivative of salicylic acid. It is utilized in α-amylase assays, carbohydrase assays, and for the colorimetric determination of reducing substances. This product functions as a commonly used reducing sugar detection reagent, undergoing an oxidation-reduction reaction with reducing sugars to generate derivatives, which results in a color change for quantitative detection of reducing sugar content.
- Derivative of salicylic acid.
- Utilized in α-amylase assays.
- Utilized in carbohydrase assays.
- Used for the colorimetric determination of reducing substances.
- Functions as a commonly used reducing sugar detection reagent.
- Undergoes an oxidation-reduction reaction with reducing sugars to generate derivatives.
- Results in a color change for quantitative detection of reducing sugar content.
eMolecules 2-Methyl-6-nitrophenol | 13073-29-5 | MFCD00031116 | 1g
Combi-Blocks | 2-Methyl-6-nitrophenol | 1g | 205380804 | AN-2925 | 98.000 | 13073-29-5 | MFCD00031116 | 153.137 | C7H7NO3
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eMolecules 2-Nitrophenol sodium salt | 824-39-5 | MFCD00065178 | 5g
Combi-Blocks | 2-Nitrophenol sodium salt | 5g | 205396993 | QA-1640 | 98.000 | 824-39-5 | MFCD00065178 | 161.092 | C6H4NNaO3
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Selleck Chemical LLC STO-609
STO-609 is a specific inhibitor of the Ca2 /Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KK and CaM-KK isoforms with Ki values of 80 and 15 ng/ml respectively and also inhibits their autophosphorylation activities STO-609 inhibits AMPKK activity and inhibits autophagy
Apexbio Technology LLC STO-609 acetate 1173022-21-3 10mg
STO-609 acetate (CAS 1173022-21-3) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase kinase (CaM-KK) demonstrating Ki values of 80 ng/ml for CaM-KK and 15 ng/ml for CaM-KK This compound exhibits marked specificity for CaM-KK isoforms with minimal activity against downstream CaM kinases such as CaM-KI and CaM-KIV and an IC50 of approximately 10 g/ml for CaM-KII In cell-based studies STO-609 suppresses Ca2 -induced activation of CaM-KIV and reduces endogenous CaM-KK activity In vivo STO-609 administration enhances osteoblast formation and inhibits osteoclast differentiation in mouse models highlighting its utility in studies of calcium signaling and bone metabolism