Carboxylic acid salts
Medchemexpress LLC Tasurgratinib succinate | 1879965-80-6 | 99.2% | 764.82 g/mol | C32H37N5O6·3/2 C4H6O4 | 25 MG
Tasurgratinib succinate is an orally available, selective small-molecule inhibitor of fibroblast growth factor receptors FGFR1, FGFR2, and FGFR3. Supplied as the succinate salt for research use, the compound is characterized by a defined molecular formula and high purity for preclinical and translational studies probing FGFR-driven signaling and anticancer activity.
- Selective FGFR1-3 inhibition with low nanomolar potency.
- High reported purity suitable for research applications.
- Supplied as a succinate salt for improved stability and handling.
- Molecular weight and formula provided for analytical characterization.
- Soluble in common organic solvents for in vitro testing.
AdipoGen Ganglioside GD1b 2Na bovine
Chemical. CAS 19553-76-5. Formula C84H146N4O39 . 2Na. MW 1836.1 . 46.0 calculated on sphingosine C181 and stearic acid. Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1b may act as a bacterial toxin receptor tetanus, botulinus. High levels are found in gliomas and astrocytomas. It modulates protein kinase activities. In vivo and in vitro it is in equilibrium with the lactone structure.
Apexbio Technology LLC Nigericin sodium salt 28643-80-3 50 mg
Nigericin sodium salt is a lipid-soluble ionophore functioning by facilitating K /H exchange across biological membranes Experimentally it modulates intracellular pH levels through its ion-transport activity influencing cellular processes sensitive to pH homeostasis such as platelet aggregation and energy metabolism pathways Nigericin exhibits limited inhibitory effects on platelet aggregation induced by agonists like thrombin or ADP correlating primarily with reductions in cytoplasmic pH Additionally nigericin has demonstrated capacity to transport Pb2 ions across membranes selectively suggesting potential utility in experimental models targeting metal ion homeostasis and heavy-metal toxicity research Nigericin exhibits inhibitory activity on ATP-driven transhydrogenase reactions showing varied IC50 depending upon ATP concentrations and experimental conditions (IC50 values typically range from low micromolar to submillimolar concentrations)
Sigma Aldrich Fine Chemicals Biosciences Alginic acid sodium salt f500G
Alginic acid sodium salt f500G
Apexbio Technology LLC Rigosertib sodium salt 1225497-78-8 10mM (in 1mL DMSO)
Rigosertib sodium salt (CAS 1225497-78-8) is a selective inhibitor targeting Polo-like kinase 1 (PLK1) with reported IC50 approximately 9 nM The compound notably decreases proliferation of cancer cell lines demonstrating nanomolar IC50 values in HeLa (115 nM) and C33A (45 nM) cells whereas normal cells (e g BJ and Ect1/E6E7) remain largely unaffected At concentrations exceeding 0 5 M rigosertib robustly induces G2/M phase arrest in cancer cells without significant cell cycle disruption at lower doses Additionally in vivo studies suggest its potential as a radiosensitizer in cervical carcinoma research
Apexbio Technology LLC Cefoperazone (sodium salt) 62893-20-3 10g
Cefoperazone sodium salt (CAS 62893-20-3) is a semi-synthetic cephalosporin antibiotic targeting penicillin-binding proteins It is designed to inhibit bacterial cell wall synthesis thereby compromising cell wall stability and inducing bacterial cell lysis Cefoperazone sodium salt exerts its biological activity primarily through inhibition of bacterial cell wall synthesis In in vitro studies cefoperazone sodium salt demonstrates broad-spectrum antibacterial activity with MIC50 values ranging from 0 004 0 06 g/ml against Neisseria gonorrhoeae isolates Based on these pharmacological properties cefoperazone sodium salt holds research potential in experimental infection models to investigate bacterial susceptibility resistance mechanisms and pharmacokinetic properties in clinical microbiology and infectious diseases
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 10mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
eMolecules Amino-Gly-Gly-DSPE HCl salt | | | 250mg
Broadpharm | Amino-Gly-Gly-DSPE HCl salt | 250mg | 528284389 | BP-24528 | 95.000 | | | 898.640 | C45H89ClN3O10P
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Avanti Polar Lipids CARBOXYLIC ACID 50 MG
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt) | 1403744-37-5
Avanti Polar Lipids CARBOXYLIC ACID 100 MG
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt) | 1403744-37-5
TARGETMOL CHEMICALS INC FOSBRETABULIN DISODIUM 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Fosbretabulin Disodium (CA 4P) a water-soluble prodrug of Combretastatin A4 (CA4) is a microtubule-targeting agent that binds (beta)-tubulin (Kd 0.4 uM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50 2.4 uM) and also disrupts tumor vasculature. purity: 99%
TARGETMOL CHEMICALS INC LY-2584702 TOSYLATE SALT 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. LY-2584702 tosylate salt is a selective ATP-competitive p70S6K inhibitor used in trials studying the treatment of cancer. purity: 98%
eMolecules 2-Amino-5-sulfobenzoic acid | 3577-63-7 | MFCD00035763 | 1g
Combi-Blocks | 2-Amino-5-sulfobenzoic acid | 1g | 267202219 | QG-4186 | 95.000 | 3577-63-7 | MFCD00035763 | 217.200 | C7H7NO5S
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