Carboxylic acid salts
Apexbio Technology LLC Methicillin (sodium salt) 132-92-3 100mg
Methicillin sodium salt is a semisynthetic antibiotic belonging to the penicillin class characterized by inhibition of bacterial cell wall synthesis It exerts bactericidal activity by binding covalently to bacterial transpeptidases (penicillin-binding proteins PBPs) disrupting peptidoglycan cross-link formation and compromising cell wall integrity Methicillin has been employed in research primarily against gram-positive bacteria including penicillinase-producing strains such as Staphylococcus aureus Experimentally methicillin can serve as a reference compound in vitro studies evaluating antimicrobial susceptibility or resistance mechanisms The minimum inhibitory concentration (MIC) values reported typically range between 0 5 to 4 g/mL depending upon bacterial strain and experimental conditions Currently its primary use is confined to laboratory research due to availability of alternative penicillin derivatives
AdipoGen D-Luciferin potassium salt
Chemical. CAS 115144-35-9. Formula C11H7KN2O3S2. MW 318.41. D-Luciferin is the most popular and versatile bioluminescent substrate. Firefly luciferase produces light by the ATP-dependent oxidation Mg2 as cofactor of luciferin. It emits a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo. The 560nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase activity when luciferin and ATP are present in excess. Firefly luciferase has long been conjugated to antibodies and used as a label in immunoassays using luciferin as the substrate for detection. One particular advantage to the enzyme is that there is low endogenous luciferase activity in mammalian tissues besides its high sensitivity. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.
Cayman Chemical NADP sodium salt hydrate
The oxidized form of NADPH; serves as a cofactor in various biological reactions
Apexbio Technology LLC Cefazolin (sodium salt) 27164-46-1 1g
Cefazolin sodium salt (CAS 27164-46-1) is a semisynthetic antibiotic that inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins thereby blocking transpeptidation reactions essential for peptidoglycan formation In in vitro studies cefazolin sodium salt suppresses the proliferation of cultured osteoblast-like MG-63 cells exhibiting substantial cytotoxicity at concentrations of 10 000 g/ml precise IC50 values depend on cell type and experimental conditions Cefazolin sodium salt is commonly used in microbiology pharmacokinetic investigations and infection models particularly within studies of antimicrobial susceptibility and renal dysfunction
TARGETMOL CHEMICALS INC NIGERICIN SODIUM SALT 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.Nigericin sodium is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It also prevents viral activation and triggers activation of the NALP3 inflammasome. purity: 99%
TARGETMOL CHEMICALS INC FOSTAMATINIB DISODIUM 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. purity: 98%
Cayman Chemical FR900098 sodium salt
A derivative of fosmidomycin that has antimalarial activity; inhibits DOXP reductoisomerase in vitro in a dose-dependent manner; exhibits in vitro antimalarial activity against three P. falciparum strains (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 strains, respectively); FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice
Cayman Chemical Fluvastatin sodium salt hydr
An HMG-CoA reductase inhibitor (Ki = 0.3 nM for the rat enzyme); inhibits CYP2C9 (IC50 = 100 nM); inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in GPX4 and system Xc- levels in HUVECs; decreases serum cholesterol, triglyceride, and phospholipid levels, the formation of TBARS, and vascular ACE activity in rabbits fed a high-cholesterol diet at 2 mg/kg per day; increases survival in a mouse model of myocardial infarction at 10 mg/kg per day
Sigma Aldrich Fine Chemicals Biosciences Suramin sodium salt 98 TLC25MG
Suramin is an antiparasitic drug which blocks endothelial cell proliferation and increases tyrosine phosphorylation of many signalling proteins. It is associated with urticaria paresthesias vomitingnbspand neurologic toxicity. Suramin is used to treat trypanosomiasis and onchocerciasis. It functions as an inhibitor of heparanasenbspand also exhibits anti-AIDS (acquired immunodeficiency syndrome) property.
Apexbio Technology LLC Concanavalin A (Con A)-FITC 5x5mg(5 mg/mL)
Concanavalin A (Con A) derived from Canavalia ensiformis (jack bean) is a plant lectin protein with a molecular weight of approximately 104 kDa Each subunit can bind one Ca2 ion and one Mn2 ion and has one carbohydrate binding site Con A is capable of binding to various glycoproteins glycolipids and -D-glucose and -D-mannose residues FITC is a fluorescent dye that emits a green fluorescence under UV light (Ex/Em 495 nm/515 nm) This combination endows Con A-FITC with high visualization capability making it efficient for detecting carbohydrate molecules on the cell surface This product is FITC-labeled Con A in solution form It is applicable in glycobiology research serving as a probe to detect carbohydrate molecules on the cell surface and analyzed effectively using flow cytometry Applying IHC staining procedures with this product allows visualization of carbohydrate distribution in tissues or cells under a fluorescence microscope
Medchemexpress LLC Tasurgratinib succinate | 1879965-80-6 | 99.2% | 705.8 g/mol | C32H37N5O6.3/2C4H6O4 | 10 MG
Tasurgratinib succinate (E7090) is an orally available, selective inhibitor of fibroblast growth factor receptors FGFR1-3 used in preclinical oncology research. It potently inhibits FGFR signaling at low-nanomolar concentrations and has demonstrated antiproliferative activity in FGFR-driven cancer cell lines.
- Selective FGFR1-3 inhibition with low-nanomolar potency.
- Demonstrated antiproliferative activity in FGFR-driven cell lines.
- Supplied as the succinate salt for preclinical experiments.
- High purity suitable for biochemical and cellular assays.
- Provided in small-mass packages for research use.
Apexbio Technology LLC Concanavalin A (Con A) Solution (500X) 4x100uL
Concanavalin A (Con A) derived from Canavalia ensiformis (jack bean) is a plant lectin protein (Mw 104 kDa) Under pH 7 0 Con A exists as a homotetramer composed of four subunits of 26 kDa each Under pH 4 5-5 5 Con A dissociates into active dimers (52 kDa) Acetylation succinylation or other chemical modifications can also produce stable dimeric forms Each subunit is capable of binding one Ca2 and one Mn2 and contains a carbohydrate-binding site After binding metal ions Con A can specifically bind to glycoproteins glycolipids and carbohydrate moieties containing -D-glucose and -D-mannose It is used for carbohydrate analysis glycoprotein purification enzyme tagging cell membrane studies cell agglutination assays cell cultures and cell typing This product is a ready-to-use aqueous buffered solution (500X concentrate) of Con A and serves as an exogenous lectin suitable for use as a potent leukocyte mitogen
Cayman Chemical Pravastatin sodium salt
A potent HMG-CoA reductase inhibitor (Ki = 2.3 nM); reduces total plasma cholesterol levels by 29% in dogs at 20 mg/kg per day for five weeks
Medchemexpress LLC NADP sodium salt | 1184-16-3 | MFCD00150480 | 98.7% | 765.39 | C21H27N7NaO17P3 | 10 MG
NADP sodium salt is the sodium salt form of nicotinamide adenine dinucleotide phosphate supplied as an analytical standard for research and analytical applications. It participates in cellular redox reactions by cycling between oxidized (NADP+) and reduced (NADPH) states, and is used as a reference reagent in biochemical and analytical assays.
- Purity 98.7% (analytical)
- Molecular weight 765.39 g/mol
- Molecular formula C21H27N7NaO17P3
- Solid, white to off-white appearance
- Available in small research pack sizes, including 10 MG
- Intended for research and analytical applications; for research use only
AdipoGen Ganglioside GD1b 2Na bovine
Chemical. CAS 19553-76-5. Formula C84H146N4O39 . 2Na. MW 1836.1 . 46.0 calculated on sphingosine C181 and stearic acid. Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1b may act as a bacterial toxin receptor tetanus, botulinus. High levels are found in gliomas and astrocytomas. It modulates protein kinase activities. In vivo and in vitro it is in equilibrium with the lactone structure.