Carboxylic acid salts
Cayman Chemical MK886 sodium salt
A potent FLAP antagonist that prevents 5-LO activation in vivo; inhibits LT biosynthesis in leukocytes with an IC50 value of 2.5 nM
Sigma Aldrich Fine Chemicals Biosciences NADP Disodium salt
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential thereby influencing metabolic reactions in vivo.
Selleck Chemical LLC Nigericin sodium salt
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that works by acting as an H K and Pb2 ionophore Nigericin can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes
Apexbio Technology LLC GSK1349572 sodiuM salt 1051375-19-9 50mg
GSK1349572 sodium salt (CAS 1051375-19-9) is a small-molecule inhibitor targeting HIV integrase It is designed to inhibit the integrase-mediated strand transfer process thereby blocking the integration of viral DNA into the host genome GSK1349572 sodium salt exerts its biological activity primarily through interaction with the enzyme s two-metal ion catalytic site inhibiting strand transfer In in vitro studies GSK1349572 sodium salt demonstrates potent antiviral inhibition with a protein-adjusted IC50 of approximately 38 nM in the presence of 100% human serum Based on these pharmacological properties GSK1349572 sodium salt holds research potential in antiviral studies evaluation of resistance profiles and drug development of integrase inhibitors for HIV therapy
AdipoGen DL-3-Hydroxybutyric acid Na
Chemical. CAS 150-83-4. Formula C4H7NaO3. MW 126.1. Synthetic. Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.
TARGETMOL CHEMICALS INC POPG sodium salt 25MG
Also available in 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. POPG sodium salt is a phospholipid with a negative charge and is a component of biological membranes. It can be used to study the function of biological membranes.
TARGETMOL CHEMICALS INC NADP DISODIUM SALT 500MG
Also available in 100 mg 200 mg and bulk. Please contact Fisher for quotes. NADP disodium salt (Disodium NADP) is a nicotinamide adenine dinucleotide. NADP disodium salt is a key redox cofactor for electron transfer in the metabolism serves as an electron carrier in a number of reactions being alternately oxidized (NADP+) and reduced (NADPH). purity: 98%
TARGETMOL CHEMICALS INC CARBENOXOLONE DISODIUM 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers especially in the stomach. Antidiuretic side effects are frequent but otherwise the drug is low in toxicity. purity: 98%
Medchemexpress LLC Suramin sodium salt | 129-46-4 | 100.0% | 5 MG
Suramin sodium salt is a versatile compound acting as a reversible and competitive inhibitor of protein-tyrosine phosphatases (PTPases). It also inhibits sirtuins and reverse transcriptase. It has been identified as an antiparasitic, anti-neoplastic, and anti-angiogenic agent, and is also a potent inhibitor of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp).
- Reversible and competitive PTPases inhibitor
- Potent inhibitor of sirtuins (SirT1, SirT2, SirT5)
- Competitive inhibitor of reverse transcriptase (DNA topoisomerase II)
- Potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor
- Efficiently inhibits IP5K
- Acts as an antiparasitic, anti-neoplastic, and anti-angiogenic agent
Medchemexpress LLC E7766 diammonium salt | 2242635-03-4 | 99.5% | 780.66 | 10 MG
E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. It demonstrates potent pan-genotypic and antitumor activities. For research use only, not for sale to patients.
- Macrocycle-bridged STING agonist
- Kd of 40 nM
- Potent pan-genotypic activity
- Potent antitumor activities
- Inhibits four human STING variants (human wild-type, HAQ, AQ, and REF STING proteins) with EC50 values of 1 μM, 2.2 μM, 1.2 μM, and 4.9 μM, respectively
- Shows potent antitumor activity with long-lasting immune memory response in a mouse liver metastatic tumor model
Medchemexpress LLC L 012 sodium salt | 143556-24-5 | 99.9% | 310.67 | 10 MG
L 012 sodium salt is a luminal-based chemiluminescent probe that can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)).
- Luminal-based chemiluminescent probe.
- Detects NADPH oxidase (Nox)-derived superoxide and nitrogen species (ROS and RNS).
Medchemexpress LLC L 012 sodium salt | 143556-24-5 | 99.9% | 310.67 | 1 MG
L 012 sodium salt is a luminal-based chemiluminescent probe that can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)).
- Detects NADPH oxidase (Nox)-derived superoxide and nitrogen species.
- Identifies reactive oxygen species (ROS) and reactive nitrogen species (RNS).
- Suitable for research applications.
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 500mg
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics
Apexbio Technology LLC CL 316243 disodium salt 151126-84-0 10mg
CL 316243 disodium salt is a small-molecule agonist targeting the 3-adrenergic receptor It is designed to activate 3 receptors thereby modulating lipolytic and thermogenic pathways predominantly in adipose tissues CL 316243 disodium salt exerts its biological activity by selectively binding to 3-adrenergic receptors leading to enhanced adipocyte-mediated lipid metabolism In experimental rodent models administration of CL 316243 increases insulin sensitivity and reduces obesity-related hyperglycemia by promoting glucose uptake primarily in adipose tissue Based on these pharmacological properties CL 316243 disodium salt holds research potential in the study of 3 receptor-mediated metabolic mechanisms and the exploration of therapeutic strategies for metabolic disorders such as obesity and type 2 diabetes