Carboxylic acid salts
Apexbio Technology LLC Cefoperazone (sodium salt) 62893-20-3 5g
Cefoperazone sodium salt (CAS 62893-20-3) is a semi-synthetic cephalosporin antibiotic targeting penicillin-binding proteins It is designed to inhibit bacterial cell wall synthesis thereby compromising cell wall stability and inducing bacterial cell lysis Cefoperazone sodium salt exerts its biological activity primarily through inhibition of bacterial cell wall synthesis In in vitro studies cefoperazone sodium salt demonstrates broad-spectrum antibacterial activity with MIC50 values ranging from 0 004 0 06 g/ml against Neisseria gonorrhoeae isolates Based on these pharmacological properties cefoperazone sodium salt holds research potential in experimental infection models to investigate bacterial susceptibility resistance mechanisms and pharmacokinetic properties in clinical microbiology and infectious diseases
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 2mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
TARGETMOL CHEMICALS INC Cloprostenol sodium salt 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water-soluble, crystalline form of cloprostenol compared to the free acid and is a synthetic analog of prostaglandin F2alpha. Purity 98%
Selleck Chemical LLC Nigericin sodium salt
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that works by acting as an H K and Pb2 ionophore Nigericin can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes
Apexbio Technology LLC 8-CPT-2Me-cAMP, sodium salt 634207-53-7 5mg
8-CPT-2Me-cAMP sodium salt (CAS 634207-53-7) is a selective agonist of exchange proteins directly activated by cAMP (EPACs) which are key intracellular cAMP sensors acting as guanine nucleotide exchange factors for Rap1 and Rap2 This compound effectively activates EPAC1 leading to increased Rap1 activity and enhanced cell adhesion particularly in the presence of MAP1A light chain 2 In Jurkat T cells 8-CPT-2Me-cAMP induces Rap1 activation independently of PKA inhibition In prostate cancer cell models it dose-dependently upregulates Epac1 phosphorylated Akt and stimulates mTORC1/mTORC2 signaling It is widely utilized to dissect EPAC-specific pathways in cell signaling adhesion and proliferation studies
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 500mg
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics
Selleck Chemical LLC Isethionic acid sodium salt
Isethionic acid sodium salt is an amphoteric detergent used in detergent bar soaps
Apexbio Technology LLC CX-4945 sodium salt 1309357-15-0 10mg
CX-4945 sodium salt (Silmitasertib sodium salt CAS 1309357-15-0) is a potent and selective inhibitor of casein kinase 2 (CK2) effectively targeting both the CK2 and CK2 catalytic subunits By inhibiting CK2 activity CX-4945 disrupts signaling pathways involved in cell cycle progression transcriptional regulation and cell survival The compound exhibits oral bioavailability and is widely utilized in research focused on tumor biology mechanistic studies of signaling cascades and the functional characterization of protein kinases
Medchemexpress LLC NADP disodium salt | 24292-60-2 | 98.8% | 789.39 | 1 ML
NADP disodium salt is a coenzyme involved in cellular electron transfer reactions in biological metabolism. It maintains cellular redox homeostasis, regulates many biological events, and provides reducing ability for synthetic metabolic reactions and redox balance. NADPH, derived from NADP, plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes.
- Disodium salt form of NADP.
- Coenzyme involved in cellular electron transfer reactions.
- Alternately oxidized (NADP+) and reduced (NADPH).
- Maintains cellular redox homeostasis.
- Regulates many biological events, including cellular metabolism.
- NADPH is a universal electron donor.
- Provides reducing ability for synthetic metabolic reactions and redox balance.
- Regulates inflammation, redox homeostasis, and synthetic metabolism processes.
Apexbio Technology LLC Rifamycin sodium salt 14897-39-3 25mg
Rifamycin sodium salt (14897-39-3) is a small-molecule inhibitor targeting bacterial RNA polymerase It is designed to inhibit RNA synthesis thereby suppressing bacterial growth Rifamycin sodium salt exerts its biological activity primarily through inhibition of bacterial RNA polymerase In cellular assays evaluating antibacterial potency Rifamycin sodium salt demonstrates inhibitory activity with IC50 values typically in the micromolar to submicromolar concentration range depending on bacterial strains and experimental conditions Based on these pharmacological properties Rifamycin sodium salt holds research potential in studies of bacterial transcription mechanisms antibiotic resistance pathways and the screening of antimicrobial compounds
ILEX LIFE SCIENCES LLC ALSEVERS SOLUTION 1000 ML
PAN-Biotech Alsever's Solution (1000 ml). Ca/Mg: Without calcium and magnesium. BICARBONATE: Without sodium bicarbonate. PHENOL RED: Without Phenol Red. STERILE: Yes. STORAGE: +2-8°C. PRODUCT CATEGORY: Balanced salt solutions. MANUFACTURER: PAN-Biotech GmbH. COUNTRY OF ORIGIN: Germany. DESCRIPTION: PAN-Biotech Alsever's Solution is an isotonic balanced solution. It is used as an anticoagulant or blood preservative. Alsever's Solution enables whole blood to be stored at refrigerator temperature up to 10 weeks.
Apexbio Technology LLC Concanavalin A (Con A)-HyperFluor 594 5mg(5 mg/mL)
Concanavalin A (Con A) derived from Canavalia ensiformis (jack bean) is a plant lectin protein with a molecular weight of approximately 104 kDa Each subunit can bind one Ca2 ion and one Mn2 ion and has one carbohydrate binding site Con A is capable of binding to various glycoproteins glycolipids and -D-glucose and -D-mannose residues HyperFluor 594 is a fluorescent dye that emits green fluorescence under UV light (Ex/Em 590 nm/617 nm) This conjugation significantly enhances the visualization capability of Con A-HyperFluor 594 for detecting carbohydrate molecules on the cell surface This product is a solution-form Concanavalin A labeled with HyperFluor 594 It is applicable in glycobiology research serving as a probe to detect carbohydrate molecules on the cell surface and analyzed effectively using flow cytometry Applying IHC staining procedures with this product allows visualization of carbohydrate distribution in tissues or cells under a fluorescence microscope