Dicarboxylic acids and derivatives
Medchemexpress LLC RG-101 sodium | 00-00-0 | 95.4% | 8537.6 (free acid) | C295H410N78Na19O146P19S17 | 5 MG
RG-101 sodium is a hepatocyte-targeted N-acetylgalactosamine (GalNAc)-conjugated antisense oligonucleotide that antagonizes microRNA-122 (miR-122), a host factor important for hepatitis C virus replication. Supplied as a sodium salt, it is used in research to study miR-122 biology and antiviral mechanisms.
- Hepatocyte-targeted GalNAc conjugate for liver delivery.
- Antagonizes miR-122 to modulate hepatitis C virus-related pathways.
- High molecular weight oligonucleotide for sequence-specific activity.
- High purity (95.4%) suitable for research applications.
- Soluble in water; sonication may be required for dissolution.
- Recommended storage at -20°C; in solution store at -80°C for long-term.
Medchemexpress LLC AVN-101 hydrochlorid 5mg | 1061354-48-0 | 340.89 g/mol | C21H25ClN2 | 5 MG
AVN-101 hydrochloride is a brain-penetrant, orally active 5-HT7 receptor antagonist used in pharmacological research. Supplied as a 5 mg powder with high purity, it is suitable for in vitro assays and preclinical studies requiring selective serotonergic modulation.
- High purity suitable for research applications.
- Brain-penetrant profile for central nervous system studies.
- Orally active salt form compatible with dosing studies.
- Stable powder for sealed, low-temperature storage.
- Small packaging appropriate for early-stage research.
Selleck Chemical LLC MZ-101-E1913-25MG
MZ-101 (GYS1-IN-2) is a potent small molecule inhibitor of Glycogen synthase 1(GYS1) with an IC50 value of 0 041 M By depleting muscle glycogen MZ-101 treatment normalizes glycogen levels and corrects transcriptional and metabolic abnormalities in Pompe mice
Medchemexpress LLC Sulforhodamine 101 DHPE | 187099-99-6 | >95.0% | 1381.84 | C74H117N4O14PS2 | 1MG
Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.
![Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247159.png-250.jpg)
Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG
CUDC-101 is a small-molecule research compound that concurrently inhibits histone deacetylases (HDACs) and receptor tyrosine kinases EGFR and HER2. It is used in preclinical cancer research to study combined epigenetic and kinase-targeted therapies.
- Potent inhibition of HDAC, EGFR, and HER2 with IC50s of 4.4 nM, 2.4 nM, and 15.7 nM.
- Contains a hydroxamic acid moiety associated with HDAC activity.
- High purity (>98.0%) suitable for research applications.
- Soluble in DMSO at 25 mg/mL (approximately 57.54 mM; may require ultrasonic agitation).
- Molecular formula C24H26N4O4 and molecular weight 434.49 g/mol.
Medchemexpress LLC Lei-101 hydrochloride | 2250025-91-1 | 99.4% | 508.99 | C23H26ClFN4O4S | 100MG
LEI-101 is a potent, selective cannabinoid CB2 receptor agonist used for biochemical and pharmacological research. It shows high selectivity for CB2 over CB1, is orally bioavailable, and is supplied as a solid for laboratory studies. Intended for research use only (not for human use).
- Selective CB2 receptor agonist with approximately 100-fold selectivity over CB1.
- Orally bioavailable, suitable for in vivo pharmacology studies.
- High purity (99.35%).
- Molecular weight 508.99 and formula C23H26ClFN4O4S.
- Soluble in DMSO (approx. 116.7 mg/mL).
- Intended for laboratory research use only, not for human consumption.
Medchemexpress LLC AVN-101 hydrochlorid 25mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 25 MG
AVN-101 hydrochloride is the hydrochloride salt of a brain-penetrant small molecule antagonist of serotonin (5-HT) receptors, supplied for preclinical and in-vitro research. It is provided as a solid with reported high purity for analytical and biological assays.
- Potent antagonist of 5-HT receptor subtypes (5-HT7, 5-HT6, 5-HT2A, 5-HT2C).
- High purity: 99.59%.
- Molecular formula C21H25ClN2; molecular weight 340.89.
- Available in small research pack sizes, including 25 MG.
- Provided as hydrochloride salt to improve solubility for assay preparation.
- For research use only; not for human or veterinary use.
Medchemexpress LLC VNT-101 | 2894060-67-2 | 99.5% | 456.41 | 5 MG
VNT-101 is an orally active influenza A (IAV) inhibitor that disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex. It exhibits potent antiviral activity across multiple influenza A subtypes and robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. It can be used for the study of influenza A infection.
- Orally active influenza A (IAV) inhibitor.
- Disrupts NP-NP PPI to block NP oligomerization.
- Destabilizes the viral ribonucleoprotein (RNP) complex.
- Potent antiviral activity across multiple influenza A subtypes.
- Exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay.
- Demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus.
Medchemexpress LLC BNC-101 5mg | 5mg
BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
AdipoGen Sulforhodamine 101 acid Cl
Chemical. CAS 82354-19-6. Formula C31H29ClN2O6S2. MW 625.15. Synthetic. Sulforhodamine 101 sulfonyl chloride also called Texas Red sulfonyl chloride is a popular long wavelength amine-reactive rhodamine dye. Because the dye is quite unstable in water, reactions with amines in an aqueous solution must be carried out at low temperature over ice or at 4°C and usually at pH 8.5.
Medchemexpress LLC UK-101 | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 1 MG
UK-101 is a selective small-molecule inhibitor of the immunoproteasome β1i (LMP2) subunit used in biochemical and cellular research to probe immunoproteasome function and induce apoptosis in certain cancer models.
- Selective LMP2 (β1i) inhibitor with reported IC50 of 104 nM.
- Shows ~144-fold selectivity versus β1c and ~10-fold versus β5.
- High reported purity (99.58%) suitable for research applications.
- Molecular weight 484.74 g·mol⁻¹ and formula C25H48N2O5Si.
- Soluble in DMSO and supplied in small research quantities, including 1 mg packs.
