Fumonisins
Apexbio Technology LLC Demethylasterriquinone B1(Synonyms: Demethylasterriquinone B-1, DMAQ-B1, Demethylasterriquinone-B1, DMAQ B1, Demethylasterriquinone derivative B1), 5mg, CAS: 78860-34-1.
Demethylasterriquinone B1 (CAS 78860-34-1) is a selective insulin receptor (IR) agonist that acts by promoting tyrosine phosphorylation within the insulin receptor -subunit This phosphorylation event subsequently activates downstream signaling pathways particularly phosphatidylinositol 3-kinase (PI3K) and AKT Demethylasterriquinone B1 has utility as a research tool for investigating insulin signaling cascades glucose metabolism and related metabolic regulatory mechanisms thus facilitating studies aimed at understanding insulin sensitivity and metabolic diseases
Apexbio Technology LLC Fumonisin B1(Synonyms: FB1, Fumonisin-B1, Fusarium Moniliforme toxin B1, Macrofusine, Fusariotoxin B1), 10mg, CAS: 116355-83-0.
Fumonisin B1 (CAS 116355-83-0) is a mycotoxin isolated from the fungus Fusarium moniliforme It potently inhibits sphingosine N-acyltransferase (ceramide synthase) an enzyme critical to sphingolipid biosynthesis leading to the intracellular accumulation of sphingoid bases (IC 75 nM) Additionally Fumonisin B1 exhibits inhibitory activity against several protein phosphatases notably PP5 PP2C PP2A PP1 2 and PP2B with IC ranging from approximately 80 M (PP5) to 3000 M (PP2B) This compound is employed in biomedical research to investigate sphingolipid metabolism cell signaling and phosphatase-related cellular processes
Cayman Chemical FumonIsIn B1 1mg
A mycotoxin; inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme); induces DNA fragmentation and apoptosis in CV-1 cells at 5 and 25 µM, respectively; cytotoxic to primary rat hepatocytes; induces hepatocyte nodule formation, a marker of cancer initiation, in rats at 500 mg/kg for 21 days; has been detected in corn and corn-based foods and livestock feeds
Medchemexpress LLC Carboxypeptidase B1/ 100ug | 100ug
Carboxypeptidase B1/CPB1 Protein Human (HEK293 His) is an approximately 47 0 kDa carboxypeptidase B1 protein with a C-terminal His-flag
Apexbio Technology LLC Fumonisin B1(Synonyms: FB1, Fumonisin-B1, Fusarium Moniliforme toxin B1, Macrofusine, Fusariotoxin B1), 5mg, CAS: 116355-83-0.
Fumonisin B1 (CAS 116355-83-0) is a mycotoxin isolated from the fungus Fusarium moniliforme It potently inhibits sphingosine N-acyltransferase (ceramide synthase) an enzyme critical to sphingolipid biosynthesis leading to the intracellular accumulation of sphingoid bases (IC 75 nM) Additionally Fumonisin B1 exhibits inhibitory activity against several protein phosphatases notably PP5 PP2C PP2A PP1 2 and PP2B with IC ranging from approximately 80 M (PP5) to 3000 M (PP2B) This compound is employed in biomedical research to investigate sphingolipid metabolism cell signaling and phosphatase-related cellular processes
Medchemexpress LLC Bafilomycin B1 | 88899-56-3 | 5 MG
Bafilomycin B1 is a macrolide antibiotic isolated from the mycelium of Streptomyces gresuis. It is a structural analog of Bafilomycin A1 and functions as an inhibitor of V-ATPase. This compound has demonstrated neuroprotective properties against Chloroquine-induced cell death. Furthermore, Bafilomycin B1 significantly inhibits the accumulation of lipid droplets induced by oxidized low-density lipoprotein (LDL).
- Macrolide antibiotic: derived from Streptomyces gresuis mycelium.
- V-ATPase inhibitor: acts as an inhibitor of V-ATPase, a key enzyme involved in various cellular processes.
- Neuroprotective effects: provides neuroprotection against Chloroquine-induced neuronal death.
- Lipid accumulation inhibition: significantly reduces the accumulation of lipid droplets induced by oxidized LDL.
- Structural analog: shares structural similarities with Bafilomycin A1.
Medchemexpress LLC Fumonisin B2 | 116355-84-1 | 500 UG
Fumonisin B2 is a selective ceramide synthase inhibitor and carcinogenic mycotoxin. It inhibits de novo sphingolipid biosynthesis by blocking amide bond formation, leading to altered sphingolipid levels, inhibition of cell proliferation, and induction of cell death. This product is utilized to investigate the pathogenesis of diseases associated with *Fusarium verticillioides* contamination.
- Selective ceramide synthase inhibitor and carcinogenic mycotoxin.
- Inhibits de novo sphingolipid biosynthesis.
- Used for investigating diseases related to *Fusarium verticillioides* contamination.
- Demonstrates inhibition of cell proliferation in vitro.
- Shows effects on body weight, food consumption, and serum markers in vivo.
- Induces cellular changes in liver and kidney in animal models.
Medchemexpress LLC Carboxypeptidase B1/ 10ug
Carboxypeptidase B1/CPB1 protein is part of the PDGF/VEGF growth factor family and has the same structural and functional characteristics as proteins that affect cell growth proliferation and angiogenesis This family is critical for mediating endothelial cell responses and promoting blood vessel formation including VEGF-C which is involved in lymphangiogenesis Carboxypeptidase B1/CPB1 Protein Mouse (HEK293 His) is the recombinant mouse-derived Carboxypeptidase B1/CPB1 protein expressed by HEK293 with C-His labeled tag
Sigma Aldrich Fine Chemicals Biosciences Fumonisin B1 from Fusarium moniliforme >=98% (HPLC) | 116355-83-0 | MFCD27977580 | 10MG
Fumonisin B1 from Fusarium moniliforme >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 721.83 | 116355-83-0 | MFCD27977580 | 10MG
Medchemexpress LLC Ephrin-B1/EFNB1 Rat 5ug
Ephrin-B1/EFNB1 proteins bind to Eph receptors on neighboring cells and promote bidirectional signaling in developing neurons blood vessels and epithelia It has high affinity for EPHB1/ELK also binds EPHB2 and EPHB3 and induces commissural axon/growth cone collapse Ephrin-B1/EFNB1 Protein Rat (HEK293 His) is the recombinant rat-derived Ephrin-B1/EFNB1 protein expressed by HEK293 with C-His labeled tag