Fumonisins
Selleck Chemical LLC Fumonisin B1
Fumonisin B1 is a mycotoxin produced by Fusarium moniliforme Sheldon and a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) an enzyme vital for the de novo synthesis of sphingolipids It exhibits an IC50 of 0 1 M for N-acyltransferase (ceramide synthase) in rat liver microsomes and also reduces the conversion of [3H]sphingosine to [3H]ceramide in intact hepatocytes
Medchemexpress LLC Carboxypeptidase B1/ 100ug | 100ug
Carboxypeptidase B1/CPB1 Protein Human (HEK293 His) is an approximately 47 0 kDa carboxypeptidase B1 protein with a C-terminal His-flag
Medchemexpress LLC Procyanidin B1 | 20315-25-7 | 578.52 | 1 MG
Procyanidin B1 is a polyphenolic flavonoid isolated from commonly eaten fruits. It binds to the TLR4/MD-2 complex and exhibits anti-inflammatory activity. It is for research use only.
- Polyphenolic flavonoid isolated from fruits and fruit juices
- Binds to TLR4/MD-2 complex
- Possesses anti-inflammatory activity
- Causes cellular toxicity at concentrations >100 μg/mL
- Inhibits LPS-induced TNF-α production and expression of MD-2, TRAF6, NF-κB mRNA, phosphorylated p38 MAPK, and NF-κB protein in THP1 cells at 100 μg/mL
- Protects against Aβ oligomer-induced neuronal death at 50-100 μM
- Potently inhibits the activation of caspase-3 at 100 μM, caspase-8 at 30, 50, and 100 μM, and caspase-9 at 10, 30, 50, and 100 μM
- Significantly and dose-dependently induces expression of ACO and CPT1 at 10, 20, 30 μM, with no obvious effect on mRNA expression of PPARα
Medchemexpress LLC Ephrin-B1/EFNB1 Rat 500ug
Ephrin-B1/EFNB1 proteins bind to Eph receptors on neighboring cells and promote bidirectional signaling in developing neurons blood vessels and epithelia It has high affinity for EPHB1/ELK also binds EPHB2 and EPHB3 and induces commissural axon/growth cone collapse Ephrin-B1/EFNB1 Protein Rat (HEK293 His) is the recombinant rat-derived Ephrin-B1/EFNB1 protein expressed by HEK293 with C-His labeled tag
Cayman Chemical Fumonisin B1, Purity: ≥95%, CAS: 116355-83-0, 1 mg
A mycotoxin; inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme); induces DNA fragmentation and apoptosis in CV-1 cells at 5 and 25 µM, respectively; cytotoxic to primary rat hepatocytes; induces hepatocyte nodule formation, a marker of cancer initiation, in rats at 500 mg/kg for 21 days; has been detected in corn and corn-based foods and livestock feeds
Medchemexpress LLC Polymyxin b1 | 4135-11-9 | 98.9% | C56H98N16O13 | 5 MG
Polymyxin B1 is a potent antimicrobial lipopeptide initially derived from *Bacillus polymyxa*. It is identified as the major component within Polymyxin B and is capable of inducing the lysis of bacterial cells by interacting with their membranes. This compound shows promise for the treatment of multidrug-resistant Gram-negative bacterial infections.
- Potent antimicrobial lipopeptide
- Induces bacterial cell lysis
- Potential for treating multidrug-resistant Gram-negative bacterial infections
- Available in solid form
- High purity
- Comprehensive documentation
- Good storage stability
Medchemexpress LLC HY-N6719 1mg Medchemexpress, Fumonisin B1 CAS:116355-83-0 Purity:>98%
Medchemexpress, HY-N6719 1mg Fumonisin B1 CAS:116355-83-0 Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ephrin Receptor B1 antibody (YA2176) | 10 UL
Ephrin Receptor B1 antibody (YA2176) is intended for laboratory chemicals and the manufacture of substances. This product is for research use only and should only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities.
- Host: Rabbit
- Reactivity: Human, mouse, rat
- Clonality number: YA2176
- SwissProt ID: P54762
- Gene ID: 2047
- Appearance: Liquid
- Concentration: 0.3 mg/mL
- Conjugation: Non-conjugated
- Applications: WB, IP
- Dilution ratio: WB: 1:500-1:1000; IP: 1:50
- Formulation: Supplied in rabbit IgG in 10 mM PBS, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
- Storage and stability: Stored at -20 °C for 1 year; avoid repeated freeze/thaw cycles.
- Shipping: With blue ice
Apexbio Technology LLC Fumonisin B1(Synonyms: FB1, Fumonisin-B1, Fusarium Moniliforme toxin B1, Macrofusine, Fusariotoxin B1), 1mg, CAS: 116355-83-0.
Fumonisin B1 (CAS 116355-83-0) is a mycotoxin isolated from the fungus Fusarium moniliforme It potently inhibits sphingosine N-acyltransferase (ceramide synthase) an enzyme critical to sphingolipid biosynthesis leading to the intracellular accumulation of sphingoid bases (IC 75 nM) Additionally Fumonisin B1 exhibits inhibitory activity against several protein phosphatases notably PP5 PP2C PP2A PP1 2 and PP2B with IC ranging from approximately 80 M (PP5) to 3000 M (PP2B) This compound is employed in biomedical research to investigate sphingolipid metabolism cell signaling and phosphatase-related cellular processes
Medchemexpress LLC Ephrin-B1/EFNB1 Mou 5ug
Ephrin-B1 (EFNB1) protein binds to Eph family receptors enabling signaling between receptor-expressing cells and cells with EFNB1 It is crucial for neuronal axon growth and expressed in various tissues like the adult lung and colon highlighting its widespread presence and importance in mediating cellular interactions Ephrin-B1/EFNB1 Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Ephrin-B1/EFNB1 protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Fumonisin B1 | 116355-83-0 | MFCD27977580 | 5 MG
Fumonisin B1 | 116355-83-0 | MFCD27977580 | 5 MG