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Filtered Search Results
Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000559088 NF-KAPPA-B1 P105/P50 D4P4D RAB
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000559528 NF-KAPPA-B1 P105/P50 D4P4D RAB
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000560391 NF-KAPPA-B1 P105/P50 D4P4D RAB
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000561422 NF-KAPPA-B1 P50 F8H1O RABBIT M
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000561423 NF-KAPPA-B1 P50 F8H1O RABBIT M
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Medchemexpress LLC Isofraxidin | 486-21-5 | 222.19 | 5 MG
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Isofraxidin, a coumarin component from *Acanthopanax senticosus*, inhibits MMP-7 expression and cell invasion of human hepatoma cells. It inhibits the phosphorylation of ERK1/2 in hepatoma cells and attenuates the expression of iNOS and COX-2. Additionally, Isofraxidin inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation.
- Inhibits MMP-7 expression and cell invasion
- Inhibits phosphorylation of ERK1/2
- Attenuates expression of iNOS and COX-2
- Inhibits TLR4/MD-2 complex formation
- Purity: 99.94%
- Appearance: Solid, off-white to yellow color
- Soluble in DMSO: 250 mg/mL
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Medchemexpress LLC 8-Epidiosbulbin E acetate | 91095-48-6 | 5 MG
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8-Epidiosbulbin E acetate is a furanoid abundant in Dioscorea bulbifera L.. It demonstrates broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. Intended for research use only, it can also be utilized in animal modeling to create liver injury models. Its hepatotoxicity is attributed to an electrophilic intermediate generated by metabolic activation of the furan ring, mediated by cytochromes P450, primarily damaging hepatic cells through aberrant regulation of bile acid metabolism, and taurine and hypotaurine metabolism.
- Furanoid found in Dioscorea bulbifera L.
- Exhibits broad-spectrum plasmid-curing activity against MDR bacteria
- Can be used to create liver injury models in animal studies
- Hepatotoxicity linked to metabolic activation of its furan ring
- Damages hepatic cells by disrupting bile acid, taurine, and hypotaurine metabolism
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Medchemexpress LLC Xylohexaose | 49694-21-5 | 5 MG
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Xylohexaose is a xylooligosaccharide composed of six xylose residues. It is commonly used as a substrate in assays to determine xylan hydrolysis properties and is intended for research use only.
- Composed of six xylose residues
- Used as a substrate in xylan hydrolysis properties assays
- Purity of 99.9%
- Molecular formula C30H50O25
- Molecular weight of 810.70
- Appears as a white to off-white solid
- Derived from microorganisms, fungus Aspergillus flavus
- Store at 4°C, protected from light
- Soluble in H2O at 12.5 mg/mL and PBS at 100 mg/mL
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Medchemexpress LLC Ivarmacitinib | 1445987-21-2 | 99.6% | 414.48 | 10 MG
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Ivarmacitinib (SHR0302) is a potent and orally active inhibitor of all members of the JAK family, particularly JAK1. It demonstrates selectivity for JAK1, being >10-fold more selective for JAK2, 77-fold for JAK3, and 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and promotes apoptosis in hepatic stellate cells, exhibiting anti-proliferative and anti-inflammatory properties.
- Potent and orally active JAK family inhibitor.
- Highly selective for JAK1.
- Inhibits JAK1-STAT3 phosphorylation.
- Induces apoptosis in hepatic stellate cells.
- Possesses anti-proliferative effects.
- Exhibits anti-inflammatory effects.
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Medchemexpress LLC Methyl myristate | 124-10-7 | 242.40 | 500 MG
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Methyl myristate is a saturated fatty acid methyl ester produced through the esterification of myristic acid. It demonstrates significant melanin induction in B16F10 melanoma cells and has been shown to reduce acetylcholine and ergot alkaloid-induced uterine contractions in isolated rat uteri, indicating uterine relaxation activity.
- Saturated fatty acid methyl ester
- Produced via esterification of myristic acid
- Induces melanin in B16F10 melanoma cells
- Reduces uterine contractions in isolated rat uteri
- Exhibits uterine relaxation activity
- Liquid appearance
- Colorless to light yellow
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Medchemexpress LLC Methyl heptadecanoate | 1731-92-6 | 284.48 | 100 MG
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Methyl heptadecanoate is a methyl ester derivative of heptadecanoic acid. It serves as an internal standard for the quantitative calibration of fatty acids in GC-MS analysis.
- Methyl ester derivative of heptadecanoic acid
- Used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis
- Appears as a white to off-white solid
- Classified as a lipid
- Initially sourced from animals (bovine tallow)
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Medchemexpress LLC Methyl heptadecanoate-d33 | 1219804-81-5 | MFCD03428281 | 317.68 | 5 MG
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Methyl heptadecanoate-d33 is the deuterium labeled Methyl heptadecanoate (C17:0 methyl ester), which is the methyl ester derivative of heptadecanoic acid. It is used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis.
- Used as an internal standard for quantitative calibration of fatty acids
- Applicable in GC-MS analysis
- Can also be used as a tracer
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC (-)-Epigallocatechin Gallate (EGCG) | 989-51-5 | 99.8% | 458.37 | 500 MG
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(-)-Epigallocatechin Gallate (EGCG) is a major polyphenol found in green tea. It inhibits cell proliferation and induces cell apoptosis, while also inhibiting glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. This compound possesses potent anticancer, antioxidant, and anti-inflammatory properties.
- Inhibits cell proliferation
- Induces cell apoptosis
- Inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity
- Potent anticancer properties
- Antioxidant properties
- Anti-inflammatory properties
- Active against various types of cancers, including colorectal cancer, myeloid leukemia, and thyroid carcinoma
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Aobchem (3 4-Dibromophenyl)boronic acid | ≥97% | CAS 1228180-83-3 | C6H5BBr2O2 | 500mg
(3 4-Dibromophenyl)boronic acid | ≥97% | CAS 1228180-83-3 | C6H5BBr2O2 | 500mg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem (3 4-Dibromophenyl)boronic acid | ≥97% | CAS 1228180-83-3 | C6H5BBr2O2 | 1g
(3 4-Dibromophenyl)boronic acid | ≥97% | CAS 1228180-83-3 | C6H5BBr2O2 | 1g
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More