Pentacarboxylic acids and derivatives
Medchemexpress LLC ODN 1585 (sodium) | DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 1 MG
ODN 1585 (sodium) is a potent inducer of IFN and TNFα production, and a strong stimulator of NK (natural killer) cell function. It increases CD8+ T-cell function, including IFN-γ production. This product has been shown to induce regression of established melanomas and offer complete protection against malaria in mice. It can be used for acute myelogenous leukemia (AML) and malaria research, and also serves as a vaccine adjuvant.
- Potent inducer of IFN and TNFα production
- Strong stimulator of natural killer (NK) cell function
- Increases CD8+ T-cell function and IFN-γ production
- Induces regression of established melanomas
- Confers protection against malaria
- Applicable for acute myelogenous leukemia (AML) and malaria research
- Functions as a vaccine adjuvant
- Induces PBMC to produce IFN-α
- Stimulates NK cell-mediated lysis of K562 cells
Medchemexpress LLC ODN 1585 sodium | DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 5 MG
ODN 1585 sodium is a potent inducer of IFN and TNFα production, a strong stimulator of NK (natural killer) function, and enhances CD8+ T-cell function. It has demonstrated efficacy in inducing regression of established melanomas and protecting against malaria in mice. This compound is valuable for research in acute myelogenous leukemia (AML) and malaria, and can also serve as a vaccine adjuvant.
- Potent inducer of IFN and TNFα production
- Potent stimulator of NK (natural killer) function
- Increases CD8+ T-cell function and IFN-γ production
- Induces regression of established melanomas in mice
- Confers complete protection against malaria in mice
- Useful for acute myelogenous leukemia (AML) and malaria research
- Serves as a vaccine adjuvant
- Stimulates NK cell-mediated lysis of K562 cells in vitro
Medchemexpress LLC ODN 1585 | 386832-46-8 | DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G) | 1 MG
ODN 1585 is a potent inducer of IFN and TNFα production and a strong stimulator of NK (natural killer) function. It increases CD8+ T-cell function, including the CD8+ T cell-mediated production of IFN-γ. ODN 1585 has been shown to induce regression of established melanomas in mice and can confer complete protection against malaria in mice. It is used for acute myelogenous leukemia (AML) and malaria research, and can also serve as a vaccine adjuvant.
- Potent inducer of IFN and TNFα production
- Potent stimulator of NK (natural killer) function
- Increases CD8+ T-cell function, including IFN-γ production
- Induces regression of established melanomas in mice
- Confers complete protection against malaria in mice
- Can be used for acute myelogenous leukemia (AML) and malaria research
- Can be used as a vaccine adjuvant
Medchemexpress LLC Oligodeoxynucleotide ODN 1585 (sodium salt) | 92.5% | 6430 (free acid) | DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G) | 10 MG
ODN 1585 sodium is a synthetic CpG-containing oligodeoxynucleotide (sodium salt) used as an immunostimulatory reagent in research. It potently induces interferon and TNFα, enhances NK and CD8+ T-cell responses, and has applications in vaccine adjuvant studies and disease models such as acute myelogenous leukemia and malaria. Supplied as a white to off-white solid; sequence and analytical data are provided by the manufacturer.