Tricarboxylic acids and derivatives
Medchemexpress LLC Azido-PEG2-CH2COOH | 882518-90-3 | 99.03% | 189.17 | 1 ML
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs use the intracellular ubiquitin-proteasome system to degrade target proteins.
- PEG-based PROTAC linker.
- Click chemistry reagent.
- Contains an Azide group for CuAAc reaction with Alkyne groups.
- Can undergo SPAAC reactions with DBCO or BCN groups.
eMolecules 1204918-73-9 | Medchem Express | (E/Z)-Zotiraciclib (citrate) | 5mg | 716993856 | HY-15166B | 564.595 | C29H32N4O8
Ambeed | 4-Pyrrolidin-2-ylpyridine | 250mg | 552520275 | A104385 | 128562-25-4 | MFCD01862536 | 148.209 | C9H12N2
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Selleck Chemical LLC Tamoxifen Citrate S1972-1g
Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity Tamoxifen induces apoptosis and autophagy
Accela Chembio Inc Tri-o-acetyl-d-glucal | 25g | 2873-29-2 | MFCD00063253 | 97+% | Shelf Life: 720 Days | Light Sensitive
Tri-o-acetyl-d-glucal | 25g | 2873-29-2 | MFCD00063253 | 97+% | Shelf Life: 720 Days | Light Sensitive
Chemscene ChemScene | Tris(4-(trifluoromethyl)phenyl)phosphine | 25G | CS-W011542 | 0.98 | 13406-29-6| MFCD00058883 | 466.28
ChemScene | Tris(4-(trifluoromethyl)phenyl)phosphine | 25G | CS-W011542 | 0.98 | 13406-29-6| MFCD00058883 | 466.28
Medchemexpress LLC Sparfosic acid trisodium | 70962-66-2 | MFCD32693867 | 98.0% | 321.06 g/mol | C6H7NNa3O8P | 5 MG
Sparfosic acid trisodium (CAS 70962-66-2) is a research-grade DNA antimetabolite that potently inhibits aspartate transcarbamoyl transferase (ATCase). Supplied as the trisodium salt, it is used in biochemical and cell-based studies to probe pyrimidine biosynthesis and to assess synergistic cytotoxic effects in combination with chemotherapeutic agents.
- Potent ATCase inhibitor for studying pyrimidine biosynthesis.
- 98.0% purity suitable for research applications.
- Supplied as the trisodium salt in solid powder form.
- Available in small pack sizes (5 mg-100 mg) and as 10 mM in DMSO solution.
- Molecular weight 321.06 g/mol; formula C6H7NNa3O8P.
- Useful in cell-based assays to evaluate synergy with chemotherapeutics.
Medchemexpress LLC CH2COOH-PEG3-CH2COOH | 32775-08-9 | 99.1% | 5 G
CH2COOH-PEG3-CH2COOH is a PEG-based linker bearing two terminal carboxylic acid groups used as a building block in the chemical synthesis of Proteolysis Targeting Chimeras (PROTACs) and other conjugates for research.
- Provides two terminal carboxylic acids for covalent or amide coupling
- Peg3 spacer enhances solubility and flexibility in conjugates
- High listed purity suitable for research use
- Molecular weight 266.25; chemical formula C10H18O8
- Available in small-scale packages for synthetic work
Medchemexpress LLC Icerguastat (Sephin1) | 951441-04-6 | 99.93% | 196.64 | 10 MG
Icerguastat (Sephin1) is a Guanabenz derivative that selectively inhibits the phosphatase regulatory subunit PPP1R15A (R15A). It functions by inhibiting eIF2α dephosphorylation, which prolongs the protective cellular response and demonstrates an anti-prion effect.
- Selectively inhibits the phosphatase regulatory subunit PPP1R15A (R15A).
- Inhibits eIF2α dephosphorylation, extending protective cellular responses.
- Demonstrates anti-prion effects in models.
- Prolongs eIF2α phosphorylation in stressed oligodendrocytes.
- Delays the onset of experimental autoimmune encephalomyelitis (EAE) in animal models.
- Prolongs survival in prion-infected mice.