Tricarboxylic acids and derivatives
Medchemexpress LLC Citrate synthase | 9027-96-7 | MFCD00131495 | ~98 KDa dimer | 250 U
Citrate synthase catalyzes the first reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is localized within eukaryotic cells in the mitochondrial matrix.
- Catalyzes the first reaction of the citric acid cycle
- Condenses acetyl-CoA and oxaloacetate to form citrate
- Localized in the mitochondrial matrix
- Specific activity: ≥100 U/mg protein
- Appearance: Colorless to light yellow liquid
- Source: Microorganism
Medchemexpress LLC (E/Z)-Zotiraciclib hydrochloride | 1321626-25-8 | C23H25ClN4O | 5 MG
(E/Z)-Zotiraciclib ((E/Z)-TG02) is an orally active inhibitor of CDK2, JAK2, and FLT3 with IC50s of 13, 73, and 56 nM, respectively. It effectively inhibits the proliferation of cancer cells, making it suitable for cancer research.
- Orally active inhibitor of CDK2, JAK2, and FLT3
- Inhibits proliferation of cancer cells
- Useful for cancer research
- Potently inhibits the CDK2 biomarker pRb
Selleck Chemical LLC Zoledronic acid monohydrate S5244-25mg
Zoledronic acid (Zoledronate CGP-4244) monohydrate a nitrogen-containing bisphosphonate is a potent osteoclast inhibitor which induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho
eMolecules Ambeed / Tris(4-methoxyphenyl)amine / 250mg / 627733411 / A218053 / / 13050-56-1 / MFCD00854211 / 335.403 / C21H21NO3
Ambeed / Tris(4-methoxyphenyl)amine / 250mg / 627733411 / A218053 / / 13050-56-1 / MFCD00854211 / 335.403 / C21H21NO3
Strem, An Ascensus Company CAS# 51805-45-9. 25g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469
CAS# 51805-45-9. 25g. Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP. MFCD00145469. Molecular Weight: 286.65. Molecular Formula: (HOOCCH2CH2)3PH+Clae. Color/form: white xtl. Strem# 15-7400. http://www.strem.com/catalog/v/15-7400/
Medchemexpress LLC Arl67156 trisodium hydrate | 99.9% | 834.61 | C15H23Br2N5Na3O13P3 | 5 MG
ARL67156 trisodium hydrate is the trisodium hydrate salt form of ARL67156, a selective small-molecule inhibitor of ecto-ATPase enzymes including NTPDase1 (CD39), NTPDase3, and NPP1. Supplied as a white to off-white solid, it is intended for research use in studies of purinergic signaling, inflammation, and cardiovascular or respiratory disease models.
- Selective inhibitor of ecto-ATPase enzymes, including NTPDase1 (CD39), NTPDase3, and NPP1.
- Reported Kis values in the low micromolar range for primary targets.
- Demonstrated activity in cellular and tissue assays such as potentiation of neurogenic contractions and modulation of neurotransmitter release.
- High reported purity (99.94%), suitable for biochemical and cellular research.
- Supplied as a solid, white to off-white, available in small research quantities.
TARGETMOL CHEMICALS INC SPD-473 citrate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SPD-473 citrate (BTS 74398 citrate) is a dopamine reuptake inhibitor, a norepinephrine transporter protein (NET) inhibitor, and a 5-hydroxytryptamine reuptake inhibitor, and is used in the study of neurological disorders and endocrine and metabolic diseases. Purity 99.37%
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 100 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker; one binds to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Peg-based protac linker
- Used in the synthesis of protacs
- Enables selective degradation of target proteins
Medchemexpress LLC Butamirate citrate | 18109-81-4 | MFCD00315222 | 99.9% | 499.6 g/mol | C24H37NO10 | 5 MG
Butamirate citrate is an orally active antitussive research compound supplied as the citrate salt. It acts centrally to suppress cough and has reported bronchodilatory and anti-inflammatory effects. Provided as a high-purity analytical standard for research use only.
- Orally active antitussive agent suitable for research.
- High purity analytical standard for assay and method development.
- Reported bronchodilatory and anti-inflammatory properties.
- Available in small packaged quantities for laboratory use.
- For research use only; not for human or clinical use.
eMolecules Lithium citrate tribasic tetrahydrate | 6080-58-6 | MFCD00150030 | 25g
Chem-Impex | Lithium citrate tribasic tetrahydrate | 25g | 322124119 | 30597 | | 6080-58-6 | MFCD00150030 | 281.980 | C6H13Li3O11
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Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 50 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize two ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- Other ligand binds to the target protein
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- High solubility in DMSO (100 mg/mL)
Teknova 1mM Sodium Citrate, pH 6.4, 1000mL, Endotoxin Tested. Sterile. 8 pack.
Sodium citrate solution is a commonly used reagent in life science. It has many uses, such as making media for the growth of microorganisms, lysing cells, and precipitating nucleic acids.
Medchemexpress LLC Adenosine 5'-(α,β-methylene) diphosphate (triammonium) | 99.9% | 476.32 | 25 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor that can be used for research of the ATP-adenosine pathway.
- CD73 inhibitor.
- Can be used for the research of the ATP-adenosine pathway.
- Inhibits 5'-AMP induced adenosine formation in A498 cells (in vitro).
Apexbio Technology LLC Mosapride Citrate 112885-42-4 10mM (in 1mL DMSO)
Mosapride Citrate (CAS 112885-42-4) is a small molecule that functions as a selective agonist of the 5-hydroxytryptamine 4 (5-HT ) receptor and an antagonist of the 5-HT receptor with negligible activity at dopaminergic D adrenergic and as well as 5-HT and 5-HT receptors By modulating serotonin receptor activity it enhances gastrointestinal motility and accelerates gastric emptying Mosapride Citrate is widely used in research investigating serotonergic signaling pathways gut motility regulation and potential therapeutic approaches for gastrointestinal disorders