Tricarboxylic acids and derivatives
Selleck Chemical LLC Ixazomib Citrate (MLN9708) S4432-25mg
Ixazomib Citrate (MLN9708) is a prodrug of Ixazomib (MLN2238) which is a selective orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic ( 5) site with IC50 of 3 4 nM and Ki of 0 93 nM respectively Ixazomib (MLN2238) also inhibits caspase-like ( 1) and trypsin-like ( 2) proteolytic sites with IC50 of 31 nM and 3500 nM respectively
Selleck Chemical LLC Ixazomib Citrate (MLN9708) Analogue S2181-10mM/1mL
Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1 Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238) the biologically active form on exposure to aqueous solutions or plasma Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic ( 5) site of the 20S proteasome with IC50/Ki of 3 4 nM/0 93 nM in cell-free assays less potent to 1 and little activity to 2 Ixazomib (MLN2238) induces autophagy Phase 3
Medchemexpress LLC 2-methylcitric acid trisodium | 117041-96-0 | MFCD16875437 | 96.0% | 272.10 g·mol⁻1 | C7H7Na3O7 | 5 MG
2-Methylcitric acid trisodium is the trisodium salt of 2-methylcitric acid provided as a white to off-white solid for laboratory research. It is an endogenous metabolite used as a marker in methylmalonic and propionic acidemias and is employed in biochemical and mitochondrial studies, where it has been reported to inhibit ADP-stimulated mitochondrial respiration supported by glutamate.
- Trisodium salt, white to off-white solid.
- CAS number 117041-96-0.
- Purity 96.0%.
- Molecular weight 272.10 g·mol⁻1; formula C7H7Na3O7.
- Highly soluble in water (100 mg/mL; may require ultrasonication).
- Storage: sealed at 4°C; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.