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Filtered Search Results
Medchemexpress LLC 5-FORMYLFURAN-2-CARB 50G
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5-FORMYLFURAN-2-CARB 50G
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Chemscene CHEMSCENE
5000578057 1-METHYLBENZIMIDAZOLE 100G
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Medchemexpress LLC 6-CHLOROINDOLE-2-CAR 5G
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6-CHLOROINDOLE-2-CAR 5G
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eMolecules 137081-41-5 | 1-Fluorocyclopropanecarboxylic acid | AA Blocks LLC | MFCD18205954 | 104.080 | C4H5FO2 | 0.000 | OC(=O)C1(F)CC1 | 1g | 410149990
1-Fluorocyclopropanecarboxylic acid | AA Blocks LLC | 137081-41-5 | MFCD18205954 | 104.080 | C4H5FO2 | 0.000 | OC(=O)C1(F)CC1 | 1g | 410149990
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Medchemexpress LLC BI-1622 | 2681392-19-6 | 99.0% | 508.53 | 25 MG
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BI-1622 is a potent and highly selective orally active HER2 (ERBB2) inhibitor. It demonstrates significant selectivity over EGFR and has shown high antitumor efficacy in preclinical studies. The compound exhibits a favorable agent metabolism and pharmacokinetics profile.
- Potent and selective HER2 (ERBB2) inhibitor
- Exhibits an IC50 of 7 nM for HER2
- Shows over 25-fold selectivity for HER2 over EGFR
- Demonstrates high antitumor efficacy in xenograft mouse tumor models
- Features good permeability and no PgP-mediated efflux liability
- Has good in vitro clearance in mouse liver microsomes and hepatocytes
- Inhibits proliferation of HER2-dependent cell lines
- Induces a dose-dependent decrease in pHER2 and pERK levels
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Chemscene CHEMSCENE
5000576285 1H-BENZIMIDAZOLE-6-CARBOXY 25G
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Chemscene CHEMSCENE
5000577780 1H-BENZIMIDAZOLE-6-CARBOXYL 5G
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Chemscene CHEMSCENE
5000578272 1-METHYLBENZIMIDAZOLE 5G
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Ambeed AMBEED
5000869964 METHYL 2-OXOINDOLINE-4-CAR 1GR
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Aobchem Methyl 5-pentylthiophene-2-carboxylate | 95% | CAS 2720607-48-5 | C11H16O2S | 1g
Methyl 5-pentylthiophene-2-carboxylate | 95% | CAS 2720607-48-5 | C11H16O2S | 1g
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Medchemexpress LLC Mizolastine | 108612-45-9 | 99.8% | 50 MG
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Mizolastine is an orally active, high-affinity, and specific peripheral histamine H1 receptor antagonist, classified as a second-generation antihistamine. It effectively inhibits the mRNA expression of VEGF165, VEGF120, TNF-α, and KC. Mizolastine is used in studies related to allergic rhinitis and chronic idiopathic urticaria.
- High-affinity and specific peripheral histamine H1 receptor antagonist
- Effectively inhibits mRNA expression of VEGF165, VEGF120, TNF-α, and KC
- Used in studies of allergic rhinitis and chronic idiopathic urticaria
- Inhibits VEGF, KC, and TNF-α release in mast cells
- Reduces VEGF165, VEGF120, TNF-α, and KC mRNA expression in mast cells
- Inhibits 5-LOX AA metabolite leukotriene B4 (LTB4) production
- Suppresses expression of 5-LOX, cytosolic PLA2 (cPLA2), 5-LOX-activating protein, and LTB4 receptor mRNA
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Medchemexpress LLC Salbutamol (hemisulfate) (standard) | 51022-70-9 | 99.8% | 50 MG
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Salbutamol (Albuterol) hemisulfate (Standard) is an analytical standard intended for research and analytical applications. It is an orally active, short-acting β2-adrenergic receptor agonist. This compound promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway and relaxes bronchial smooth muscle, making it useful for studying bronchospasm induced by asthma and chronic obstructive pulmonary disease.
- Analytical standard for research and analytical applications
- Orally active short-acting β2-adrenergic receptor agonist
- Promotes tumorigenesis in gastric cancer cells through β2-AR/ERK/EMT pathway
- Relaxes bronchial smooth muscle
- Used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease
- Suitable for qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
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Apexbio Technology LLC Mizolastine 108612-45-9 50mg
Mizolastine (CAS 108612-45-9) is a selective antagonist of the histamine H1 receptor exhibiting an inhibitory concentration (IC50) of 47 nM By blocking H1 receptor-mediated signaling Mizolastine effectively attenuates histamine-induced cellular responses involved in allergic inflammation This compound is utilized in biomedical research to investigate mechanisms underlying allergic disorders such as seasonal allergic rhinitis and urticaria and to evaluate therapeutic strategies targeting H1 receptor pathways in allergic and inflammatory conditions
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![eMolecules 7720-39-0 | 2-Aminoimidazole | Accela ChemBio | MFCD00792530 | 83.094 | C3H5N3 | 95.000 | Nc1ncc[nH]1 | 5g | 811174513](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000489370.jpg-250.jpg)
eMolecules 7720-39-0 | 2-Aminoimidazole | Accela ChemBio | MFCD00792530 | 83.094 | C3H5N3 | 95.000 | Nc1ncc[nH]1 | 5g | 811174513
2-Aminoimidazole | Accela ChemBio | 7720-39-0 | MFCD00792530 | 83.094 | C3H5N3 | 95.000 | Nc1ncc[nH]1 | 5g | 811174513
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![eMolecules 7720-39-0 | 2-Aminoimidazole | Ambeed | MFCD00792530 | 83.094 | C3H5N3 | 97.000 | Nc1ncc[nH]1 | 1g | 525876922](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000470313.jpg-250.jpg)
eMolecules 7720-39-0 | 2-Aminoimidazole | Ambeed | MFCD00792530 | 83.094 | C3H5N3 | 97.000 | Nc1ncc[nH]1 | 1g | 525876922
2-Aminoimidazole | Ambeed | 7720-39-0 | MFCD00792530 | 83.094 | C3H5N3 | 97.000 | Nc1ncc[nH]1 | 1g | 525876922
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