Imidazoles

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzonitrile 98.0+%, TCI America™

CAS: 29898-72-4 Molecular Formula: C22H15N3 Molecular Weight (g/mol): 321.383 InChI Key: KGOZFYOJDPVGMV-UHFFFAOYSA-N Synonym: 2-(4-Cyanophenyl)-4,5-diphenylimidazole PubChem CID: 12099795 IUPAC Name: 4-(4,5-diphenyl-1H-imidazol-2-yl)benzonitrile SMILES: C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C#N)C4=CC=CC=C4

Medchemexpress LLC trans-Urocanic acid | 3465-72-3 | 99.9% | 138.12 | 5 G

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trans-Urocanic acid (trans-UCA) is a natural epidermal constituent known for regulating immune function. It inhibits human natural killer cell (NK) activity in vitro and partially inhibits the cytotoxic function of IL-2-activated NK cells. It also reduces IL-2-induced activation of NK cells.

• Natural epidermal constituent
• Inhibits human natural killer cell (NK) activity in vitro
• Regulates immune function
• Partially inhibits cytotoxic function of IL-2-activated NK cells
• Reduces IL-2-induced activation of NK cells

Medchemexpress LLC 2-Propenoic acid, 3-(1H-imidazol-5-yl)-, (2E)- | 3465-72-3 | 99.8% | 138.13 | 1 ML

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trans-urocanic acid (trans-UCA) is a natural epidermal constituent that inhibits human natural killer cell (NK) activity in vitro. It is active in regulating immune function.

• Natural epidermal constituent.
• Inhibits human natural killer cell (NK) activity in vitro.
• Active in regulating an immune function.
• Partially inhibits cytotoxic function of IL-2-activated NK cells and reduces IL-2-induced activation of NK cells.
• Slightly decreases cell proliferation and viability of primary human keratinocytes at 100 μg/mL.

eMolecules​ (2-([(4-METHYL-1H-IMIDAZOL-5-YL)METHYL]THIO)ETHYL)AMINE 2HCL | 38603-72-4 | MFCD12031495 | 1g

AstaTech | (2-([(4-METHYL-1H-IMIDAZOL-5-YL)METHYL]THIO)ETHYL)AMINE 2HCL | 1g | 352254515 | S11912 | 95.000 | 38603-72-4 | MFCD12031495 | 244.180 | C7H15Cl2N3S

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eMolecules​ Ambeed / (E)-3-(1H-Imidazol-5-yl)acrylic acid / 1g / 582615131 / A597870 / / 3465-72-3 / MFCD01593677 / 138.126 / C6H6N2O2

Ambeed / (E)-3-(1H-Imidazol-5-yl)acrylic acid / 1g / 582615131 / A597870 / / 3465-72-3 / MFCD01593677 / 138.126 / C6H6N2O2

Medchemexpress LLC (Z)-Urocanic acid; cis-UCA | 7699-35-6 | 99.9% | 138.12 | 1 ML

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cis-Urocanic acid is a 5-HT2A receptor agonist. It binds to the 5-HT receptor with relatively high affinity (Kd=4.6 nM) and acts as an immune modulator, inducing immunosuppression by binding to the 5-HT2A receptor.

• Target: 5-HT Receptor
• Pathway: GPCR/G Protein; Neuronal Signaling
• In vitro activity: Treatment with 100 μg/mL cis-Urocanic acid completely suppresses IL-6 and IL-8 secretion, decreases caspase-3 activity, and improves cell viability against UV-B irradiation.
• Cell lines for assays: Human corneal epithelial cells (HCE-2) and human conjunctival epithelial cells (HCECs)
• Concentrations for assays: 10, 100, 1,000, and 5,000 μg/mL
• Incubation time for assays: 24, 48, or 72 hours