Dazcapistat is a research-grade calpain inhibitor with reported IC50s of <3 μM for calpain 1, calpain 2, and calpain 9. Supplied as a white to off-white solid with a stated purity of 98.0%, it is intended for in vitro and in vivo research; follow supplier protocols for solubility, formulation, and storage.
- Molecular formula C21H18FN3O4; molecular weight 395.38
- Purity 98.0%
- Appearance white to off-white solid
- In vitro solubility: DMSO 100 mg/mL (ultrasonic recommended)
- In vivo formulation: ≥2.5 mg/mL in recommended vehicle protocols (10% DMSO/40% PEG300/5% Tween-80/45% saline; alternatives available)
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)