Oxazoles
Medchemexpress LLC Pomalidomide-C6-O-C5-O-C4-COOH | 2375774-54-0 | 98.6% | 559.65 g·mol⁻¹ | C29H41N3O8 | 10 MG
Pomalidomide-C6-O-C5-O-C4-COOH is an E3 ligase ligand-linker conjugate that incorporates a pomalidomide-derived cereblon ligand attached to a carboxylated linker. It is intended as a building block for PROTAC synthesis and related protein degradation research. Store sealed, away from moisture, at -20°C; in solvent, store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Useful as an E3 ligase ligand-linker conjugate for PROTAC construction.
- High purity suitable for synthetic applications (98.6%).
- Molecular formula C29H41N3O8 and molecular weight 559.65 g·mol⁻¹.
- Available in small, pre-weighed packages for medicinal chemistry workflows.
- Chemical identification provided via CAS 2375774-54-0.
Apexbio Technology LLC Y-320 288250-47-5 2mg
Y-320 (CAS 288250-47-5) is a phenylpyrazoleanilide small molecule immunomodulator that inhibits interleukin-17 (IL-17) production in CD4 T cells stimulated by IL-15 exhibiting an IC50 of 20 60 nM In vivo oral administration of Y-320 (0 3 3 mg/kg) reduces IL-17 mRNA expression and suppresses the progression of collagen-induced arthritis (CIA) in mice with additional efficacy observed in cynomolgus monkey CIA models Combination with anti-TNF- monoclonal antibody yields a synergistic effect Y-320 serves as a valuable tool for studying IL-17-mediated inflammatory pathways and for preclinical research in rheumatoid arthritis and related autoimmune diseases
Apexbio Technology LLC Y-320 288250-47-5 10mM (in 1mL DMSO)
Y-320 (CAS 288250-47-5) is a phenylpyrazoleanilide small molecule immunomodulator that inhibits interleukin-17 (IL-17) production in CD4 T cells stimulated by IL-15 exhibiting an IC50 of 20 60 nM In vivo oral administration of Y-320 (0 3 3 mg/kg) reduces IL-17 mRNA expression and suppresses the progression of collagen-induced arthritis (CIA) in mice with additional efficacy observed in cynomolgus monkey CIA models Combination with anti-TNF- monoclonal antibody yields a synergistic effect Y-320 serves as a valuable tool for studying IL-17-mediated inflammatory pathways and for preclinical research in rheumatoid arthritis and related autoimmune diseases
Apexbio Technology LLC Y-320 288250-47-5 10mg
Y-320 (CAS 288250-47-5) is a phenylpyrazoleanilide small molecule immunomodulator that inhibits interleukin-17 (IL-17) production in CD4 T cells stimulated by IL-15 exhibiting an IC50 of 20 60 nM In vivo oral administration of Y-320 (0 3 3 mg/kg) reduces IL-17 mRNA expression and suppresses the progression of collagen-induced arthritis (CIA) in mice with additional efficacy observed in cynomolgus monkey CIA models Combination with anti-TNF- monoclonal antibody yields a synergistic effect Y-320 serves as a valuable tool for studying IL-17-mediated inflammatory pathways and for preclinical research in rheumatoid arthritis and related autoimmune diseases
![Medchemexpress LLC 4-(Benzo[d]oxazol-2-yl)aniline | 20934-81-0 | MFCD00453046 | 99.9% | 210.24 | C13H10N2O | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000302850.png-250.jpg)
Medchemexpress LLC 4-(Benzo[d]oxazol-2-yl)aniline | 20934-81-0 | MFCD00453046 | 99.9% | 210.24 | C13H10N2O | 25 G
4-(Benzo[d]oxazol-2-yl)aniline (CAS 20934-81-0) is a small-molecule research compound reported to have antitumor activity, including inhibitory effects against mammary carcinoma cell lines. The product is analytically characterized with HPLC purity reported at 99.93% and has defined storage recommendations to preserve stability.
- High HPLC purity (99.93%) for reliable analytical work.
- Reported antitumor activity against mammary carcinoma cell lines.
- Molecular formula C13H10N2O; molecular weight 210.24.
- Recommended storage: 4°C, protect from light; in solvent: -80°C (up to 6 months), -20°C (1 month).
- Suitable as a research reagent for oncology and related studies.