Pyrazoles

Medchemexpress LLC 1,3-Dimethylpyrazole | 694-48-4 | 96.13 | 25 G

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1,3-Dimethylpyrazole is a bioactive compound isolated from Moso Bamboo Root. It is an active small molecule that can be used as a building block for the synthesis of multiple compounds. Intended for research use only, this substance is a colorless to light yellow liquid.

• Isolated from Moso Bamboo Root
• Active small molecule for chemical synthesis
• Research use only
• Highly flammable liquid and vapor
• Causes skin irritation
• Causes serious eye irritation

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Apexbio Technology LLC DIM-C-pPhOH 151358-47-3 25mg

DIM-C-pPhOH (CAS 151358-47-3) is a small-molecule antagonist that targets the nuclear receptor NR4A1 (nuclear receptor subfamily 4 group A member 1) It has been shown to inhibit tumor cell proliferation by modulating the mTOR signaling pathway induce apoptosis and activate cellular stress responses In in vitro studies using human renal carcinoma cell lines ACHN and 786-O DIM-C-pPhOH demonstrated inhibitory effects on cell proliferation with IC50 values of 13 6 M and 13 0 M respectively This compound serves as a valuable tool for investigating tumor-associated signaling pathways and the mechanisms underlying anticancer therapeutics

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eMolecules​ 7364-25-2 | 3-Indazolinone | Combi-Blocks | MFCD00005685 | 134.138 | C7H6N2O | 95.000 | O=c1[nH][nH]c2ccccc12 | 1g | 290690623

3-Indazolinone | Combi-Blocks | 7364-25-2 | MFCD00005685 | 134.138 | C7H6N2O | 95.000 | O=c1[nH][nH]c2ccccc12 | 1g | 290690623

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eMolecules​ 35344-95-7 | 1H-Pyrazole-4-carboxaldehyde | AA Blocks LLC | MFCD02179514 | 96.089 | C4H4N2O | 0.000 | O=Cc1cn[nH]c1 | 1g | 410168239

1H-Pyrazole-4-carboxaldehyde | AA Blocks LLC | 35344-95-7 | MFCD02179514 | 96.089 | C4H4N2O | 0.000 | O=Cc1cn[nH]c1 | 1g | 410168239

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Accela Chembio Inc 3-amino-6-bromo-1h-indazole | 5g | 404827-77-6 | MFCD05665872 | 97+% | Shelf Life: 1800 Days | Light Sensitive/air Sensitive/+4

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3-amino-6-bromo-1h-indazole | 5g | 404827-77-6 | MFCD05665872 | 97+% | Shelf Life: 1800 Days | Light Sensitive/air Sensitive/+4

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eMolecules​ 858227-11-9 | 6-Methyl-1H-indazole-3-carboxylic acid methyl ester | J & W PharmLab LLC | MFCD09880084 | 190.202 | C10H10N2O2 | 96.000 | COC(=O)c1n[nH]c2cc(C)ccc12 | 5g | 289352084

6-Methyl-1H-indazole-3-carboxylic acid methyl ester | J & W PharmLab LLC | 858227-11-9 | MFCD09880084 | 190.202 | C10H10N2O2 | 96.000 | COC(=O)c1n[nH]c2cc(C)ccc12 | 5g | 289352084

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eMolecules​ 1000340-53-3 | 7-Methyl-1H-indazole-3-carboxylic acid | J & W PharmLab, LLC | MFCD07378884 | 176.175 | C9H8N2O2 | 96.000 | Cc1cccc2c(n[nH]c12)C(O)=O | 1g | 249979947

7-Methyl-1H-indazole-3-carboxylic acid | J & W PharmLab, LLC | 1000340-53-3 | MFCD07378884 | 176.175 | C9H8N2O2 | 96.000 | Cc1cccc2c(n[nH]c12)C(O)=O | 1g | 249979947

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eMolecules​ 694-31-5 | 1,5-Dimethylpyrazole | Combi-Blocks | MFCD01646129 | 96.133 | C5H8N2 | 98.000 | Cc1ccnn1C | 1g | 117534346

1,5-Dimethylpyrazole | Combi-Blocks | 694-31-5 | MFCD01646129 | 96.133 | C5H8N2 | 98.000 | Cc1ccnn1C | 1g | 117534346

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Medchemexpress LLC 3-Nitropyrazole | 26621-44-3 | 113.08 | 10 G

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3-Nitropyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds. The nitro group of 3-Nitropyrazole readily undergoes nucleophilic substitution reactions.

• Biochemical reagent for life science research.
• Organic compound for life science research.
• Nitrogen-containing heterocyclic compound.
• Useful in the synthesis of other active compounds.
• Nitro group readily undergoes nucleophilic substitution reactions.

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Aobchem 6-Indazolyboronic acid, AOBCHEM USA 12393-5G. 885068-10-0. MFCD04972419

6-Indazolyboronic acid, AOBCHEM USA 12393-5G. 885068-10-0. MFCD04972419

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eMolecules​ 13808-64-5 | 4-Bromo-3-methylpyrazole | Ambeed | MFCD00005241 | 161.002 | C4H5BrN2 | 97.000 | Cc1n[nH]cc1Br | 1g | 534082897

4-Bromo-3-methylpyrazole | Ambeed | 13808-64-5 | MFCD00005241 | 161.002 | C4H5BrN2 | 97.000 | Cc1n[nH]cc1Br | 1g | 534082897

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Medchemexpress LLC 2-(pyrimidin-2-yl)benzoic acid | 400892-62-8 | MFCD09999084 | ≥97.0% | 200.20 g·mol⁻¹ | C11H8N2O2 | 100mg

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2-(2-Pyrimidinyl)benzoic acid is a drug intermediate for synthesis of various active compounds

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Frontier Specialty Chemicals 1G 5-(CHLOROMETHYL)-1,3-DIMETH

5-(Chloromethyl)-1,3-dimethyl-1H-pyrazole; CAS: 852227-86-2; 1g

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Medchemexpress LLC DIM-C-pPhOCH3 | 33985-68-1 | 99.4% | 352.43 | 1 ML

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DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor. This product is for research use only.

• Decreases survival and induces apoptosis in RKO colon cancer cells, accompanied by induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein.
• Induces Nur77-independent apoptosis.
• Inhibits cell growth after treatment for 24, 48, or 72 h, with maximum inhibitory response observed after 72 h, leading to considerable cell detachment and dead cells.
• Growth-inhibitory effects after 72 h are accompanied by markers of apoptosis, including PARP cleavage and cleavage of caspase-3, caspase-9, and caspase-8.
• Inhibits tumor growth in athymic nude mice bearing RKO cell xenografts.
• Significantly decreases tumor volumes and final tumor weights compared with corn oil controls in athymic nude mice bearing RKO cell xenografts.

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eMolecules​ 885519-32-4 | 6-CHLORO-1H-INDAZOL-4-AMINE | AstaTech | MFCD07781370 | 167.600 | C7H6ClN3 | 95.000 | Nc1cc(Cl)cc2[nH]ncc12 | 1g | 412394803

6-CHLORO-1H-INDAZOL-4-AMINE | AstaTech | 885519-32-4 | MFCD07781370 | 167.600 | C7H6ClN3 | 95.000 | Nc1cc(Cl)cc2[nH]ncc12 | 1g | 412394803

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