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Filtered Search Results
Medchemexpress LLC TH-Z93 | 2260887-09-8 | C12H22N2O7P2 | 25 MG
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TH-Z93 is a lipophilic bisphosphonate and an FPPS inhibitor with an IC50 of 90 nM. It has shown strong prophylactic effects in a pathogenic influenza model and inhibited tumor growth in a B16-OVA cells xenograft mice model, making it suitable for various research applications.
- Lipophilic bisphosphonate
- FPPS inhibitor (IC50: 90 nM)
- Shows strong prophylactic effects in pathogenic influenza model
- Inhibits tumor growth in B16-OVA cells xenograft mice model
- High purity (98.41%)
- Available in various package sizes
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Medchemexpress LLC TH-Z93 | 2260887-09-8 | C12H22N2O7P2 | 50 MG
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TH-Z93 is a lipophilic bisphosphonate that functions as a potent FPPS inhibitor with an IC50 of 90 nM. This compound is suitable for various research applications requiring FPPS inhibition.
- Potent FPPS inhibitor (IC50: 90 nM)
- Lipophilic bisphosphonate
- Molecular weight: 368.26
- Appearance: White to off-white solid
- Purity: 98.41%
- Long-term powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in water: 7.81 mg/mL (21.21 mM)
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Medchemexpress LLC TH-Z145 | 2260887-57-6 | C16H28O7P2 | 1 ML
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TH-Z145 is a lipophilic bisphosphonate and an FPPS inhibitor with an IC50 of 210 nM. It has shown strong prophylactic effects in a pathogenic influenza model and inhibits tumor growth, prolonging survival in a B16-OVA cells xenograft mice model. It is intended for research use only.
- Lipophilic bisphosphonate and FPPS inhibitor
- IC50 of 210 nM
- Strong prophylactic effects in pathogenic influenza model
- Inhibits tumor growth and prolongs survival in B16-OVA cells xenograft mice model
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Medchemexpress LLC KN-93 hydrochloride | 1956426-56-4 | C26H30Cl2N2O4S | 25 MG
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KN-93 hydrochloride is a cell-permeable, reversible, and competitive inhibitor of calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM. It is intended for research use only.
- Cell-permeable, reversible, and competitive CaMKII inhibitor
- Ki of 370 nM
- Arrests cells in G1 phase
- Blocks cell growth stimulated by basic fibroblast growth factor, platelet-derived growth factor-BB, and epidermal growth factor
- Inhibits H+, K+-ATPase activity
- Prevents increased LV developed pressure during action potential prolongation
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Medchemexpress LLC TH-Z145 | 2260887-57-6 | C16H28O7P2 | 25 MG
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TH-Z145 is a lipophilic bisphosphonate that functions as an FPPS inhibitor with an IC50 of 210 nM. It has shown promising effects in preclinical studies, including strong prophylactic effects in pathogenic influenza models and inhibition of tumor growth in xenograft mouse models.
- Exhibits strong prophylactic effects in pathogenic influenza models
- Inhibits tumor growth and prolongs survival in B16-OVA xenograft mouse models
- Functions as an FPPS inhibitor with an IC50 of 210 nM
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL
- Not classified as a hazardous substance or mixture
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC YL-109 | 36341-25-0 | 99.26% | 257.31 | 25 MG
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YL-109 is an antitumor agent that induces carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. It inhibits breast cancer cell growth and invasiveness.
- Inhibits cell proliferation, motility, and invasiveness in breast cancer cells.
- Increases both CHIP mRNA and protein levels in MDA-MB-231 cells.
- Inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo.
- Store powder at -20°C for 3 years, 4°C for 2 years.
- Store in solvent at -80°C for 2 years, -20°C for 1 year.
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Medchemexpress LLC (2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone | 141627-42-1 | 99.6% | C20H19NO5 | 50 G
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone is a chemical compound functioning as a drug intermediate for the synthesis of various active compounds. It is designated for research use only.
- Functions as a drug intermediate for active compound synthesis
- Intended for research use only
- High purity of 99.6%
- Appears as a solid
- Color ranges from yellow to brown
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Medchemexpress LLC 2,4-Dimethylthiazole-5-carboxylic acid | 53137-27-2 | 157.19 | 100 MG
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2,4-Dimethylthiazole-5-carboxylic acid is a building block utilized in chemical synthesis. It is intended for research use only.
- Solid appearance
- White to off-white color
- Molecular formula: C6H7NO2S
- CAS number: 53137-27-2
- Building block for chemical synthesis
- For research use only
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eMolecules Pharmablock tert-butyl 3 9-diazaspiro[5 5]undecane-3-carboxylate 250mg 551129010 PBN2011395 0 000 173405-78-2 MFCD05861627 254 374 C14H26N2O2
Pharmablock tert-butyl 3 9-diazaspiro[5 5]undecane-3-carboxylate 250mg 551129010 PBN2011395 0 000 173405-78-2 MFCD05861627 254 374 C14H26N2O2
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eMolecules Pharmablock 3-(tert-butoxycarbonylamino)bicyclo[1 1 1]pentane-1-carboxylic acid 250mg 551080605 PB06488 0 000 303752-38-7 MFCD09971715 227 260 C11H17NO4
Pharmablock 3-(tert-butoxycarbonylamino)bicyclo[1 1 1]pentane-1-carboxylic acid 250mg 551080605 PB06488 0 000 303752-38-7 MFCD09971715 227 260 C11H17NO4
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Medchemexpress LLC Solvent Yellow 93 (C.I. 48160) | 4702-90-3 | 99.1% | 5 MG
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Solvent Yellow 93 is an azomethine dye primarily used as a colorant in various applications.
- Used as a colorant for toner.
- Used for coloring polyester fiber pulp.
- Used to make polyester masterbatch.
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Medchemexpress LLC S2-16 | 672333-56-1 | 97.4% | 2973.36 | 5 MG
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S2-16 is a synthetic peptide derived from the S2 region of cardiac myosin. It functions as a cryptic epitope, meaning it's not typically recognized by antibodies or T cells when the animal is immunized with the intact antigen. S2-16 has been shown to induce myocarditis in Lewis rats and can be utilized to study the mechanism of autoimmune myocarditis.
- For research use only
- Not sold to patients
- Purity: 97.41%
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![Medchemexpress LLC [Sar9,Met(O2)11]-Substance P | 110880-55-2 | 99.6% | 1393.66 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000424719.png-250.jpg)
Medchemexpress LLC [Sar9,Met(O2)11]-Substance P | 110880-55-2 | 99.6% | 1393.66 | 5 MG
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[Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
- High purity: 99.6%
- Appearance: White to off-white solid
- Molecular weight: 1393.66
- Soluble in H2O and PBS at 100 mg/mL with sonication
- Powder stability: 2 years at -80°C, 1 year at -20°C (sealed, away from moisture)
- In-solvent stability: 6 months at -80°C, 1 month at -20°C (sealed, away from moisture)
- Targets NK1 receptor with an IC50 of 1.1 x 10-10 M in human U373MG cells
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Medchemexpress LLC VH-298 | 2097381-85-4 | MFCD30742947 | >98.0% | 523.6 g/mol | C27H33N5O4S | 100 MG
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VH-298 is a cell-permeant, small-molecule inhibitor of the von Hippel-Lindau (VHL) : hypoxia-inducible factor alpha (HIF-α) protein-protein interaction. It stabilizes HIF-α in cells by blocking VHL recognition and is used in biochemical and cellular research, including as an E3 ligase ligand in targeted protein degradation studies.
- Inhibits the VHL:HIF-α protein-protein interaction (Kd ≈ 80-90 nM).
- Stabilizes HIF-α in cells for hypoxia-response and signaling studies.
- Useful as an E3 ligase ligand in PROTAC design and targeted degradation research.
- Cell-permeant small molecule suitable for cellular assays.
- Reported purity ≥98% (HPLC); molecular weight 523.6 g/mol.
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Medchemexpress LLC Phospho-Met c-Met (Tyr1349) antibody (YA213) | 100 UL
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The Phospho-Met c-Met (Tyr1349) antibody (YA213) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Phospho-Met c-Met (Tyr1349). This antibody is affinity purified and supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA with 0.01% Sodium azide as a preservative.
- Recognizes Phospho-Met c-Met (Tyr1349)
- Host species: Rabbit
- Reactivity: Human
- Research field: Signal transduction
- Applications: Western blot (1:500-1:1000) and immunoprecipitation (1:20)
- Molecular weight: Predicted 156 kDa, observed 170/140 kDa
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
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