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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (32,318)
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Keyword Search:
1 – 15 of 30,648 results
1

Thermo Scientific™ ProPac™ WCX-10 HPLC Columns
GSA_VA GREENER_CHOICE

Separate proteins and their variants using these weak cation-exchange columns with exceptionally high resolution.

EDGE
Pore Size Nonporous
Particle Size 10 μm
Stationary Phase Carboxylate
Temperature 60°C
Phase Ion Exchange
Column Type Ion Exchange
pH 2 to 12
Quantity Each
Product Line ProPac
2

Thermo Scientific™ Accucore™ C18 HPLC Columns
GSA_VA

Use this column, with its specially designed solid core, for a broad range of nonpolar analytes across multiple applications.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 9%
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 1 to 11
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
USP Type L1
3

Thermo Scientific™ MAbPac™ Reversed Phase HPLC Columns
GREENER_CHOICE

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins.

EDGE
Pore Size 1500 Å
Particle Size 4 μm
Phase Reversed Phase
Max. Pressure 4000 psi (275 bar)
4

Thermo Scientific™ DNAPac™ RP Columns
GREENER_CHOICE

Get high resolution LC and LC-MS separation of oligonucleotides, including double-stranded (ds) DNA/RNA fragments, using these DNAPac reversed phase columns.

EDGE
5

Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns
GSA_VA

Use these endcapped, ultrapure, silica-based columns to generate exceptional peak shape and resolution for HPLC and LC/MS analyses using generic gradients

6

Thermo Scientific™ Hypersil™ Silica HPLC Columns

Use the efficient and selective Thermo Scientific™ Hypersil™ Silica LC Columns for normal phase chromatography of nonpolar and moderately polar organic compounds.

Pore Size 120 Å
Stationary Phase Silica
Temperature 60°C
Phase Normal Phase
Column Type Normal Phase
pH 2 to 8
Surface Area 170 m²/g
USP Type L3
7

Thermo Scientific™ Hypersil GOLD™ SAX HPLC Columns

Analyze smaller organic molecules, including nucleotides and organic acids, quickly and efficiently with Thermo Scientific™ Hypersil™ GOLD SAX LC Columns.

Pore Size 175 Å
Carbon Load 2.5%
Stationary Phase Quaternary Amine
Temperature 60°C
Phase Ion Exchange
Column Type Ion Exchange
pH 2 to 8
Surface Area 220 m²/g
USP Type L14
8

Thermo Scientific™ Syncronis™ C18 HPLC Columns

Robust separations with highly pure, high surface area silica that is double endcapped Syncronis C18 preparative HPLC columns with inertness toward basic compounds.

Pore Size 100 Å
Particle Size 5 μm
Carbon Load 16%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous, Ultrapure Silica
Column Type Reversed Phase
pH 2 to 9
Surface Area 320 m²/g
USP Type L1
9

Thermo Scientific™ Hypersil GOLD™ PREP C18 HPLC Columns

Easily scale up your method to prep LC using Hypersil GOLD C18 preparative HPLC columns for excellent peak shape in a variety of formats including XtendedLife technology.

Pore Size 175 Å
Carbon Load 10%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous, Ultrapure Silica
Column Type Reversed Phase
pH 2 to 9
Surface Area 220 m²/g
USP Type L1
10

Thermo Scientific™ BioBasic™ SCX HPLC Columns

BioBasic SCX LC Columns are optimized for the separation of proteins, peptides and other cationic species.

Pore Size 300 Å
Particle Size 5 μm
Carbon Load 3%
Stationary Phase Sulfonic Acid
Temperature 60°C
Phase Ion Exchange
Endcapped No
Column Type Ion Exchange
pH 2 to 8
Surface Area 100 m²/g
Max. Pressure 5800 psi (400 bar)
Product Line BioBasic
USP Type L52
11

Restek™ Ultra Aqueous HPLC Prep Columns with C18 Packing, 5um Particle Size
SDP

Easy scale-up from Restek analytical columns.

Pore Size 100 Å
Stationary Phase aQ C18
Temperature 80°C
Phase Reversed Phase
Endcapped No
Column Type Reversed Phase
Column Chemistry Octadecyl Silane chemically bonded to porous Silica or Ceramic microparticles
Hydrophobicity No
Surface Area 300 m²/g
Functionality/Interaction Type Dispersive interaction
Column Format Preparative Column
Particle Size 5 μm
Ligand Type Proprietary polar modified and functionally bonded C18
Type Preparative Column
Carbon Load 2 to 20%
Packing Material Silica
pH 2.5 to 8
Polarity Polar
Technique Reverse Phase HPLC
Particle Shape Spherical
Film Thickness 5 μm
USP Type L1
12

Thermo Scientific™ Aquasil™ 3μm C18 HPLC Columns

Available in limited dimensions. Please contact Customer Service for more details.

Pore Size 100 Å
Particle Size 3 μm
Carbon Load 12%
Stationary Phase C18
Phase Reversed Phase
For Use With LC/MS
Endcapped Yes
Packing Material Silica
Column Type Reversed Phase
pH 2 to 8
Surface Area 310 m²/g
USP Type L1
Column Format Analytical Column
13

Thermo Scientific™ Hypersil GOLD™ aQ C18 Polar Endcapped HPLC Columns
GSA_VA

Retain and resolve polar analytes with highly aqueous mobile phases.

Pore Size 175 Å
Carbon Load 12%
Temperature 60°C
Phase Reversed Phase
Endcapped Polar
Column Type Reversed Phase
pH 2 to 9
Surface Area 220 m²/g
USP Type L1
14

MilliporeSigma™ SeQuant™ ZIC™-HILIC Analytical PEEK Columns
GSA_VA

PEEK coated HPLC column

Quantity 1/Pk.
Material Metal-free PEEK
15

Thermo Scientific™ Hypersil™ PREP ODS C18 HPLC Columns

Perfect for routine workflows, our Hypersil PREP ODS preparative LC column is a general purpose C18 used in a broad range of USP L1 applications.

Pore Size 130 Å
Carbon Load 10%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous Silica
Column Type Reversed Phase
pH 2 to 8
Surface Area 195 m²/g
USP Type L1