HPLC Guard Columns and Cartridges
YMC America, Inc HS C18 grd 120A 5um 10x2.1mm
Hydrosphere C18 is based on highly inert ultra-pure pH neutral silica and is designed to maintain a hydrophilic surface for superior separation of hydrophilic compounds Minimal metal content and very low concentrations of residual silanols make this an ideal phase for the analysis of basic pharmaceuticals and chelating compounds even under LC-MS conditions such as separation in non-phosphate buffered systems In addition the ability to separate polar compounds under highly aqueous mobile phase conditions without loss in retention plate counts and peak performance greatly enhances the versatility of Hydrosphere C18
Waters Corp Waters SunFire C18 Prep Guard Cartridge, 5 μm, 100 Å, 19 mm × 10 mm
This SunFire C18 Prep Guard Cartridge is a single piece of lab equipment for general purpose method development at low pH. Its C18 ligand is highly retentive for basic compounds. It protects columns by removing particle pollution, extending their lifetime and ensuring compatibility with UPLC columns for reversed-phase Liquid Chromatography.
- Extends prep column life, preserves analytical performance.
- Longer column lifetime, lower purification expenses.
- Protects C18 columns, extends lab equipment life by removing particle pollution.
- Protects 19 mm I.D. C18 columns with 5 μm sorbent particles.
- Tolerates high pressures in UPLC system applications.
- Delivers optimal performance across a wide operating pH range.
- Includes patented BEH Technology C18, 100Å, 5μm particles.
- Q.C. tested to ensure consistent performance, longer analytical column life.
Waters Corp WATERS CORPORATION Sentry Guard Cartridge, C18, 5 μm, 4.6 mm, 20 mm
XSelect CSH C18 columns function as general-purpose columns, offering alternative selectivity compared to other C18 sorbents. The Charged Surface Hybrid (CSH) technology addresses common column-related issues such as peak shape asymmetry, poor loading for basic compounds, column bleed, and slow mobile-phase re-equilibration.
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Hybrid
- Minimum pH range: 1
- Maximum pH range: 11
- Maximum pressure: 6000 psi (415 bar)
- Endcapped: Yes
- Silanol activity: Low
- Particle shape: Spherical
- Particle size: 5 μm
- Pore size: 130 Å
- Format: Sentry guard cartridge
- Surface area: 185
- System: HPLC
- Particle technology: CSH
- USP classification: L1
- Inner diameter: 4.6 mm
- Length: 20 mm
- Carbon load: 15%
- Units per package: 2 pk
Waters Corp XSelect Prep Guard Cartridge, 130Å, 5 μm, 19 mm × 10 mm
The XSelect CSH Fluoro-Phenyl Prep Guard Cartridge maximizes selectivity differences for method development, especially with low pH mobile phases. Its non-encapped sorbent enhances retention of acidic compounds and protects prep columns from impurities.
- Maximizes selectivity differences for method development, particularly with low pH mobile phases.
- Non-encapped sorbent enhances retention of acidic compounds.
- High-performance guardrail shields prep columns from impurities and contaminants.
- Preserves lab equipment and samples.
- Compatible with Acquity UPLC Systems.
- Advanced 130Å, 5μm sorbent bed for efficient particulate capture.
- Bonded hybrid silica substrate ensures durability and high-performance.
- Extends the lifetime of prep columns.
Waters Corporation VanGuard Pre-column, BEH Amide, 1.7 μm
This VanGuard pre-column utilizes BEH technology with a chemically stable, trifunctionally bonded amide phase, allowing for the retention and separation of extremely polar compounds across a wide pH range (2 to 12). It connects directly to the UPLC column inlet, minimizing extra column volumes and leaks.
- Protects column from contamination.
- Reduces peak tailing and improves resolution.
- Extends analytical column lifetime.
- Retains polar analytes poorly retained by reversed-phase chromatography.
- Facilitates mobile phase use from pH 2–11.
- Increases chemical stability for high pH and temperature applications.
- Prevents Schiff base formation, enhancing quantitation.
- Increases mass spectrometry response, simplifying sample pre-treatment.
- Enables high resolution and high-speed analysis with 1.7 μm particle size.
Waters Corp Atlantis dC18 Sentry Guard Cartridge, 100Å, 3 µm, 4.6 mm X 20 mm, 2/pk
Atlantis dC18 columns are universal, silica-based, reversed-phase C18 columns that are used for polar compound retention. The Atlantis dC18 columns feature di-functionally bonded C18 ligands that have been optimized for use with highly aqueous mobile phases, including 100% water.
Waters Corp Waters Spherisorb Guard Cartridge, C1, 5 μm, 80 Å, 4.6 mm ID
Spherisorb C1 columns are classified as USP L13 and are general purpose columns that contain trimethylsilane bonded to silica.
- C1 chemistry
- Reversed phase separation mode
- Silica particle substrate
- pH range of 2 to 8
- Maximum pressure of 6000 psi (415 Bar)
- Spherical particle shape
- 5 μm particle size
- 80 Å pore size
- Guard cartridge format
- Designed for HPLC systems
- 4.6 mm inner diameter
- 30 mm length
- 2% carbon load
- Comes in a package of 3 units
Waters Corp µBondapak C18 Radial-Pak Column, 125Å, 10 µm, 8 mm X 100 mm, 1/pk
µBondapak C18 columns are general purpose, silica-based, reversed-phase C18 columns that are based on 10 µm particle technology. As a starting point for preparative chromatography, no other column can provide the balance between resolution, throughput and cost.
Waters Corp Waters Styragel GPC Guard Column, 20 μm, 4.6 mm, 30 mm, DMF
Styragel Guard columns increase the lifetime of 7.8 mm or 4.6 mm ID columns. This GPC Guard Column protects GPC Columns in reversed-phase Liquid Chromatography by filtering chemical and particulate impurities from the mobile phase stream, enhancing analytical performance.
- Manufactured under cGMP, ISO 9001 conditions, ensuring optimal performance, selectivity, sensitivity, and speed of analysis.
- Testing results meet high standards and narrow specification ranges for excellent, reproducible performance.
- Produced using premier materials, enhancing the GPC columns\' performance and longevity.
- Removes contaminants, maintaining UPLC, UHPLC, and HPLC separation efficiency.
Waters Corp Waters Guard Cartridge, C18, 10 μm, 3.9 mm X 20 mm
- Designed to be used with C18 columns.
- Protects analytical columns from damaging contaminants.
- Enhances and improves column analytical performance.
- Extends the lifetime of analytical columns.
- Maintains UPLC, UHPLC, and HPLC separation efficiency.
- Manufactured under cGMP, ISO 9001 conditions.
- Each unit is tested and certified for use.
- Tolerates pressures up to 6000 psi (415 bar).
- Made using identical packing materials as analytical columns.
- Features BEH Technology C18.
Waters Corp Waters UPLC Glycan VanGuard Pre-column, BEH Amide, 1.7 μm
The BEH Glycan Separation Technology Column is optimized for UPLC systems with fluorescence detection, separating released glycans from biopharmaceuticals as 2-aminobenzamide derivatives. This VanGuard pre-column directly connects to the analytical column's inlet, minimizing extra column volumes and leaks. It safeguards the analytical column from contaminants, enhancing performance by filtering impurities.
- Chemistry: Amide
- Separation mode: Hydrophilic interaction (HILIC)
- Particle substrate: Hybrid
- pH range: 2 to 11 pH
- Maximum pressure: 18,000 psi (1240 Bar)
- Particle size: 1.7 μm
- Pore size: 130 Å
- Endfitting type: Direct-Connect
- Format: VanGuard Pre-column
- System compatibility: UPLC, UHPLC
- Inner diameter: 2.1 mm
- Length: 5 mm
- Molecular weight range: 1,000 to 150,000
- Manufactured under cGMP, ISO 9001 conditions.
Sepax Technologies Inc Sepax HPLC Column Proteomix WCX, NP10, 4 x 10 mm
Proteomix ion-exchange phases have been innovatively developed for achieving high ion-exchange capacity, a breakthrough technology for non-porous resins. Proteomix packing support is composed of a rigid, spherical, highly cross-linked poly(styrene divinylbenzene) (PS/DVB) non-porous bead with particle size selections of 1.7, 3, 5 and 10 µm. The PS/DVB resin surface is grafted with a highly hydrophilic, neutral polymer thin layer with the thickness in the range of nanometer. The hydrophobic PS/DVB resin surface is totally covered by a hydrophilic coating that eliminates non-specific bindings with biological analytes, leading to high efficiency and high recovery separations for biological molecules.
Sepax Technologies Inc Sepax HPLC Column Proteomix SAX, NP5, Guard cartridge with holder, 4 x 10 mm
Proteomix ion-exchange phases have been innovatively developed for achieving high ion-exchange capacity, a breakthrough technology for non-porous resins. Proteomix packing support is composed of a rigid, spherical, highly cross-linked poly(styrene divinylbenzene) (PS/DVB) non-porous bead with particle size selections of 1.7, 3, 5 and 10 µm. The PS/DVB resin surface is grafted with a highly hydrophilic, neutral polymer thin layer with the thickness in the range of nanometer. The hydrophobic PS/DVB resin surface is totally covered by a hydrophilic coating that eliminates non-specific bindings with biological analytes, leading to high efficiency and high recovery separations for biological molecules.
Sepax Technologies Inc Sepax HPLC Column Bio-C18, 5 µm, 200 Å, 4 x 10 mm
Wide range of pore sizes and high compatibility with 100% aqueous phases make Bio-C18 columns ideal for high resolution mapping of peptides and separation of natural and synthetic peptides and small proteins. The specially designed surface bonding chemistry and the pore sizes allow for extended retention and selectivity for polar and hydrophilic compounds, such as peptides and amino acids. C18 monolayer formed by special bonding chemistry does not collapse in pure aqueous solution.