General Western Blot Reagents
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Filtered Search Results
Abcam Ingenol-3-angelate, PKC activator, 5MG
MW 430.5 Da, Purity >98%. Selective activator of PKC isoforms, like PKCθ in T cells. Achieve your results faster with highly validated, pure and trusted compounds.
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Abcam Methyl 3-hydro x yhe x anoate, 3-Hydro x y fatty acid methyl ester, 25MG
MW 146.18 Da, Purity >98%. 3-Hydroxy fatty acid methyl ester. For use as standard in methanolysis assay and in biological systems. See similar products
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Abcam Asta x anthin, Antio x idant agent, 5MG
MW 596.8 Da, Purity >97%. Potent antioxidant agent. PPARα agonist and PPARγ antagonist. Free radical scavenger. Reduces oxidative stress. Induces apoptosis. Inhibits NF-κB. Shows anti-inflammatory, antihypertensive, cardioprotective, neuroprotective and antitumor effects in vivo. Orally active.
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Abcam ACTH (1-24) (human), ACTH/MC2 receptor agonist, 1MG
MW 2933.4 Da. ACTH (1-24) (human), ACTH/MC2 receptor agonist. Achieve your results faster with highly validated, pure and trusted compounds.
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Abcam C6 Ceramide, biologically active ceramide analog, 5MG
MW 397.6 Da, Purity >98%. Non-physiological and biologically active ceramide analog. Various pharmacological activities including activation of protein phosphatase 2A and MAPK, suppression of insulin-induced tyrosine phosphorylation and induction of cell cycle arrest at the G0/G1 transition. Active in vivo and in vitro.
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Abcam N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide hydrochloride, condensing reagent, 10G
MW 191.7 g/mol. Water-soluble condensing reagent. Generally utilized as a carboxyl activating agent for amide bonding with primary amines. Additionally, it reacts with phosphate groups. Utilized in peptide synthesis, crosslinking proteins to nucleic acids as well as preparation of immunoconjugates.
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Abcam (±)-1,2-Didecanoylglycerol (10:0), Protein kinase C activator, 50MG
MW 400.6 g/mol, Purity >98%. Non-physiologic diacylglycerol (DAG). Cell-permeable protein kinase C activator in platelets. Enhances anterior pituitary hormone secretion in vitro.
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Abcam AS601245, JNK inhibitor, 25MG
MW 372.4 Da, Purity >95%. Potent, selective, ATP competitive JNK inhibitor (IC₅₀ values are 150, 220 and 70 nM for hJNK1,2 and 3 respectively). Reduces cell adhesion and migration in cancer cells. Shows neuroprotective, anti-ischemic effects in vivo. Blood-brain barrier and cell-permeable.
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Abcam AICAR (Acadesine/AICA riboside) (aqueous solution), protein kinase activator, 50MG-LQD
MW 258.23 Da, Purity >98%. Cell-permeable activator of AMP-activated protein kinase. Is taken up into cells by adenosine transporters and phosphorylated by adenosine kinase to the active nucleotide ZMP (5-aminoimidazole-4-carboxamide ribonucleoside), which mimics effects of AMP on the AMPK system. Active in vivo and in vitro.
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Abcam G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent, 1G
MW 692.7 Da. Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo. .
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Abcam Rhod-2 AM, fluorescent Ca2+ indicator, 1MG
Rhod-2 AM, a fluorescent Ca2+ indicator is cell-permeable. Binds to Ca2+ (Kd = 570 nM) and fluoresces yellow/orange upon Ca2+ binding. - Cited in over 20 publications - Purity > 93% - Soluble in DMSO to 1 mg/ml - Excitation/Emission: Ex: 552nm, Em: 581nm
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Abcam Docosa-4Z,7Z,10Z,13Z,16Z,19Z-he x aenoic acid, Anti-inflammatory agent, 100MG
MW 328.5 g/mol, Purity >98%. Abundant essential n-3 polyunsaturated fatty acid in the CNS, shown to play a major anti-inflammatory role. Prevents LPS-induced dendritic cell maturation, characterized by a lack of proinflammatory cytokine production. Improves the nitroso-redox balance and reduces VEGF-mediated angiogenic signaling in microvascular endothelial cells. Inhibits Aβ1-42 fibrillation and toxicity in vitro. Retinoid X receptor (RXR) ligand.
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Abcam VAS 2870, NADPH o x idase inhibitor, 10MG
MW 360.4 g/mol, Purity >98%. NADPH oxidase inhibitor. Blocks PDGF-mediated NADPH activation and ROS production. Inhibits PMS-induced oxidative burst (IC₅₀ = 2 μM, HeLa cells). Shows anti-ischemic effects ex vivo. .
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Abcam Quinol 1h, Antitumor agent, 25MG
MW 365.4 Da, Purity >99%. Potent, selective antitumor agent. Antitumor activity observed in HCT 116 (GI₅₀ = 40 nM) and HT 29 (GI₅₀ = 380 nM), and in breast cancer cell lines. Potent inhibitory effect in NCI 60 cells (GI₅₀ =16 nM and LC₅₀ = 2.24 μM). Active in vitro.
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Abcam MDL 72222, 5-HT3 receptor antagonist, 50MG
MW 314.21 g/mol, Purity >99%. Selective 5-HT₃ receptor antagonist. Shows antiemetic effects in vivo. Suppresses voluntary ethanol consumption that is mediated by 5-HT₃ receptor in rats.
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