ELISA Substrates and Reagents
ABclonal Technology Phospho-SHP2-Y542 Rabbit pAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
ABclonal Technology Phospho-Beclin 1-Ser90 Rabbit pAb
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Genscript Corporation CEACAM-6/CD66c His Cynomolgu
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role in carcinogenesis and development
Cayman Chemical p38α MAPK-IN-1, Purity: ≥98%, CAS: 443913-15-3, 5 mg
A p38α MAPK inhibitor (IC50 = 5,500 nM in an HTRF assay); inhibits LPS-induced TNF-α production in THP-1 cells (EC50 = 6,200 nM); has been used in the study of p38α MAPK inhibitor binding interactions and kinetics
Medchemexpress LLC Phospho-AKT(S473) Antibody (YA5759) | 56 kDa | 100 UL
Phospho-AKT(S473) Antibody (YA5759) is a mouse-derived, non-conjugated monoclonal antibody targeting Phospho-AKT(S473). AKT protein is crucial in regulating cellular processes like metabolism, proliferation, cell survival, growth, and angiogenesis, functioning through serine and/or threonine phosphorylation of numerous downstream substrates.
- Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
- Stored at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Shipping with blue ice
- Suitable for WB, IHC-P, and ICC/IF applications
ABclonal Technology DDR2 Rabbit pAb
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
Miltenyi Biotec, Inc. aGARP (LRRC32)-VioBright 515, m, 100 t
Identification and enumeration of GARP (LRRC32)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Medchemexpress LLC Fetuin A (human), recombinant, expressed in HEK293 cells | 9014-81-7 | >95.0% | 500UG
Recombinant human Fetuin A (AHSG) produced in HEK293 cells with a C-terminal His tag. Supplied as a lyophilized powder formulated in 20 mM PB, 150 mM NaCl, pH 7.4, the product is intended for research applications requiring a high-purity serum glycoprotein involved in mineralization and cellular processes.
- Recombinant human protein expressed in HEK293 cells.
- C-terminal His tag for purification and detection.
- High purity (>95% by reducing SDS-PAGE).
- Approximate molecular weight ~60.0 kDa (349 aa, A19-V367).
- Lyophilized formulation in 20 mM PB, 150 mM NaCl, pH 7.4.
- Recommended storage at -20°C; aliquot and freeze at -80°C for long-term storage.
- Reported biological activity: inhibits calcium phosphate precipitation (IC50 46.163 μg/mL).