ELISA Substrates and Reagents
Cayman Chemical para-fluoro Phenthyl 4-nPP 5mg
An analytical reference standard that is structurally similar to known opioids; intended for research and forensic applications
Selleck Chemical LLC Coelenterazine 1mg 55779-48-1
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Revvity Health Sciences Inc LANCE Ultra Lysis Buffer 2 (10X), 100 mL
LANCE Ultra Lysis Buffer 2 (10X), 100 mL
Biolegend TMB High Sensitivity Substrate Solution
TMB High Sensitivity Substrate Solution Apps: ELISA; Size: 60 mL
Cell Signaling Technology PathScanR Phospho-c-Kit Tyr703 Sandwich ELISA Kit 50 Kit
PathScanR Phospho-c-Kit Tyr703 Sandwich ELISA Kit 50 Kit
ABclonal Technology Phospho-PPP1R12A-S668 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a subunit of myosin phosphatase, which regulates the actin-myosin interaction downstream of the GTPase Rho. RhoA, in its active GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, affecting smooth muscle contraction and nonmuscle cell function. RhoA activates Rho-kinase, which phosphorylates MBS and inactivates myosin phosphatase. Overexpression or activation of RhoA increases MBS and MLC phosphorylation. This pathway regulates the balance of actin and myosin interaction. Several isoforms of this gene have been identified due to alternative splicing.
Genscript Corporation CEACAM-5/CD66eBiotin His
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
Cell Signaling Technology PathScanR Phospho-HSP27 Ser82 Sandwich ELISA Kit 50 Kit
PathScanR Phospho-HSP27 Ser82 Sandwich ELISA Kit 50 Kit
ABclonal Technology Phospho-NEDD4L-S448 Rabbit pAb
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ABclonal Technology Phospho-ERK1-Y204 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
ABclonal Technology Phospho-HSP27/HSPB1-S78 Rabbit pAb
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Cayman Chemical p38a MAPK-IN-1 50mg
A p38α MAPK inhibitor (IC50 = 5,500 nM in an HTRF assay); inhibits LPS-induced TNF-α production in THP-1 cells (EC50 = 6,200 nM); has been used in the study of p38α MAPK inhibitor binding interactions and kinetics