Protein Molecular Weight Markers
ABclonal Technology KANK2 Rabbit pAb
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.
ABclonal Technology IBSP Rabbit pAb
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
ABclonal Technology METTL21C Rabbit pAb
Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in protein methylation. Located in nucleus. Part of protein-containing complex.
ABclonal Technology FKBP1B Rabbit pAb
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
ABclonal Technology PPP6C Rabbit mAb
This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.
ABclonal Technology CLNS1A Rabbit pAb
This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology HNRPLL Rabbit pAb
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC, MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).
ABclonal Technology NDRG3 Rabbit pAb
Predicted to be involved in signal transduction. Located in cytoplasm.
Immunology Consultants 12 Epitope Tag Control, 0.2 ml
This protein solution contains a 41kDa alpha tubulin fragement with 12 commonly used epitope tags that is intended for use as a positive control in Western Blot assays.GST – T7 – HSV – C-MYC – VSV – Glu-Glu – V5 – E-tag – DYKDDDDK (Sigma Flag) – S-tag – HA - 6xHIS.
Cayman Chemical PI-103hydrochlorIde 10mg
A potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50 = 2, 8, 20, 26, 48, 83, 88, and 150 nM for DNA-PK, p110α, mTORC1, PI3-KC2β, p110δ, mTORC2, p110β, and p110γ, respectively)
ABclonal Technology ELL Rabbit pAb
Enables phosphatase binding activity. Involved in positive regulation of transcription, DNA-templated and snRNA transcription. Located in cytosol, nuclear body, and transcriptionally active chromatin. Part of transcription elongation factor complex.
ABclonal Technology UTP18 Rabbit pAb
Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in nuclear membrane, nucleolus, and nucleoplasm.
ABclonal Technology TET2 Rabbit pAb
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
ABclonal Technology ENPP5 Rabbit mAb
This gene encodes a type-I transmembrane glycoprotein. Studies in rat suggest the encoded protein may play a role in neuronal cell communications. Alternatively spliced transcript variants have been described.