Protein Molecular Weight Markers
ABclonal Technology FBXO42 Rabbit pAb
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A, MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
ABclonal Technology IL17RA Rabbit pAb
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Cayman Chemical VItelogenIncod PolycLNal 500uL
Isoprostanesprostaglandin PG-like productsof freeradicalinducedlipidperoxidation.{320 Although the isoprostanes derived from arachidonic acid are the best characterized many other polyunsaturated fatty acids can form isoprostanes.{7323} (±)5-iPF2a-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date the most extensively studied of these is 8-isoprostane (8-epi-PGF2a iPF2a-III).{30645011} However 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress.{8367} (±)5-iPF2a-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane Type VI isoprostanes form internal lactones which facilitates their extraction purification fro biological samples8367940869106390
Biotang Inc Prestained Protein Marker (10-240 Kda),Three color bands(Green, Blue, Red). Ready-to-Use no need to boil.Broad range size estimation(11-240kDa). Highly purified and blended 11 recombinant proteins 2x250ul. Store at 2-8 deg.C
Prestained Protein Marker (10-240 Kda),Three color bands(Green, Blue, Red). Ready-to-Use no need to boil.Broad range size estimation(11-240kDa). Highly purified and blended 11 recombinant proteins 2x250ul. Store at 2-8 deg.C
![ABclonal Technology [KO Validated] PRKAR1A Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000138662.jpg-250.jpg)
ABclonal Technology [KO Validated] PRKAR1A Rabbit pAb
cAMP is a signaling molecule that activates cAMP-dependent protein kinase, which transduces signals through phosphorylation of target proteins. The inactive kinase is a tetramer of two regulatory and two catalytic subunits. cAMP dissociates this holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free catalytic subunits. This gene encodes one of the regulatory subunits and was found to down-regulate liver gene expression in hepatoma-fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). The gene can fuse with the RET protooncogene to form the PTC2 chimeric oncogene in thyroid tumors. A nonconventional nuclear localization sequence suggests its role in DNA replication by transporting the RFC40 subunit. Several splice variants encoding different isoforms have been observed.
Biolegend Purified anti-mouse Podoplanin
Purified anti-mouse Podoplanin Recombinant [QA20A17]; Isotype: Rat IgG1, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
Hach Company 5500sc Standard 2 Low-Range Phosphate standard solution, 2 L - for 5500sc low-range phosphate analyzer
Standard 2 low-range phosphate calibration solution in a 2 L bottle for use with the Hach 5500sc low-range phosphate analyzer. Use this certified standard to perform calibration and routine accuracy checks to help ensure reliable phosphate measurements.
- Provides a low-range phosphate calibration standard for analyzer verification.
- Packaged in a 2 L bottle for extended use and fewer changeovers.
- Supports routine accuracy checks and instrument performance verification.
- Ready-to-use formulation for convenient calibration procedures.
ABclonal Technology TSC1 Rabbit pAb
This gene is a tumor suppressor gene that encodes the growth inhibitory protein hamartin. The encoded protein interacts with and stabilizes the GTPase activating protein tuberin. This hamartin-tuberin complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. This protein also functions as a co-chaperone for Hsp90 that inhibits its ATPase activity. This protein functions as a facilitator of Hsp90-mediated folding of kinase and non-kinase clients, including TSC2 and thereby preventing their ubiquitination and proteasomal degradation. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
ABclonal Technology CYBA Rabbit pAb
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
ABclonal Technology FXYD7 Rabbit pAb
This gene encodes a member of the FXYD-domain family of small membrane proteins, characterized by a 35-amino acid signature sequence starting with PFXYD, containing 7 invariant and 6 highly conserved amino acids. The FXYD family regulates ion transport and includes proteins like FXYD1 (phospholemman), FXYD2 (gamma subunit of Na,K-ATPase), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC), which induce channel activity in expression systems. Transmembrane topology for FXYD1 and FXYD2 shows the N-terminus extracellular and C-terminus cytoplasmic. FXYD7, a novel gene product, has not been characterized as a protein. The sequence is validated by similar human genomic data.
ABclonal Technology GATA2 Rabbit pAb
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
ABclonal Technology CARD8 Rabbit pAb
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
ABclonal Technology CDC5L Rabbit mAb
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
ProteinSimple pI MARKERS, 10.45
We have a wide range of markers for pI determination that will give you both consistent and accurate measurement of isoelectric point on your iCE system. They can be used for whole-column and single-point capillary isoelectric focusing (cIEF) detection to measure your sample protein's isoelectric point, and for quality control of sample analysis. You'll get 200 µL of pI marker stock solution in every vial.
ACROBiosystems Star Ribbon Pre-stained Protein Marker (2.7-40 kDa)
This product is a mixture of nine highly purified pre-stained proteins ranging from 2.7 kDa to 40 kDa. The 40 kDa band is orange, 10 kDa band is green, and other bands are blue. It is designed for observing protein separation during SDS-PAGE, verifying western transfer efficiency on membranes, and approximating the size of proteins.