Protein Molecular Weight Markers
New England Biolabs, Inc. Unstained Protein Standard, Broad Range – 150 gel lanes
The Unstained Protein Standard, Broad Range is a mixture of highly pure, recombinant proteins that resolves into 13 sharp bands from 10-200 kDa when electrophoresed and stained with Coomassie Brilliant Blue R-250 or other commercially available, ready-to-use protein stains.
Sigma Aldrich Fine Chemicals Biosciences ECLTM Prime Western Blotti
Amersham(TM) ECL(TM) Prime is a highly sensitive reagent characterized by stable signal emission allowing for the possibility of repeated exposures and making it easier to process several blots in the same experimental run. The high intensity of the emitted signals means that proteins can be detected using highly diluted primary and secondary antibodies contributing to low background and reducing consumption of reagents.Amersham(TM) ECL(TM) Prime consolidates and builds on the benefits of Amersham(TM) ECL(TM) Plus and Amersham(TM) ECL(TM) Advance to deliver a detection system that is sensitive stable precisely quantitative across a wide dynamic range of protein levels and conservative in its consumption of expensive antibody reagents.
ABclonal Technology RBX1 Rabbit pAb
This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.
ABclonal Technology FGB Rabbit pAb
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
ABclonal Technology CD2BP2 Rabbit pAb
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
ABclonal Technology CHCHD1 Rabbit pAb
Enables RNA binding activity. Predicted to be involved in mitochondrial translation. Located in cytosol, mitochondrion, and nuclear lumen.
ABclonal Technology OCIAD2 Rabbit pAb
Predicted to be involved in endocytosis, hematopoietic stem cell homeostasis, and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to act upstream of or within response to bacterium. Predicted to be located in Golgi apparatus, endosome, and lysosome.
![ABclonal Technology [KO Validated] MYOF Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000104718.jpg-250.jpg)
ABclonal Technology [KO Validated] MYOF Rabbit pAb
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
ABclonal Technology MAN1A2 Rabbit pAb
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.
ABclonal Technology SEMA4F Rabbit pAb
This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.
ABclonal Technology PSMC5 Rabbit pAb
The 26S proteasome is a multicatalytic proteinase complex consisting of a 20S core and a 19S regulator. The 20S core has 4 rings made of 28 subunits, while the 19S regulator includes a base with ATPase subunits and a lid with non-ATPase subunits. Proteasomes, located throughout eukaryotic cells, cleave peptides in an ATP/ubiquitin-dependent process. The immunoproteasome processes class I MHC peptides. This gene encodes an ATPase subunit, part of the triple-A family of ATPases with chaperone-like activity. Beyond proteasome function, it may also participate in transcriptional regulation, interacting with thyroid hormone and retinoid X receptors. Two isoforms of this gene are produced by alternative splicing.