Protein Molecular Weight Markers
ABclonal Technology MMACHC Rabbit pAb
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
ABclonal Technology FAM98A Rabbit pAb
Enables protein methyltransferase activity. Involved in positive regulation of cell population proliferation, positive regulation of gene expression, and protein methylation. Predicted to be part of tRNA-splicing ligase complex.
Biotium Primary Antibody Mouse Fab kappa N2507.MFAB CF660C 1/EA
Alpaca Anti-Mouse (Fab) Kappa rVHH (N2507 MFAB) is a recombinant Alpaca VHH antibody that recognizes the mouse kappa light chain and is validated for IF flow and WB STORM-compatible CF660C dye has Ex/Em at 667/685 nm Unit size 500 uL at 0 1 mg/mL
ABclonal Technology S100A16 Rabbit pAb
Enables calcium ion binding activity and protein homodimerization activity. Predicted to act upstream of or within response to calcium ion. Located in several cellular components, including cytosol, extracellular space, and nucleolus.
ABclonal Technology WBSCR27 Rabbit pAb
This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23.
ABclonal Technology SAMM50 Rabbit mAb
This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.
ABclonal Technology FOXF1 Rabbit mAb
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the regulation of pulmonary genes as well as embryonic development.
ABclonal Technology ODF2 Rabbit pAb
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as Cenexins, encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers.
ABclonal Technology ZNF384 Rabbit pAb
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewings sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
ABclonal Technology SAMD3 Rabbit pAb
SAMD3 (Sterile Alpha Motif Domain Containing 3) is a Protein Coding gene. Diseases associated with SAMD3 include Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma. An important paralog of this gene is CNKSR2.
ABclonal Technology SNAP25 Rabbit pAb
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
ABclonal Technology NHLH1 Rabbit pAb
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).
ABclonal Technology GPR141 Rabbit pAb
GPR141 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).
ABclonal Technology EPN2 Rabbit pAb
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Biotium Primary Antibody Mouse Fab kappa N2507.MFAB CF498 1/EA
Alpaca Anti-Mouse (Fab) Kappa rVHH (N2507 MFAB) is a recombinant Alpaca VHH antibody that recognizes the mouse kappa light chain and is validated for IF flow and WB Green fluorescent STORM-compatible CF498 dye has Ex/Em at 498/519 nm Unit size 500 uL at 0 1 mg/mL