Protein Molecular Weight Markers
Medchemexpress LLC HY-W016009 100mg Medchemexpress, 2'-Deoxyadenosine-5'-monophosphate CAS:653-63-4 Purity:>98%
Medchemexpress, HY-K1011 250 μL 3 Color Prestained Protein Marker (10-190 kDa) CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ABclonal Technology RASD1 Rabbit pAb
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimers disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology MRPL32 Rabbit pAb
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp.
ABclonal Technology MTMR6 Rabbit pAb
Enables phosphatidylinositol-3,5-bisphosphate phosphatase activity and phosphatidylinositol-3-phosphatase activity. Involved in phosphatidylinositol dephosphorylation. Located in cytoplasm and nuclear envelope.
ABclonal Technology ETV6 Rabbit pAb
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
ABclonal Technology GSTT2 Rabbit pAb
The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations.
![ABclonal Technology [KO Validated] PHD2/EGLN1 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000107558.jpg-250.jpg)
ABclonal Technology [KO Validated] PHD2/EGLN1 Rabbit pAb
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
ABclonal Technology SPIRE2 Rabbit pAb
Predicted to enable actin binding activity. Involved in establishment of meiotic spindle localization, formin-nucleated actin cable assembly, and positive regulation of double-strand break repair. Predicted to be located in cytoskeleton, cytosol, and plasma membrane. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. Predicted to colocalize with cleavage furrow.
ABclonal Technology TUBGCP6 Rabbit pAb
The protein encoded by this gene is part of a large multisubunit complex required for microtubule nucleation at the centrosome.
ABclonal Technology ARCN1 Rabbit pAb
This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking.
ABclonal Technology COL5A1 Rabbit pAb
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants.
ABclonal Technology DOK4 Rabbit pAb
Predicted to be involved in positive regulation of MAPK cascade and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within nervous system development. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
ABclonal Technology COPG2 Rabbit pAb
Predicted to enable structural molecule activity. Involved in intra-Golgi vesicle-mediated transport. Part of COPI vesicle coat.
ABclonal Technology PAPD7 Rabbit pAb
The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described.
ABclonal Technology UCP3 Rabbit pAb
Mitochondrial uncoupling proteins (UCPs), part of the mitochondrial anion carrier proteins (MACP) family, dissociate oxidative phosphorylation from ATP synthesis, releasing energy as heat. UCPs transfer anions across the mitochondrial membrane and reduce the mitochondrial membrane potential in mammalian cells. This gene, primarily expressed in skeletal muscle, encodes a protein that may protect mitochondria from lipid-induced oxidative stress. Its expression increases when fatty acid supplies exceed mitochondrial oxidation capacity, aiding in fatty acid export. UCPs contain three solcar protein domains typical of MACPs. Two splice variants of this gene have been identified.