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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Instruments, accessories, software, and other products designed to facilitate automation within a laboratory or industry setting. Products can be used to set up, perform, and/or collect data from various processes and can be programed to meet protocol requirements.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
SGI-1027 is a non-nucleoside DNA methyltransferase (DNMT) inhibitor for research use that inhibits DNMT1, DNMT3A, and DNMT3B; reported IC50 values include 12.5 μM (DNMT1), 8 μM (DNMT3A), and 7.5 μM (DNMT3B).
Non-nucleoside DNMT inhibitor active against DNMT1, DNMT3A, and DNMT3B.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Also available in 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer Non-Hodgkins Lymphoma and Relapsed/Refractory Leukemias. purity: 99%
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay 50- and 10-fold selective versus Pim2 and Pim3 also potent to Flt3 and haspin SGI-1776 induces apoptosis and autophagy
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PDK1-IN-RS2 is a substrate-selective small-molecule inhibitor of 3-phosphoinositide-dependent protein kinase-1 (PDK1). It mimics the peptide docking motif (PIFtide) and is used in biochemical and cellular studies to probe PDK1-dependent signaling within the PI3K/Akt/mTOR pathway.
Substrate-selective PDK1 inhibitor (Kd ≈ 9 μM).
Useful for studying PI3K/Akt/mTOR pathway and downstream kinase activation.
Chemical formula C15H9ClN2O2S3; molecular weight 380.89 g/mol.
Available as a 5 mg solid suitable for assay preparation and compound screening.
High purity (reported 98.49%) for reliable biochemical results.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More