Oligonucleotides
Medchemexpress LLC ODN 1018 | 937402-51-2 | DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A) | 1 MG
ODN 1018 (1018 ISS) is a TLR9 agonist and immune modulator. It exhibits adjuvant activity and augments CD8+ T cell responses with LNP-encapsulated OVA peptides. It triggers sustained suppression of allergic airway inflammation and can be used for the research of allergic asthma and systemic lupus erythematosus.
- TLR9 agonist and immune modulator
- Exhibits adjuvant activity
- Augments CD8+ T cell responses with LNP-encapsulated OVA peptides
- Triggers sustained suppression of allergic airway inflammation
- Used for research of allergic asthma
- Used for research of systemic lupus erythematosus
Medchemexpress LLC Odn 1826 (sodium) | 202668-42-6 | 99.7% | 6364.1 | 5 MG
ODN 1826 (CpG 1826) is a class B CpG oligodeoxynucleotide that functions as a TLR9 agonist for research use. Supplied as a solid (sodium salt), it is used to stimulate innate immune responses, induce nitric oxide and iNOS production, and enhance apoptosis and immune surveillance in preclinical models.
- Class B CpG oligodeoxynucleotide that activates TLR9.
- Stimulates innate immune responses and enhances immune surveillance.
- Induces nitric oxide (NO) and inducible nitric oxide synthase (iNOS) production.
- Used in tumor immunology, vaccine adjuvant research, and atherosclerosis models.
- Available as a solid sodium salt with high reported purity.
TWD Scientific LLC Oligo dT BioXbeads 1 m Beads 100mL (5mg/mL)
Oligo dT BioXbeads 1 m Beads 100mL (5mg/mL)
Cell Biologics Cre-Expressing Porcine Primary Prostate Epithelial Cells
Cre-Expressing Porcine Primary Prostate Epithelial Cells
Cell Biologics Cre-Expressing Porcine Primary Thyroid Microvascular Endothelial Cells
Cre-Expressing Porcine Primary Thyroid Microvascular Endothelial Cells
BIOHIPPO AAV-hSyn-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the hSyn promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cell Biologics Cre-Expressing Rat Primary Esophageal Smooth Muscle Cells
Cre-Expressing Rat Primary Esophageal Smooth Muscle Cells
Cell Biologics Cre-Expressing Rabbit Primary Spleen Epithelial Cells
Cre-Expressing Rabbit Primary Spleen Epithelial Cells
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein)(rTFF1/1091), CF568 conjugate, 0.1mg/mL
Recognizes a polypeptide of 6. 5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelih
Biotium CD43 (T-Cell Marker) (rSPN/1094), CF405S conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab