Oligonucleotides
eMolecules Broadpharm / Cy55 alkyne / 1mg / 296213727 / BP-22529 / 96.000 / 1628790-37-3 / MFCD28385530 / 656.310 / C43H46ClN3O
Broadpharm / Cy55 alkyne / 1mg / 296213727 / BP-22529 / 96.000 / 1628790-37-3 / MFCD28385530 / 656.310 / C43H46ClN3O
Bioss KD-Validated NHERF1 Rabbit Rab
NHERF Family PDZ Scaffold Protein 1 Primary Antibody Unconjugated Public Immunogen Range 51-99/249 Host Species Rabbit Target Species Human Rat Clonality Monoclonal Applications WB Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
ABclonal Technology HES1 Rabbit pAb
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Genscript Corporation CD43 His Mouse
CD43 is a large transmembrane protein involved in T cell activation Previous studies of CD43-/- mice in viral models have demonstrated a role for CD43 in Th1/Th2 skewing activation of Foxp3 Treg and T cell apoptosis CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage CD43 is directly involved in the contact between cells participating in a series of events such as signaling adherence and host parasite interactions
ABclonal Technology C6 Rabbit pAb
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
ABclonal Technology GAPDH Rabbit pAb
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase family, known as a moonlighting protein due to its multiple distinct functions. It catalyzes an important step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate with NAD and inorganic phosphate. The protein also has uracil DNA glycosylase activity in the nucleus and antimicrobial properties against E. coli, P. aeruginosa, and C. albicans. Additionally, similar proteins in mice have been linked to regulating mRNA stability, nitrosylating nuclear proteins, and acting as a transferrin receptor on macrophage surfaces. Many pseudogenes related to this gene exist in the human genome. Alternative splicing generates multiple transcript variants.
ABclonal Technology CEBPA Rabbit pAb
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
ABclonal Technology Von Hippel Lindau/VHL
This gene encodes a component of a ubiquitination complex The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF) which is a transcription factor that plays a central role in the regulation of gene expression by oxygen In addition to oxygen-related gene expression this protein plays a role in many other cellular processes including cilia formation cytokine signaling regulation of senescence and formation of the extracellular matrix Variants of this gene are associated with von Hippel-Lindau syndrome pheochromocytoma erythrocytosis renal cell carcinoma and cerebellar hemangioblastoma
BIOHIPPO AAV-NPY-Cre-WPRE-bGH-polyA
Recombinant adeno associated virus expressing Cre under the NPY promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-Oxytocin-Cre-WPREs
Recombinant adeno associated virus expressing Cre under the Oxytocin promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-hSyn-Cre-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre fused to EGFP under the hSyn promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC sEH inhibitor-1 (compound TCPU) | 1208549-68-1 | 99.6% | 50 MG
sEH inhibitor-1 (TCPU) is a potent, orally active inhibitor of soluble epoxide hydrolase (sEH) used in preclinical research. It exhibits sub-nanomolar to low-nanomolar potency against human and murine sEH and is supplied as a research-grade powder.
- Potent sEH inhibition: IC50 0.4 nM (human), 5.3 nM (murine).
- Chemical formula C17H20F3N3O3, molecular weight 371.35 g/mol.
- High purity (~99.6%) suitable for research use.
- Supplied as a powder; recommended storage at -20°C for long-term, 4°C for shorter-term.
- Used in studies of inflammation, cardiovascular disease, and metabolic disorders.
- Available in a 50 mg pack size.
Cayman Chemical VHL LIgnd 1hydrochlorIde 10mg
A PROTAC building block; VHL E3 binding portion of BET PROTAC MZ1
ABclonal Technology GPC4 Rabbit pAb
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3 end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
ABclonal Technology NCKAP1 Rabbit pAb
Contributes to small GTPase binding activity. Involved in Rac protein signal transduction, positive regulation of Arp2/3 complex-mediated actin nucleation, and positive regulation of lamellipodium assembly. Located in extracellular exosome and focal adhesion. Part of SCAR complex.