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Oligonucleotides with a wide variety of applications in microarrays, gel shift assays, artificial gene synthesis, PCR, DNA sequencing, molecular cloning, and other custom procedures. Available in multiple primer lengths; may be pre-designed or random.
The AccuTrak™ HBV DNA Genotype Qualification Panel is a 9-member validation tool essential for developing and evaluating hepatitis B virus genotype test methods. This panel includes eight HBV DNA positive plasma samples and one negative sample, providing dependable material for optimal assay performance. Its Research Use Only status reinforces its significance for diagnostic manufacturers and clinical laboratories in advancing viral diagnostics.
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A patient-derived next-generation cancer model generated by the Human Cancer Models Initiative (HCMI). HCM-CSHL-0730-C25 (ATCC No. PDM-423) was isolated from primary pancreatic cancer tissue. This tumor-derived model can be used in basic research and pharmacological screening applications. Data for the tumor-derived organoid model is available at the GDC. Additional molecular characterizations may be available at the GDC. Additional controlled data may be available via dbGaP.
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The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PROTAC STING degrader-3 is a STING PROTAC degrader that induces STING degradation via the ubiquitin-proteasome pathway. It exerts anti-inflammatory effects by inhibiting STING/TBK1/NF-κB signaling and has renal protective effects, being used in the study of acute kidney injury (AKI).
Sting PROTAC degrader (DC50: 0.62 μM)
Induces STING degradation via ubiquitin-proteasome pathway
Exerts anti-inflammatory effects by inhibiting STING/TBK1/NF-κB signaling
Renal protective effects for acute kidney injury (AKI) studies
Potently degrades STING protein in THP-1 cells
Blocks STING/NF-κB downstream signaling axis in HK-2 cells
Demonstrates selective degradation of STING protein
Favorable in vitro safety profile
Improves renal function and survival in AKI mice
Suppresses expression of STING proteins and inflammatory factors
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More