Oligonucleotides
Apexbio Technology LLC EZ Cap Human PTEN mRNA (ψUTP) 5x1mg (1mg/mL)
PTEN mRNA encodes a a tumor suppressor gene (Phosphatase and Tensin homolog deleted on chromosome 10) that antagonizes the activity of PI3K a key enzyme involved in anti-apoptotic and pro-tumorigenic Akt activation EZ Cap Human PTEN mRNA ( UTP) is provided at 1 mg/mL This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The incorporation of UTP and addition of poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo Furthermore the poly(A) tail significantly contributes to improving the efficiency of translation initiation
Medchemexpress LLC sEH inhibitor-1 (compound TCPU) | 1208549-68-1 | 99.6% | 50 MG
sEH inhibitor-1 (TCPU) is a potent, orally active inhibitor of soluble epoxide hydrolase (sEH) used in preclinical research. It exhibits sub-nanomolar to low-nanomolar potency against human and murine sEH and is supplied as a research-grade powder.
- Potent sEH inhibition: IC50 0.4 nM (human), 5.3 nM (murine).
- Chemical formula C17H20F3N3O3, molecular weight 371.35 g/mol.
- High purity (~99.6%) suitable for research use.
- Supplied as a powder; recommended storage at -20°C for long-term, 4°C for shorter-term.
- Used in studies of inflammation, cardiovascular disease, and metabolic disorders.
- Available in a 50 mg pack size.
Medchemexpress LLC CDK7/9 tide | >99.7% | 2690.00 | 10 MG
CDK7/9 tide is a synthetic peptide substrate designed for the study of cyclin-dependent kinases 7 (CDK7) and 9 (CDK9). This research-use-only product is provided as a white to off-white solid and is soluble in water, making it suitable for in vitro applications.
- Sequence shortening: YSPTSPSYSPTSPSYSPTSPSKKKK
- Formula: C120H185N29O41
- Appearance: White to off-white solid
- Solubility: 10 mg/mL in H₂O (requires ultrasonic)
- Storage (powder): -80°C for 2 years, -20°C for 1 year
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Cayman Chemical VHL LIgnd 1hydrochlorIde 10mg
A PROTAC building block; VHL E3 binding portion of BET PROTAC MZ1
Meso Scale Discovery R-PLEX Human PTEN total ASY
The R-PLEX Human PTEN Total Assay Kit from Meso Scale Discovery is used to quantitatively measure levels of total PTEN protein in human cell and tissue lysates The assay uses an electrochemiluminescent detection method and provides high sensitivity a broad dynamic range and requires low sample input The kit includes a 96-well plate coated with capture antibody a detection antibody conjugated to an electrochemiluminescent label and calibrators and controls to generate a standard curve and validate assay performance The assay takes approximately 4 hours to complete and is suitable for research use only
Invivogen ODN 2006 control (ODN 2137), 1 mg
ODN 2006 Control (ODN 2137) contains GpC dinucleotides instead of CpGs and can be used as a negative control for ODN 2006 (type B, with a preference for human TLR9).
Cayman Chemical VHL LIgnd 1hydrochlorIde 25mg
A PROTAC building block; VHL E3 binding portion of BET PROTAC MZ1
Enzo Life Sciences IHC tissue primer (100ml)
The IHC tissue primer is a universal enzyme blocking reagent to use in horse radish peroxidase (HRP) and alkaline phosphatase (AP) based immunohistochemical staining procedures done on paraffin tissue sections, frozen tissue sections and cell smears to suppress nonspecific staining due to endogenous enzyme activity. Formulation: Liquid. Tissue primer. TRIS-based alkaline solution with 30% H2O2. Long Term Storage: +4°C. Handling: Store tightly sealed in the dark. Protect from light. Applications: IHC .