High-Specificity Pfu HS Mix is a combination of the latest advances in buffer chemistry and PCR enhancers and stabilizers, together with an aptamer-mediated hot-start polymerase, dNTPs, and MgCl2. The advanced buffer chemistry has been developed for fast, highly reproducible, multiplex PCR, with a fidelity 130x higher than Taq, it is designed for superior sensitivity and specificity, making High-Specificity Pfu HS Mix perfect for DNA target enrichment and NGS library amplification.